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FTL_1672

Victor ID 409
Gene Name FTL_1672
Sequence Strain (Species/Organism) Francisella tularensis
NCBI Gene ID 3950922
NCBI Protein GI 89256945
Locus Tag FTL_1672
Protein Accession YP_514307.1
Taxonomy ID 119857
Gene Starting Position 1605426
Gene Ending Position 1608539
Gene Strand (Orientation) +
Protein Name Transporter AcrB/AcrD/AcrF family
DNA Sequence 
>gi|89255449:1605426-1608539 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
AATGCGTCTTATTGATCTTTTTATCAGAAGGCCAGTATTATCCCTTTCAATAAGCTTTATGATTATTGTC
GTTGGGGTTGGTTCATTTTTTAAACTTCAGGTTAGACAGTATCCGTACATAGATAGCGCGACAATTACAG
TCACAACATCATATCCAGGAGCAAATCCAGCCACTATTCAAGCATTTGTTACTAGACCTTTAGAAGCTGC
AGTTGGCTCATCAAAAGGTATCGATTATATGACTTCTGAATCAGCACTAGGAACTAGTACAATCACTGTA
TATGTAAAGCTTGGATATAATACAAACGATGTACTCTCAGAAGTAGTACAAAATGTTAACTCTATACTTA
ATCAGTTACCACAAGATGCCTACTCTCCTGCTATCAAACTTAATTCTGCGGATAACTTCCCTTCTTTGAT
TTTAGCTTTTACTAGTAAAACAATGAATACTTCAGAGATATCGGCATATATAAACTCTGAGCTGACTCCA
AAACTACTTGCTGAGGGTGGTTTATCAGAAATTAATGTCTGGGGTAATATGCCATATGCAATGCGTATTT
ACCCAAATAAAACTCGTATGGCCGAGTATGGTATAACACCAACAGAACTAGTAACAGCTATTGGTTCAAA
TAGTTTAGTTTCAGCAGGTGGTCAAATCCAAGGTCCATACCTAAACTATACGCTTAATCCTGAAACCAGC
ATGTCTACAGCTCAAGAATATAGAAATCTGATTATCAAGAAAAGCGATAATCAAATAGTTCGCCTTAGCG
ATGTAGCTAGAGTAGAGCTAGGTGCACAAAACTATAACTCCTCAGTATATTTTGATGGTAAAAATGCCGT
GCTTGCAGGTGCTGTTGTATCGCCTGAAGAGAATCCATTAGATGTTGTCAACCGATTAGTCAAACAGCTT
CCAAATATCAAAGCTTCTCTACCTAATGGCTTAAATGTTGATGTTGCTTATAACAGTACCTTATATATAG
AGAGTTCTATTGATGAAGTATTACATACTTTACTAGAAGCCGTAATTATTGTATCTATAGTAATGTTCCT
ATTTTTAGGCTCATTACGAGCTATTATTGTACCAATAATTGCTATTCCCTTATCGATTATAGGATCATTT
TTCCTTATGAGTATTATGGGATTCTCGATTAACTTAATTACATTATTAGCGATGATTTTAGCTATAGGAT
TAGTAGTTGATGATGCAATTGTTGTGCTAGAGAATATTTATCGTCATATTGAAGAAGGTATGGAGCCTTT
TGCTGCTGCGATCAAAGGTGCCCGAGAAATTGCTAATCCCGTGATACTAATGACTCTAACGCTTATAGTT
GTTTATGCTCCTATCGGTATGATGGGTGGATTTACTGGACAACTTTTCACAGAATTTGCTTACTCACTTG
CCGGTGCTGTGCTTATCTCTGGTATAGTTGCTTATACTCTCTCGCCAATGATGTGCTCAAAGGTTCTTAA
CCGTGAAATGATGAGCTCAAAGCTAGTCAAATTTATTGATAATGTTTTTAGTAAACTAGCAGCAAAGTAC
AAAGCCTTACTAATGTTTGTTTTAGATATCAAACCTGCCATAGCAATTGTTGGAATTATAGTTTTAGCAA
GCTGTTTTATCATGGGGAAAGGTATTAAATCTGAATTAGCTCCAAATGAAGATATGGGCTTCTTAGGAGT
TATGGGACAAGCTCCGTCATCAGCAAATATTAACTATCTAGAGACCTTTGGCAAAAAGCTAGCAAACACA
CTTGATGAAATTCCAGGTAAACAAAATGTCTTTATTCTTAATGGTGTAATGAGCTCTAATGTGATTTTTG
GCGGTTTTATTATGCAACCTTGGGATGAACGAAAAATATCCCAGCAACAAGCTGCAAACATTGCTCAAGC
CAAAGTCACTGAATTACCTGGTGTTCAAACATATACATACCAAACGCCTGCTTTACCAGGGATTCCACGC
GGAGCTCCACTTTCATTAGTTATTCAAAGTGTCAATGACTATGAAGCTATCGATGAGATCACTAATAAAA
TCATTGCAAAAATGATGAGCAGTGGATTATTTGTATTTGCTCAGAGTGACCTTAAGTTTGATAATCCTAT
