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asaI

Victor ID 4087
Gene Name asaI
Sequence Strain (Species/Organism) Aeromonas salmonicida subsp. salmonicida A449
NCBI Gene ID 4994878
NCBI Protein GI 145300630
Locus Tag ASA_3762
Genbank Accession CP000644
Protein Accession YP_001143471
Other Database IDs UniProtKB-ID: A4SS51_AERS4
UniRef100: UniRef100_P70774
UniRef90: UniRef90_Q44058
UniRef50: UniRef50_Q44058
UniParc: UPI00001260E5
EMBL: CP000644
EMBL-CDS: ABO91723.1
RefSeq_NT: NC_009348.1
GenomeReviews: CP000644_GR
KEGG: asa:ASA_3762
eggNOG: COG3916
HOGENOM: HBG298750
OMA: FAGIIEW
ProtClustDB: CLSK729942
BioCyc: ASAL382245:ASA_3762-MONOMER
Taxonomy ID 382245
Gene Starting Position 4055127
Gene Ending Position 4055750
Gene Strand (Orientation) -
Protein Name N-acyl homoserine lactone synthase
Protein pI 6.25
Protein Weight 21830.17
Protein Length 207
DNA Sequence 
>gi|145297124:4055127-4055750 Aeromonas salmonicida subsp. salmonicida A449, complete genome
TTTACTCGGTGACCAGTTCCCTGGCATCGGCATATTCGCCCTGCATGGGGTGGCCGACGGCACGGGCGAA
ACGTTCATCCAGATGAAAGCGGATTCCGACCCCGCGCACGGCGCCCAGATCCACGGCTTGACGGTGACCG
AGTCGCTCTATGGGCAGGCCGAGACGGCGGAAGATACGCTCCACCGGCAGGCTGACCACGGCGACCAGTT
CCCGGATCCCCTTCGCCCTGGCGAAGGCATAAACCTCGCGGAAGATGACGCAGGTCAGCTCGCTCACCCC
GTTGCCCATGCGCGGCGCCCGGTTGGCGTCGATGGCTAGGCGAGTCAGTTCCCACACATCGCTGCTGCGT
GGCGGCGCCTCACCGGCGAGAGCGGTGGGGAATATGCTGGGCAGCATGTAATCCTGGGCGCAACTGAGCA
GACGGATGCAGCCACACAGGCCTTCTTCGTCCTCGATCAGCACCCAATGGGTGTCCGGGGTGTCGAAGCT
GTCCTGCTCCAGACCACGGTGAGACTCCACATCCCAGCCGAGACGATCGGAGAAGACGCGATTACGGAAG
CGATAAAGCTCGTTTTCTACCTCCCATCTGGGGTGTTCTTTTAATTTTCCTTTGAAAACAAGCA
Protein Sequence 
>gi|145300630|ref|YP_001143471.1| N-acyl homoserine lactone synthase [Aeromonas salmonicida subsp. salmonicida A449]
MLVFKGKLKEHPRWEVENELYRFRNRVFSDRLGWDVESHRGLEQDSFDTPDTHWVLIEDEEGLCGCIRLL
SCAQDYMLPSIFPTALAGEAPPRSSDVWELTRLAIDANRAPRMGNGVSELTCVIFREVYAFARAKGIREL
VAVVSLPVERIFRRLGLPIERLGHRQAVDLGAVRGVGIRFHLDERFARAVGHPMQGEYADARELVTE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: asaI mutant is attenuated in fish (Schwenteit et al., 2011).
COG COG3916TQ, under T: Signal transduction mechanisms; Q: Secondary metabolites biosynthesis, transport and catabolism
References
Schwenteit et al., 2011: Schwenteit J, Gram L, Nielsen KF, Fridjonsson OH, Bornscheuer UT, Givskov M, Gudmundsdottir BK. Quorum sensing in Aeromonas salmonicida subsp. achromogenes and the effect of the autoinducer synthase AsaI on bacterial virulence. Veterinary microbiology. 2011; 147(3-4); 389-397. [PubMed: 20708354].