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degP

Victor ID 4030
Gene Name degP
Sequence Strain (Species/Organism) Yersinia enterocolitica subsp. enterocolitica 8081
NCBI Gene ID 4715899
NCBI Protein GI 123441096
Locus Tag YE0741
Genbank Accession AM286415
Protein Accession YP_001005085
Other Database IDs UniProtKB-ID: A1JJQ8_YERE8
UniRef100: UniRef100_A1JJQ8
UniRef90: UniRef90_A4TPX4
UniRef50: UniRef50_P26982
UniParc: UPI00000B1888
EMBL: AM286415
EMBL-CDS: CAL10845.1
RefSeq_NT: NC_008800.1
MEROPS: S01.273
GenomeReviews: AM286415_GR
KEGG: yen:YE0741
NMPDR: fig|630.2.peg.720
eggNOG: COG0265
HOGENOM: HBG585708
OMA: ISINIEG
ProtClustDB: PRK10942
BioCyc: YENT393305:YE0741-MONOMER
Taxonomy ID 393305
Gene Starting Position 861810
Gene Ending Position 863246
Gene Strand (Orientation) +
Protein Name serine endoprotease
Protein pI 8.59
Protein Weight 45391.81
Protein Length 478
Protein Note Also known as gsrA; htrA; ptdprotease Do; required at high temperature; degrades damaged proteins
DNA Sequence 
>gi|123440403:861810-863246 Yersinia enterocolitica subsp. enterocolitica 8081, complete genome
CATGAAAAAAACAACTTTAGTGTTAAGTGCATTGGCATTGAGCATCGGTTTAGCCATGGGGCCGGTTTCT
TCTGTCGTTGCGGCAGAAACGGCCTCTTCCAGCAGCCAGCAGCTCCCTAGCCTGGCGCCAATGCTAGAGA
AGGTAATGCCTTCGGTTGTGAGTATCAATGTGGAGGGAAGTGCTCAGGTAAGTAATGCCGGTGGCATACC
ACCACAGTTCCAGCAATTCTTTGGTGATGATTCGCCATTCTGCCAGGACGGTTCTCCGTTCCAAGGGTCA
CCAATGTGTCAGGGGGGGCCTGGTAGCAGGGGGGGAGCACCCAGCAAGCAGGATTTCCGTGCGCTGGGTT
CTGGCGTAATTATTGATGCTGCTAAAGGTTATGTCGTCACTAATAACCACGTAGTAGATAATGCAACCAA
AATCAATGTTAAGCTCAGTGATGGCCGTAGTTATGAAGCAAAAGTGATTGGTAAAGATCCGCGTACTGAT
ATTGCATTATTGCAGCTGAAAGACGCTAAAAATCTGACTGCGATTAAAATTGCCGACTCCGATCAACTGC
GCGTTGGGGATTATACCGTAGCTATCGGTAACCCATACGGCCTGGGTGAAACCGTCACTTCCGGTATCGT
GTCGGCGTTGGGCCGCAGTGGTTTGAATGTGGAAAACTACGAAAACTTTATCCAGACTGACGCGGCAATT
AACCGTGGTAACTCCGGTGGTGCATTGATCAATCTGAACGGTGAACTGATCGGGATCAACACGGCTATTC
TGGCACCTGATGGCGGCAACATCGGTATCGGTTTTGCTATCCCAAGTAACATGGTGAAAAACCTGACCTC
ACAGATGGTTGAATTTGGTCAGGTGAAACGCGGTGAACTGGGCATTATGGGTACAGAGCTGAACTCTGAG
CTGGCGAAAGCCATGAAGGTTGATGCGCAGAAAGGGGCCTTTATCAGTCAGGTACTGCCAAAATCTGCTG
CAGCTAAAGCAGGGATTAAAGCGGGTGATGTGATTGTCAGCATGAATGGCAAAGCCATCAATAGCTTCGC
TGGCTTCCGTGCCGAGATTGGTACTTTGCCTGTGGGCAGCAAAATGACCTTGGGTCTGTTGCGCGACGGT
AAGCCTGTCAACGTGGAAGTGACATTAGAGCAAAGCAGCCAAACTCAAGTTGATTCAGGCAATCTCTACA
CTGGTATTGAAGGGGCTGAGCTGAGCAACTCTGATGTGAATGGTAAGAAAGGTGTGAAAGTTGATAGTGT
GAAACCTGGCACTGCTGCTGCGCGTATAGGCCTGAAAAAAGGCGATGTCATCATGGGTGTCAACCAGCAA
CCCGTTCAGAATCTGGGTGAGCTGCGGAAAATCCTTGATACCAAACCATCGGTATTGGCATTGAGCATTC
AGCGTGGTGATACTTCACTCTATCTGCTGATGCAGTA
Protein Sequence 
>gi|123441096|ref|YP_001005085.1| serine endoprotease [Yersinia enterocolitica subsp. enterocolitica 8081]
MKKTTLVLSALALSIGLAMGPVSSVVAAETASSSSQQLPSLAPMLEKVMPSVVSINVEGSAQVSNAGGIP
PQFQQFFGDDSPFCQDGSPFQGSPMCQGGPGSRGGAPSKQDFRALGSGVIIDAAKGYVVTNNHVVDNATK
INVKLSDGRSYEAKVIGKDPRTDIALLQLKDAKNLTAIKIADSDQLRVGDYTVAIGNPYGLGETVTSGIV
SALGRSGLNVENYENFIQTDAAINRGNSGGALINLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNLTS
QMVEFGQVKRGELGIMGTELNSELAKAMKVDAQKGAFISQVLPKSAAAKAGIKAGDVIVSMNGKAINSFA
GFRAEIGTLPVGSKMTLGLLRDGKPVNVEVTLEQSSQTQVDSGNLYTGIEGAELSNSDVNGKKGVKVDSV
KPGTAAARIGLKKGDVIMGVNQQPVQNLGELRKILDTKPSVLALSIQRGDTSLYLLMQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: htrA mutant is avirulent in mice (Li et al., 1996).
COG COG0265O, under O: Posttranslational modification, protein turnover, chaperones
References
Li et al., 1996: Li SR, Dorrell N, Everest PH, Dougan G, Wren BW. Construction and characterization of a Yersinia enterocolitica O:8 high-temperature requirement (htrA) isogenic mutant. Infection and immunity. 1996; 64(6); 2088-2094. [PubMed: 8675311].