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ddhB

Victor ID 4025
Gene Name ddhB
Sequence Strain (Species/Organism) Yersinia enterocolitica subsp. enterocolitica 8081
NCBI Gene ID 4714573
NCBI Protein GI 123443294
Locus Tag YE3086
Genbank Accession AM286415
Protein Accession YP_001007268
Other Database IDs UniProtKB-ID: A1JNA2_YERE8
UniRef100: UniRef100_A1JNA2
UniRef90: UniRef90_A1JNA2
UniRef50: UniRef50_Q3KG52
UniParc: UPI0000EB5958
EMBL: AM286415
EMBL-CDS: CAL13121.1
RefSeq_NT: NC_008800.1
GenomeReviews: AM286415_GR
KEGG: yen:YE3086
NMPDR: fig|630.2.peg.3017
eggNOG: COG0451
HOGENOM: HBG755066
OMA: CYENREW
BioCyc: YENT393305:YE3086-MONOMER
Taxonomy ID 393305
Gene Starting Position 3355977
Gene Ending Position 3357050
Gene Strand (Orientation) -
Protein Name CDP-glucose 4,6-dehydratase
Protein pI 6.18
Protein Weight 37909.85
Protein Length 357
Protein Note Also known as rfbGPreviously sequenced to Yersinia enterocolitica CDP-glucose 4,6-dehydratase DdhB or RfbG SWALL:Q56861 (EMBL: U46859) (358 aa) fasta scores: E(): 6.2e-151, 99.16 id in 358 aa. Similar to Salmonella typhimurium CDP-glucose 4,6-dehydratase RfbG SWALL:RFBG_SALTY (SWALL:P26397) (359 aa) fasta scores: E(): 9.5e-109,69.66 38d in 356 aa.
DNA Sequence 
>gi|123440403:3355977-3357050 Yersinia enterocolitica subsp. enterocolitica 8081, complete genome
ATCATTTACTAGCCATATATTTATTAATTTCAACAATACTATATTCATGCATATTAACACCGCGTAACCA
CGCTTTATGCCATGCAACAATATATTCTAAAGTGCAATCTAGATTCCATCGAGACTGCCAGCCCAATAAA
ACCTTTGCTTTAGAACAATCCAGTTTTAGATAATTTGCCTCATGTGGATGTTCATGATCGTCTAACTGCC
AACAAGCATCTCCTCCCCAGTATTTTACCATTTTATCAACAATACTTTGTACTTGGCTAGAATCTGTGTC
ATCAGGGCCAAAATTCCAGCCTTCAGCATATTTAATTCCATCAATATATAATCGTTGAGCTAACAATAAA
TAACCTGACAAGGGTTCTAAAACATGCTGCCAAGGACGTATAGCATATGGATTCCGTATAATAACAGGCT
CAGAGTTCTCAAATGCGCGTAGCATATCTGGAACCACACGGTCTAAAGCCCAATCACCACCGCCAATAAC
ATTACCTGCACGTGCTGTCGCTAATGCTGTACCATGTTGTTCATATTTAACCGGATTAAAAAATGAATTT
CGATATGATGAAGTAACTAACTCGGCACAACCTTTACTATTTGAATAAGGATCATATCCCCCCATTGCTT
CGTCTTCACGATATCCCCAGACCCACTCTTTATTTTCGTAACATTTATCACTAGTTACATTAACAATAGC
CTTAGCTCCTCCTACATGTCGAAGAGCTTCCAACAAATAGACAGTACCCATAACATTTGTCGAATAAGTT
TCAACCGGTTCTAAGTATGACAACCGGACTAAAGACTGTGCAGCCATATGAAAAACGATTTCAGGTTTAA
AATCGTTGATTGACTTGAGTAGCTGAGCATAATTACGAATATCACCTACTTCCGAAATCATACCATCCGC
AACGTTGGCTGCTTCAAATAAACTTGGCTTTGTTGGTGCGTCCAAAGCATAACCTTTCACTTTGGCTCCC
ATATTTTGCAGCCATAAGCTCAGCCAACTACCTTTAAAGCCAGTATGGCCGGTGATAAAAACACGTTTGT
CTTGCCAAAATTTTTCATTAATCA
Protein Sequence 
>gi|123443294|ref|YP_001007268.1| CDP-glucose 4,6-dehydratase [Yersinia enterocolitica subsp. enterocolitica 8081]
MINEKFWQDKRVFITGHTGFKGSWLSLWLQNMGAKVKGYALDAPTKPSLFEAANVADGMISEVGDIRNYA
QLLKSINDFKPEIVFHMAAQSLVRLSYLEPVETYSTNVMGTVYLLEALRHVGGAKAIVNVTSDKCYENKE
WVWGYREDEAMGGYDPYSNSKGCAELVTSSYRNSFFNPVKYEQHGTALATARAGNVIGGGDWALDRVVPD
MLRAFENSEPVIIRNPYAIRPWQHVLEPLSGYLLLAQRLYIDGIKYAEGWNFGPDDTDSSQVQSIVDKMV
KYWGGDACWQLDDHEHPHEANYLKLDCSKAKVLLGWQSRWNLDCTLEYIVAWHKAWLRGVNMHEYSIVEI
NKYMASK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ddhB mutant is attenuated in mice (Darwin and Miller, 1999).
COG COG0451MG, under M: Cell wall/membrane/envelope biogenesis; G: Carbohydrate transport and metabolism
References
Darwin and Miller, 1999: Darwin AJ, Miller VL. Identification of Yersinia enterocolitica genes affecting survival in an animal host using signature-tagged transposon mutagenesis. Molecular microbiology. 1999; 32(1); 51-62. [PubMed: 10216859].