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bscN

Victor ID 3968
Gene Name bscN
Sequence Strain (Species/Organism) Bordetella pertussis Tohama I
NCBI Gene ID 2667132
NCBI Protein GI 33593244
Locus Tag BP2245
Genbank Accession BX640417
Protein Accession NP_880888
Other Database IDs UniProtKB-ID: Q84CR7_BORPE
UniRef100: UniRef100_Q84CR7
UniRef90: UniRef90_O68539
UniRef50: UniRef50_P80153
UniParc: UPI00000337BF
EMBL: Y13383
EMBL: BX640417
EMBL-CDS: CAC79575.1
EMBL-CDS: CAE42520.1
RefSeq_NT: NC_002929.2
HSSP: P03002
GenomeReviews: BX470248_GR
KEGG: bpe:BP2245
NMPDR: fig|257313.1.peg.1962
HOGENOM: HBG565875
OMA: KLANDHV
ProtClustDB: PRK06936
BioCyc: BPER257313:BP2245-MONOMER
Taxonomy ID 257313
Gene Starting Position 2370831
Gene Ending Position 2372165
Gene Strand (Orientation) -
Protein Name type III secretion system ATPase
Protein pI 6.86
Protein Weight 43987.38
Protein Length 444
Protein Note Similar to many eg. Bordetella bronchiseptica BscN TR:O68539 (EMBL: AF049488) (444 aa) fasta scores: E(): 2.6e-162, 99.32% id in 444 aa, and to Pseudomonas aeruginosa ATP synthase in type III secretion system pa1697 TR:Q9I330 (EMBL: AE004596) (440 aa) fasta scores: E(): 1.8e-103, 68.19% id in 415 aa
DNA Sequence 
>gi|33591275:2370831-2372165 Bordetella pertussis Tohama I, complete genome
ATTAGGATTCGGGTCCGATGATTTCAGCCATGCGCAGTACGGTATCCTCGAATGCTTCGCGTTCGTCGGT
TAGTTGTCTGAGAAACGCATTGATCTGTCCGATCTTCTGTATCGCCTCATCGGTCGACGCATCGGCGCCC
TGCTTGTACTCGCCGATTTTCACCAACAGCTCGACATCCTGGTACTTGGCCATCAGTTCGCGCATACGTC
CGGCCAGGTACTTGTGACGCGGCGACACCACGGCATTCATGACCCGGCTGGCCGAGGCCAGCACGTCGAC
GGCAGGATAGTGATTCGCCGCTCCCAGCTTGCGCGAGAGCACGATGTGGCCGTCCAGTATCGAACGCGTC
TCGTCGGCCACCGGTTCGTTCATGTCGTCCCCCTCGACCAGCACCGTATACAGCGCCGTGATCGAACCCG
TCTGGTTCATGCCGGCGCGCTCCATCAGTTTGGGCAAGGTGGCGAACACCGACGGTGGATAGCCGCGCCG
CGTCGGCGGCTCGCCTGCCGCCAAGCCGATTTCACGCTGGGCTCGCGCAAAGCGGGTGACCGAGTCCATC
AGAAAAAGTACACGCTGCCCTTGATCGCGGAAGTATTCGGCGATGGCGGTTGCGACGTACGCCGCCTTGG
CACGCTCCATCGAGGACTTGTCGCTGGTCGCGCAGACGATCACGCTCTTGCGTCTGCCCTCCGGACCGAG
TTCGTGCTCAAGGAACTCGCGAACTTCCCGCCCACGCTCGCCGATCAGCGCCACCACCGTCACGTCGACC
GCGGCGCCCTTGACCAGCATGCCCAGCAGGGTCGACTTGCCGCCGCCGGCGGCTGCGAAAATTCCCAGAC
GCTGGCCTTCCCCGCATGTAAGCAAACCGTCCAGTACGCGCACCCCCAGCTCCAGCGGAGCATGGATGAT
GCGACGCGTCAGCGGGTCTGGCGCATCGGCGAAGACCGGATAGAACTTGTGGGCATGCAGCGGCCCTGAC
TCGGCGGCGTCCAGCGGACGTCCCAGCCCGTCCAGCACGCGTCCCAGCAAGCCCGGACCGACGGGGACCA
TATGCGTGCGTCCGGTCGGTATCACCTCGGTCGCCGAGGAAATCCCGTACATGTCGCCGATAGGCGTGAG
CAAGGCGGCGTCGCGGACAAAGCCCACCACTTCGCCGTGCATCTCGAAGTCCTCGCCGGGATTGCGCAGC
AGGCACACTTCGCCGATCTTGACCATCGGAACGACGGCCTTGATGATCGTTCCCACCACTTGCACCACCC
GGCCCTTTATCCGCAGCGTGGACAGATCCTGCAGGGCCACCCGCATCATCTCCGTGATGTAGTGGTACTG
ACGCA
Protein Sequence 
>gi|33593244|ref|NP_880888.1| type III secretion system ATPase [Bordetella pertussis Tohama I]
MRQYHYITEMMRVALQDLSTLRIKGRVVQVVGTIIKAVVPMVKIGEVCLLRNPGEDFEMHGEVVGFVRDA
ALLTPIGDMYGISSATEVIPTGRTHMVPVGPGLLGRVLDGLGRPLDAAESGPLHAHKFYPVFADAPDPLT
RRIIHAPLELGVRVLDGLLTCGEGQRLGIFAAAGGGKSTLLGMLVKGAAVDVTVVALIGERGREVREFLE
HELGPEGRRKSVIVCATSDKSSMERAKAAYVATAIAEYFRDQGQRVLFLMDSVTRFARAQREIGLAAGEP
PTRRGYPPSVFATLPKLMERAGMNQTGSITALYTVLVEGDDMNEPVADETRSILDGHIVLSRKLGAANHY
PAVDVLASASRVMNAVVSPRHKYLAGRMRELMAKYQDVELLVKIGEYKQGADASTDEAIQKIGQINAFLR
QLTDEREAFEDTVLRMAEIIGPES
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion mutant showed a decrease in cytotoxicity and secretion of proteins in vitro as well as reduced colonization in the trachea of a rat infection model (Yuk et al., 1998).
COG COG1157NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Yuk et al., 1998: Yuk MH, Harvill ET, Miller JF. The BvgAS virulence control system regulates type III secretion in Bordetella bronchiseptica. Molecular microbiology. 1998; 28(5); 945-959. [PubMed: 9663681].