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msbB

Victor ID 4027
Gene Name msbB
Sequence Strain (Species/Organism) Yersinia enterocolitica subsp. enterocolitica 8081
NCBI Gene ID 4715094
NCBI Protein GI 123442628
Locus Tag YE2386
Protein Accession YP_001006605.1
Other Database IDs UniProtKB-ID: A1JRH3_YERE8
UniRef100: UniRef100_A1JRH3
UniRef90: UniRef90_A1JRH3
UniRef50: UniRef50_P59198
UniParc: UPI0000EB5CE1
EMBL: AM286415
EMBL-CDS: CAL12438.1
RefSeq_NT: NC_008800.1
GenomeReviews: AM286415_GR
KEGG: yen:YE2386
NMPDR: fig|630.2.peg.2314
eggNOG: COG1560
HOGENOM: HBG730280
OMA: VPLFPVY
ProtClustDB: PRK08943
BioCyc: YENT393305:YE2386-MONOMER
Taxonomy ID 393305
Gene Starting Position 2574321
Gene Ending Position 2575283
Gene Strand (Orientation) -
Protein Name lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase
DNA Sequence 
>gi|123440403:2574321-2575283 Yersinia enterocolitica subsp. enterocolitica 8081, complete genome
GTTACAAGTCCTTACGAACATAAGGTTCTATTTCACCTTCTTTGCGGGTTTTCAGCAGTTTTAAAATCCA
GGTATATTGTTCTGGGTTCGGCTTAACCAGCAGTTCAACTTCTTCATTCATACGCCGTGCAATATAAGCA
TCATCCGCATCTGCCAGATCATCCATCGGTGGACGAATATAGATATCAAGGCGATGTTCACGATAATTGT
AAACAGGGAACATTGGCACGATAGCCGCACGACAGACTTTCATCAATCGCCCCACTGCCGGTAGCGTGGC
CTTATAAGTCGCGAAGAAATCAACAAACTCACTTTGCTCAGGGCCATAGTCCTCATCGGGCAAGTAATAC
CCCCAGAACCCCTGACGCACGGAACTAATAAAGGGCTTGATACCACTGTCACGCGCATGGATACGGCCCC
CAAACCGCAAGCGTGCGCTGTTCCATAAATAATCGACAACAGGATTGCGTTGATGATGGAACATACCGGC
GACTGGCTTACCCTGTTCAGCGAGCAACATGGCCGGAATATCAATCGACCAGGCATGGGGCACCAACAAA
ATAACATTGCGCTCCTGTTGTTGCAGTCCATCTAAAATATCCAGTCCATGCCAATGAACCCGCGTCAGCA
CTTTCTTTGGGTCGCGAAAACACAGTTCCGCCATCATCATTAAGGGTTGTGCCGCGGTTGCAAACATTTG
ATCAATAATGTGTTCGCGCTCTGCTTCTGGCAGCTCCGGCATACAATAAAGTAAGTTAATGCGAGCGCGG
CGACGGGCACTTTTAGCAAACTTTCCGGCAACACGCCCGACTCCGGCCAAGAGTGGATCGCGGAGTTTCG
GTGGGACATATGCCATTGCGGCCATGGCCCCAGCCCCTAACCACACCCCCCAAAAACGTGGATGTAGAAA
AGATTTTTTAAATACCGGAATAAAGCCAGCAGCGTCGTTTTTCTCTTTGTGCA
Protein Sequence 
>gi|123442628|ref|YP_001006605.1| lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase [Yersinia enterocolitica subsp. enterocolitica 8081] MHKEKNDAAGFIPVFKKSFLHPRFWGVWLGAGAMAAMAYVPPKLRDPLLAGVGRVAGKFAKSARRRARINLLYCMPELPEAEREHIIDQMFATAAQPLMMMAELCFRDPKKVLTRVHWHGLDILDGLQQQERNVILLVPHAWSIDIPAMLLAEQGKPVAGMFHHQRNPVVDYLWNSARLRFGGRIHARDSGIKPFISSVRQGFWGYYLPDEDYGPEQSEFVDFFATYKATLPAVGRLMKVCRAAIVPMFPVYNYREHRLDIYIRPPMDDLADADDAYIARRMNEEVELLVKPNPEQYTWILKLLKTRKEGEIEPYVRKDL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: msbB mutant has diminished invasion of HeLa cells (Pérez-Gutiérrez et al., 2010).
COG COG1560M, under M: Cell wall/membrane/envelope biogenesis
References
Pérez-Gutiérrez et al., 2010: Pérez-Gutiérrez C, Llobet E, Llompart CM, Reinés M, Bengoechea JA. Role of lipid A acylation in Yersinia enterocolitica virulence. Infection and immunity. 2010; 78(6); 2768-2781. [PubMed: 20385763].