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ascV

Victor ID 4093
Gene Name ascV
Sequence Strain (Species/Organism) Aeromonas salmonicida subsp. salmonicida A449
NCBI Gene ID 4999240
NCBI Protein GI 145301453
Locus Tag ASA_P5G070
Genbank Accession CP000646
Protein Accession YP_001144292
Other Database IDs UniProtKB-ID: A4SUH2_AERS4
UniRef100: UniRef100_A4SUH2
UniRef90: UniRef90_A4SUH2
UniRef50: UniRef50_A1JU76
UniParc: UPI00000C0511
EMBL: CP000646
EMBL-CDS: ABO92544.1
RefSeq_NT: NC_009350.1
GenomeReviews: CP000646_GR
KEGG: asa:ASA_P5G070
eggNOG: COG4789
HOGENOM: HBG595253
OMA: LESEQPE
ProtClustDB: CLSK862127
BioCyc: ASAL382245:ASA_P5G070-MONOMER
Taxonomy ID 382245
Plasmid No 5
Gene Starting Position 68768
Gene Ending Position 70933
Gene Strand (Orientation) -
Protein Name AscV protein
Protein pI 6.35
Protein Weight 73360.3
Protein Length 721
DNA Sequence 
>gi|145301385:68768-70933 Aeromonas salmonicida subsp. salmonicida A449 plasmid 5, complete sequence
CTCACAGGCAGACCCTCCCGAGGGGCTGGATATTGATCTGCTGGGTCAGCTCCTGATAGGAGAGCACCGG
CAGGGCATGGTAATCCCCCTCGATGAGCTTGCGCACATAGCGGCGGATATCCATGGAGACAATGAGCACC
GGTTTGTTCTGCATCTGGGCCAGATCACCGACGGTGTGGCGCACCTGATCGAGGAAGCTCTGGGTAATAG
TGGGATCGAGCGCCAGATAGCTGCCGGCACTAGTCTGGCGAATGCCGCCGCGGAGCTGCTCCTCCACCTG
CTGATCGAGCAGATAGGCAGGCAAAATGTTGTTGCCGTTGGCGTACTTGTAGCAGATGTAGCGCTTGAGG
CTGCTACGGATGTACTCGGTGAGCTGCACCACATCCTTCTCCTTCTGGCCCCACTCCACCATCGCCTCGA
GGATGGCGCGCATGTTGCGGATGGAGATATCCTCCCCCACCAGCCGCTGCAAAATTTCGGTCATACGCTG
CAGCGGGATGATGCGTTGCGCCTCCTTCACCAGCTCGCTATAGCTCCCCTCCATCTGCTCCAGCAGGTAG
CGGGTCTCCTGAATGCCGATAAAGTCCTCGGCATATTCCCGCAGCACATGGGATAGATGCCAGGTCATCA
CCTGATCGGTGGTGAGGGTGGCCAGCCGTGACTTCTCCAGTCGCTCCTGATGTTCATTAGCGACCCACAA
GGTCGGTTGTCCCGGCAGTAACGGCGCCCCCTCTTCGTAGGGGATCCCCAGCAGATCGAGCTGGGAGGCG
CTCTCCTGCACCAGCTGATGGCCCGGGCGCAGCAGACCGCGGGCGACCGGCACCTCCTGCAGCTGGATCA
GGTATTCGCCAGGCCCCATCCCCTCGTTGAAACGCAGGTGAATACCCGGGAAAGGCACCCCGAGATCGAG
ATAGAGGGCGCGGCGCACCCGCACCAGTTCGTCGTTGAGGGCAATCGCCTCCAGCTCGGCCTGCAAAGCA
GCATCCACATCGATAAGGAGCGGCACCGTCATGGCAAACTCCTCCTTCTCCCCCAGCTTGCCCCGCGGCT
TGCTGCCCGGTTTTGGCTTGCTGCGGGCAGCTGGGGCCCCGGCCCCCTGCGCCAGCACGGCAGGAAGATC
CTGACTGTTGCTGCTTTGCGCCTTGCGTTGTCGCAAGCCGATAAAGTAACCGCCCGCCGTGACGATGGCC
GACAGCGCAAAGAAGGTGATCATCGGGAAGCCCGGGATCAACCCGAACAGCACCAGCAGCAGACCGCCGA
