Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

htrB

Victor ID 4026
Gene Name htrB
Sequence Strain (Species/Organism) Yersinia enterocolitica subsp. enterocolitica 8081
NCBI Gene ID 4714987
NCBI Protein GI 123441919
Locus Tag YE1612
Protein Accession YP_001005902.1
Other Database IDs UniProtKB-ID: A1JN09_YERE8
UniRef100: UniRef100_A1JN09
UniRef90: UniRef90_A7FH05
UniRef50: UniRef50_P0ACV2
UniParc: UPI0000EB57F3
EMBL: AM286415
EMBL-CDS: CAL11687.1
RefSeq_NT: NC_008800.1
GenomeReviews: AM286415_GR
KEGG: yen:YE1612
NMPDR: fig|630.2.peg.1578
eggNOG: COG1560
HOGENOM: HBG730280
OMA: INQWVER
ProtClustDB: PRK06860
BioCyc: YENT393305:YE1612-MONOMER
Taxonomy ID 393305
Gene Starting Position 1814332
Gene Ending Position 1815264
Gene Strand (Orientation) -
Protein Name lipid A biosynthesis lauroyl acyltransferase
DNA Sequence 
>gi|123440403:1814332-1815264 Yersinia enterocolitica subsp. enterocolitica 8081, complete genome
GTTACTCATATAGCGAAGGTACGCCCTCTGGCCGGGTTTTAAAACGCCGGTGGAGCCACATGTATTGATC
CGTCGCGCGCTCAATCTCTTTCTCGACCACTTTATTCATAAATGCCGCTGCTTCGACTTCATTATCCAGT
GGGAAGTTATCTACCGCTGGCTGTAAAAGCAGCTGATAGCCTTTCCCATCCGGCAGTCGGCGCGGGGTGA
AAGGAATAATGGCCGGTTTACCCATGCGCACCAGCAGATAAGTGCCGGTGGTGGTGGCGGCTTGATCAAC
GGCAAACAGCGGCACAAACACACTGCTGCCTGGGCCGTAATCATGGTCTGGTGCATACCAGATAATCTCA
CCCTGTTTAAGGCTGCGGATCATCCCTTTGAGATCTTTGCGATCCAGCATGGCTTTGTTGGAGCGCATCC
GGCCCCAAGTCTGCATCCAATCCATAGCTTTATTATCATGTGGCCGATAGACACCAATCCCTGGATTGTA
AATACCAAGAATACGCGCACCCAGTTCCAGCGTCAGAAAATGCAAACCTATTAACAACACCCCTTTACCT
TCATCGCGCGCTTTTTGGATATGTTCCAGCCCGCTAACACTGCACCAACGTTCAATGCGCCAATTAGGCC
AAAACCACGCCATCCCGGTTTCAAATAACCCCATACCGACGGATTCAAAATTCTTTAGCAGCAGTTCATC
TCGTTCACTTTTGGGCATATCCGGGAAACACAGTTCCAGATTGCGCTGCGTAATGCGCTTGCGTCGTTTA
AGAAATCGCATGGAAAAGCGGCCAAGGGAGGTGCCCAGGATATAAATCACTGGGTAGGGGAGTAGCACCA
GCAGGTAGAGAATACCGAGACCGAGCCAGGTCAGCCAATAACGAGGGTGAAGTAGTGAGCGATTAAAAGA
AGGAGCTTGCATATCTGTTTTCA
Protein Sequence 
>gi|123441919|ref|YP_001005902.1| lipid A biosynthesis lauroyl acyltransferase [Yersinia enterocolitica subsp. enterocolitica 8081] MKTDMQAPSFNRSLLHPRYWLTWLGLGILYLLVLLPYPVIYILGTSLGRFSMRFLKRRKRITQRNLELCFPDMPKSERDELLLKNFESVGMGLFETGMAWFWPNWRIERWCSVSGLEHIQKARDEGKGVLLIGLHFLTLELGARILGIYNPGIGVYRPHDNKAMDWMQTWGRMRSNKAMLDRKDLKGMIRSLKQGEIIWYAPDHDYGPGSSVFVPLFAVDQAATTTGTYLLVRMGKPAIIPFTPRRLPDGKGYQLLLQPAVDNFPLDNEVEAAAFMNKVVEKEIERATDQYMWLHRRFKTRPEGVPSLYE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: htrB mutant has diminished invasion of HeLa cells and is attenuated in vivo (Pérez-Gutiérrez et al., 2010).
COG COG1560M, under M: Cell wall/membrane/envelope biogenesis
References
Pérez-Gutiérrez et al., 2010: Pérez-Gutiérrez C, Llobet E, Llompart CM, Reinés M, Bengoechea JA. Role of lipid A acylation in Yersinia enterocolitica virulence. Infection and immunity. 2010; 78(6); 2768-2781. [PubMed: 20385763].