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pYV0094

Victor ID 3998
Gene Name pYV0094
Sequence Strain (Species/Organism) Yersinia pseudotuberculosis IP 32953
NCBI Gene ID 2952987
NCBI Protein GI 51593936
Locus Tag pYV0094
Genbank Accession BX936399
Protein Accession YP_068503
Other Database IDs UniProtKB-ID: YOPH_YERPS
UniRef100: UniRef100_P08538
UniRef90: UniRef90_P08538
UniRef50: UniRef50_P15273
UniParc: UPI00000D1266
EMBL: Y00551
EMBL: BX936399
EMBL-CDS: CAA68629.1
EMBL-CDS: CAF25437.1
RefSeq_NT: NC_006153.2
PDB: 1K46
PDB: 1M0V
PptaseDB: P3D0412161
GenomeReviews: BX936399_GR
KEGG: yps:pYV0094
HOGENOM: HBG299062
OMA: SAHEIAN
ProtClustDB: CLSK862151
BioCyc: YPSE273123:PYV0094-MONOMER
Taxonomy ID 273123
Plasmid No pYV
Gene Starting Position 64365
Gene Ending Position 65771
Gene Strand (Orientation) -
Protein Name yopH; putative protein-tyrosine phosphatase Yop effector
Protein pI 8.84
Protein Weight 47198.12
Protein Length 468
Protein Note similar to Y. pestis YPCD1.67c
DNA Sequence 
>gi|113911685:64365-65771 Yersinia pseudotuberculosis IP 32953 plasmid pYV, complete sequence
ATTAGCTATTTAATAATGGTCGCCCTTGTCCTTCAGCCAACTTAATCAGAACATCAAGTTGCTCATCTTT
TTGTACCATAATACCATTTCTTTGTACTCGCATTTGGCTGACCATATCTTCTACGCTTAACTGACTATTA
CGACTATCATTCATGCACATTGCGCCAATCAGTTGCGCAGTACGGCCAACACCCGCACGGCAATGTATTA
CCGGCCGTAATTTGGAGTCATCTCCTACCGCTGAACTTCCTTTGCTTTCATACATATTGCGTTTTGTTTC
TGCTGTTTGATCTACCAGTGAAGCGAGTGCCTTGGTAACTTCAGAGCTGACTGCGGTCTGATCGGGCCAA
TTGCCAACATGAACCACAGGAACAGAGATTGTTTTTTGACCCGCTTCACGAATCGTTAAAGTATACATAT
CTGCCATAATCCCGTCACCGAGACCAACTTGCTGAGTCATTTTAGACTCTACAGTGATACTGCCATAGGT
ACCACTCTGGCGGAAATAATCTGGCATACCGAATCTTTGATTGGCTATCTCAGAACTGGACGCTAAAACA
GCCAACACTGGCGTTCGGTTTTCTGCCAGCATACGGAAATGGCTTTCAAGTTGAGATTGTAGCGGATACT
GGCACGCTATGGTACGAGTGTTACCGACCTGGATGTAATTGGCATTAAGATCGGCGCGTACTGCGGTTTG
CCGACAGCATTGAATATCTCTAAATCGGTTTAGCTTTTCACCGCCGCAGGCTTGTAAGTAACGCGGATCA
TTCGTTGCTGGCGCCAGCGTATTGCGCAATGTGGTGAGGCGGCTGCTGAGTTCTGCGCGCGCTTCTGGGC
CATAAGGAGAAACAGTGCTTGGTGCGGTGGCTCTGGCTTCGCCAGCCCCGTGATGGCCAGAAGTGTGTGG
TCGTTCACGCGGTGGCAACGGTGGAGTTCTGGGGTCTAGATGTGAACGCAGTCCTTCACGCACCGGGGTT
CCCGGTGCGTGAAGGGCTGAATGTGAATGAGATGATACATGCCCCCTCGCTCCCGACTCTTGTCGCAATG
CGGCCTCCAACAGCACTTTGGCGTCTTGTAGTGTCATTTGGTCACTACGTAAACTGACAAGTACACTATT
ACCATTGCCGACACTTCTTAAGTCATAATTATTCAAATTATGCTTTACCGTACTTTGCAATAGCTTAGCG
GTATCTTCTTGAGTTAGAACAACATTTGCTACGTGGCTTAGTACAGTTTGAGCAAATACTTTTTCTGACT
CTCTGGCACCACTGGCTATGGTCAAACCTTGAAAGGTAGTTTCTTTATTGGCAGCAACGTTACCTCTTAA
TTTCCCGGTACAATCACCGCTCTCTTGCTGCACCAATCGAGATACCTGACGATGAAGATCGCTTAATGAT
AAGTTCA
Protein Sequence 
>gi|51593936|ref|YP_068503.1| yopH; putative protein-tyrosine phosphatase Yop effector [Yersinia pseudotuberculosis IP 32953]
MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANVVLTQ
EDTAKLLQSTVKHNLNNYDLRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSALH
APGTPVREGLRSHLDPRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAP
ATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTP
VLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVH
VGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVGDDSKLRPVIHCRAGVGRTAQLIGAMCMN
DSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopH mutant is attenuated in mice (Deleuil et al., 2003).
COG COG5599T, under T: Signal transduction mechanisms
References
Deleuil et al., 2003: Deleuil F, Mogemark L, Francis MS, Wolf-Watz H, Fällman M. Interaction between the Yersinia protein tyrosine phosphatase YopH and eukaryotic Cas/Fyb is an important virulence mechanism. Cellular microbiology. 2003; 5(1); 53-64. [PubMed: 12542470].