TCAGTAGCGCCTTGGGCTGGGCCACCACCTGGGCGCCGATATCGGTACCCAGATCGGAAGACTCTTCGGA
GGAGACCCGGGTGACGATAATGCCCGCGGTGATGGCGATCAGCAGCGCCGGCACCTGGGAGACCATGCCA
TCACCCACCGTCAGGATGGAGTAGAGCTGCAGCGCATCGGCGGCGGATAACCCCTTCTGGGTCACCCCGA
TGGTGACGCCACCGAGGATGTTGACGAAGATGATGATGAGGCCCGCGATGGCGTCCCCCTTCACAAACTT
CATGGCGCCATCCATGGAGCCGAACATCTGGCTCTCCTTCTCGATGACCCCGCGGCGATCCCGCGCCTCG
TGCACGTCGATCACCCCGGCGCGCATGTCACCATCGATACTCATCTGCTTACCCGGCATGGCATCGAGGG
AAAAGCGGGCGCTCACCTCGGCGACCCGCTCCGAGCCCTTGGTGATCACCAGAAACTGGACGATGGTGAT
GATGAGGAAGATGACGATCCCCACCACCAGATTGCCCCCCACCACGAAGTTGCCGAAGGTGTAGACTATC
TGCCCCGCATCAGCCTGCAGCAGGATCATCCGGGTGGTACTCACCGACAAGGCAAGCCGGAACAGGGTGG
TGATCAGCAGCACCGCCGGAAAGGCGGAGAACTGCAGCGGCGAATTGATATAAACCGCCATCATCAGCAG
TACCACCGAGATGGTCATGTTGATGGCAATCAGGATATCGAGGGCCACCGGCGGCAGCGGCAAGACCATC
ATAAAGACGATGGCCAGCAGCAGGATCGCCAGCATGATGTCCTTGCGTTCGCCTATCCGGCGCAGCAACT
CAAGGGTGCGTTGATTCATTCTGCTCTTCCAGTTCGAGGTATTGTTGATAGGCAAAACGGGCTTCA
Protein Sequence 
>gi|145301453|ref|YP_001144292.1| AscV protein [Aeromonas salmonicida subsp. salmonicida A449]
MKPVLPINNTSNWKSRMNQRTLELLRRIGERKDIMLAILLLAIVFMMVLPLPPVALDILIAINMTISVVL
LMMAVYINSPLQFSAFPAVLLITTLFRLALSVSTTRMILLQADAGQIVYTFGNFVVGGNLVVGIVIFLII
TIVQFLVITKGSERVAEVSARFSLDAMPGKQMSIDGDMRAGVIDVHEARDRRGVIEKESQMFGSMDGAMK
FVKGDAIAGLIIIFVNILGGVTIGVTQKGLSAADALQLYSILTVGDGMVSQVPALLIAITAGIIVTRVSS
EESSDLGTDIGAQVVAQPKALLIGGLLLVLFGLIPGFPMITFFALSAIVTAGGYFIGLRQRKAQSSNSQD
LPAVLAQGAGAPAARSKPKPGSKPRGKLGEKEEFAMTVPLLIDVDAALQAELEAIALNDELVRVRRALYL
DLGVPFPGIHLRFNEGMGPGEYLIQLQEVPVARGLLRPGHQLVQESASQLDLLGIPYEEGAPLLPGQPTL
WVANEHQERLEKSRLATLTTDQVMTWHLSHVLREYAEDFIGIQETRYLLEQMEGSYSELVKEAQRIIPLQ
RMTEILQRLVGEDISIRNMRAILEAMVEWGQKEKDVVQLTEYIRSSLKRYICYKYANGNNILPAYLLDQQ
VEEQLRGGIRQTSAGSYLALDPTITQSFLDQVRHTVGDLAQMQNKPVLIVSMDIRRYVRKLIEGDYHALP
VLSYQELTQQINIQPLGRVCL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ascV mutant is attenuated in rainbow trout model (Burr et al., 2005).
COG COG4789U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Burr et al., 2005: Burr SE, Pugovkin D, Wahli T, Segner H, Frey J. Attenuated virulence of an Aeromonas salmonicida subsp. salmonicida type III secretion mutant in a rainbow trout model. Microbiology (Reading, England). 2005; 151(Pt 6); 2111-2118. [PubMed: 15942017].