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pYV0047

Victor ID 3995
Gene Name pYV0047
Sequence Strain (Species/Organism) Yersinia pseudotuberculosis IP 32953
NCBI Gene ID 2952940
NCBI Protein GI 51593889
Locus Tag pYV0047
Genbank Accession BX936399
Protein Accession YP_068456
Other Database IDs UniProtKB-ID: Q663L9_YERPS
UniRef100: UniRef100_Q663L9
UniRef90: UniRef90_B2KAJ9
UniRef50: UniRef50_P17778
UniParc: UPI0000426FB2
EMBL: BX936399
EMBL-CDS: CAF25390.1
RefSeq_NT: NC_006153.2
GenomeReviews: BX936399_GR
KEGG: yps:pYV0047
NMPDR: fig|273123.1.peg.43
HOGENOM: HBG758074
OMA: VRENDLT
ProtClustDB: CLSK862120
BioCyc: YPSE273123:PYV0047-MONOMER
Taxonomy ID 273123
Plasmid No pYV
Gene Starting Position 33231
Gene Ending Position 34883
Gene Strand (Orientation) -
Protein Name yopM; putative targeted effector protein
Protein pI 4.12
Protein Weight 59850.25
Protein Length 550
Protein Note similar to Y. pestis YPCD1.26c
DNA Sequence 
>gi|113911685:33231-34883 Yersinia pseudotuberculosis IP 32953 plasmid pYV, complete sequence
ACTACTCAAAAACATCATCTTCAAGTTTGTCTGTAGTCTCATGAGCAAATTCATATGGATCAACTACACG
TTCAGAGTCCATCTCAAGCTCTTCCAATGACTCAGGTATATCGGGAAACTCTCTCAGAGCGTTTTGCTCT
ACGTGGAGCTGTTTCAGGTTTTGCGGCAATTCAGGTACTTCAGCAAGATAATTAAATGAAGCGATTAAAC
GTTCTAAGTGTGGAGGTAACGCTGGCAGTTCGCTCAACTGATTACTTTTGACATTAAGGTCTACCAGTGA
AGGAGGTAAATCGCATAAGGATCTTATTTCATTGCTGGATGCATCGAGATAATACAAGTTTGGTGGCAAT
TCCGATAATCCAGAAATATTATTATCAGAAACATCTAAGAAGGTTAAACTCTGCGGTAATTCTGGCAGAT
CAGTTAAATCATTTTCTCTGACATGAAGTTTTTTCAGGGAAGGGGGTAAATCGGGTAATGTTTCCAGTAA
ATTGTTATCAGCATAAATCGCAGCCAAGAAGGGCAAGTTTTGCAACTCTGGTAATTCTTCCAGCTTATTA
CTACTAGCAGTAAGATATTCCAGTGAAGGAGGTAAATCGGATAATGCCTTCAGATTGTTATTATCAACTC
GAAGTGATTTCAGGCTCTGCGGCAATTCCGGTAATTCAGTAAGAGAATTATATGACGCCACTAAAATCTC
TAAATGCGGGGGTAAATCGGGTAATGTTTCCAGTAAATTGTTATCAGCATAAATCGCAGCCAAGAAGGGC
AAGTTTTGCAACTCTGGCAATTCTTCCAGCTTATTACTACTAGCAGTAAGATATTCCAGTGAAGGAGGTA
AATCGGATAATGCCTTCAGATTGTTATTATCAACTCGAAGTGATTCCAGGCTCTGCGGTAATTCTGGCAG
ATCAGTTAAATCATTTTCTCTGACATGAAGTTTTTTCAGGGAAGGGGGTAAATCGGGTAATGTTTCCAGT
AAATTGTTATCAGCATAAATCGCAGCCAAGAAGGGCAAGTTTTGCAACTCTGGCAATTCTTCCAGCTTAT
TACTACTAGCAGTAAGATATTCCAGTGAAGGAGGTAAATCGGATAATGCCTTCAGATTGTTATTATCAAC
TCGAAGTGATTCCAGGCTCTGCGGTAATTCTGGCAGATCAGTTAAATCATTTTCTCTGACATGAAGTTTT
TTCAGGGAAGGGGGTAAATCGGGTAATGCCTTCAGATTGTTATTTTCAACTTGAAGTGATTTCAGGCTCT
GCGGCAATTCCGGTAATTCTGTAAGAGAATTACATGACGCCACTAAACTCTCTAAATGCGGAGGTAATTC
CGGCAAAGAACTCAGCCCCAGATTATTTAGTTCTAGCTCATGGGCTTGTCGGTCCAGGCAATCTCGTAAC
CTTGAAACCGCCATTTCCCTCTGTTCACCATTCCCCGGAGGGGCATTTCGTTCCCATTCCGACCATGCAT
TATAATATTCAGTCTTAGATTTAACATTTTCTGCCTCAACCGGCATCTCAGTTAAATTAGAAGAATGACG
TAATGGTTCTTGCAAAAAAGTATTAGATACATTTCTTGGATTTATGAACATATTGAATGCCTTTCTGAAA
ATATTTTTATTATCGAGTTTTTCACTGCAAACAAAACCATACA
Protein Sequence 
>gi|51593889|ref|YP_068456.1| yopM; putative targeted effector protein [Yersinia pseudotuberculosis IP 32953]
MYGFVCSEKLDNKNIFRKAFNMFINPRNVSNTFLQEPLRHSSNLTEMPVEAENVKSKTEYYNAWSEWERN
APPGNGEQREMAVSRLRDCLDRQAHELELNNLGLSSLPELPPHLESLVASCNSLTELPELPQSLKSLQVE
NNNLKALPDLPPSLKKLHVRENDLTDLPELPQSLESLRVDNNNLKALSDLPPSLEYLTASSNKLEELPEL
QNLPFLAAIYADNNLLETLPDLPPSLKKLHVRENDLTDLPELPQSLESLRVDNNNLKALSDLPPSLEYLT
ASSNKLEELPELQNLPFLAAIYADNNLLETLPDLPPHLEILVASYNSLTELPELPQSLKSLRVDNNNLKA
LSDLPPSLEYLTASSNKLEELPELQNLPFLAAIYADNNLLETLPDLPPSLKKLHVRENDLTDLPELPQSL
TFLDVSDNNISGLSELPPNLYYLDASSNEIRSLCDLPPSLVDLNVKSNQLSELPALPPHLERLIASFNYL
AEVPELPQNLKQLHVEQNALREFPDIPESLEELEMDSERVVDPYEFAHETTDKLEDDVFE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: yopM mutant has attenuated colonization of mouse tissues (McCoy et al., 2010).
COG COG4886S, under S: Function unknown
References
McCoy et al., 2010: McCoy MW, Marré ML, Lesser CF, Mecsas J. The C-terminal tail of Yersinia pseudotuberculosis YopM is critical for interacting with RSK1 and for virulence. Infection and immunity. 2010; 78(6); 2584-2598. [PubMed: 20368345].