TGTTGATATTAATATTGATCGTGATAAGGCTGGAATTTTAGGTATTACAATGTCTGATATTGCTAAAACT
CTAGGTTATTCATACGCCGGTGGTTATATTAATTATTTCTTTTTAAAAGGCTATAGTTTCCAAGTTATTC
CACAGTTAGCTAGAAATGAGATGCTTACTCAGGAACAACTTGGTAATATTTATATCCGTTCTGATGAAAT
GAATAAACTATTTGACTCTGAGGTACCATTATCAGCTTTAGTAACCTTCAAAACAGAAGGACAACCTCTT
ACGCTAAATACTTTCCAACAGTTAAATGCATCAACAATTTCAGCTGTTATGGCACCAGGGATAACCCAAG
GACAAGCTATAGAATATGTCCAAAGTGTTGTCAAAAGTATGCTTCCTGAAGGCTTTTCATATAACTTCTC
CGGTTCAGCACGTCAATATAACGAAAATGGTAATACAATGATGGTTGCATTTGCATTTGCGATTGTATTG
ATATTCTTAGCATTATCAGCACAGTTTGAAAGTTTTAGAGACTCGCTTGTAATTTTAGTTACTATTCCAA
TGGCAATCTCTGGAGCATTGATTCCACTCTATGTTGGGCAGTACTTAGGAGCTAGTTGGGCATCTTTGAA
TATTTATACTCAGCTAGGCTTAGTTACTCTAATAGGCTTAATATCTAAACAAGGTATTATGGTTGTTGAG
TTTGCCAATCACTTACAAAAACATAATGGCATGAACAAATATGATGCGATTGTTACATCTTCGTCTCAAC
GTCTAAGACCAATATTAATGACTGTATCAGCAATGGTTGTTGGCGTAATACCTCTTGTAACCTCATCTGG
AGCTGGTGCAATTAGTAGAAACTGTATCGGTGTAGTTATATCAAGTGGTTTAGTTATTGGTGCAATATTC
TCACTATTTGTACTACCTGTAGTATATATGTATATAGCCAGTGACAAATCTAAATCAGTCAAAACTGATG
CTGAACAACAACAAATAATAGATCAAATAAAGTA
Protein Sequence 
>gi|89256945|ref|YP_514307.1| AcrB/AcrD/AcrF family transporter [Francisella tularensis subsp. holarctica LVS] MRLIDLFIRRPVLSLSISFMIIVVGVGSFFKLQVRQYPYIDSATITVTTSYPGANPATIQAFVTRPLEAAVGSSKGIDYMTSESALGTSTITVYVKLGYNTNDVLSEVVQNVNSILNQLPQDAYSPAIKLNSADNFPSLILAFTSKTMNTSEISAYINSELTPKLLAEGGLSEINVWGNMPYAMRIYPNKTRMAEYGITPTELVTAIGSNSLVSAGGQIQGPYLNYTLNPETSMSTAQEYRNLIIKKSDNQIVRLSDVARVELGAQNYNSSVYFDGKNAVLAGAVVSPEENPLDVVNRLVKQLPNIKASLPNGLNVDVAYNSTLYIESSIDEVLHTLLEAVIIVSIVMFLFLGSLRAIIVPIIAIPLSIIGSFFLMSIMGFSINLITLLAMILAIGLVVDDAIVVLENIYRHIEEGMEPFAAAIKGAREIANPVILMTLTLIVVYAPIGMMGGFTGQLFTEFAYSLAGAVLISGIVAYTLSPMMCSKVLNREMMSSKLVKFIDNVFSKLAAKYKALLMFVLDIKPAIAIVGIIVLASCFIMGKGIKSELAPNEDMGFLGVMGQAPSSANINYLETFGKKLANTLDEIPGKQNVFILNGVMSSNVIFGGFIMQPWDERKISQQQAANIAQAKVTELPGVQTYTYQTPALPGIPRGAPLSLVIQSVNDYEAIDEITNKIIAKMMSSGLFVFAQSDLKFDNPIVDINIDRDKAGILGITMSDIAKTLGYSYAGGYINYFFLKGYSFQVIPQLARNEMLTQEQLGNIYIRSDEMNKLFDSEVPLSALVTFKTEGQPLTLNTFQQLNASTISAVMAPGITQGQAIEYVQSVVKSMLPEGFSYNFSGSARQYNENGNTMMVAFAFAIVLIFLALSAQFESFRDSLVILVTIPMAISGALIPLYVGQYLGASWASLNIYTQLGLVTLIGLISKQGIMVVEFANHLQKHNGMNKYDAIVTSSSQRLRPILMTVSAMVVGVIPLVTSSGAGAISRNCIGVVISSGLVIGAIFSLFVLPVVYMYIASDKSKSVKTDAEQQQIIDQIK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a FTL_1672 mutant was attenuated for infection of a mouse lung (Su et al., 2007)
COG COG0841V, under V: Defense mechanisms
References
Su et al., 2007: Su J, Yang J, Zhao D, Kawula TH, Banas JA, Zhang JR. Genome-wide identification of Francisella tularensis virulence determinants. Infection and immunity. 2007; 75(6); 3089-3101. [PubMed: 17420240].