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bvgA

Victor ID 3966
Gene Name bvgA
Sequence Strain (Species/Organism) Bordetella pertussis Tohama I
NCBI Gene ID 2667058
NCBI Protein GI 33592926
Locus Tag BP1878
Genbank Accession BX640416
Protein Accession NP_880570
Other Database IDs UniProtKB-ID: BVGA_BORPE
UniRef100: UniRef100_P0A4H3
UniRef90: UniRef90_P0A4H3
UniRef50: UniRef50_P0A4H3
UniParc: UPI0000126B5D
EMBL: M25401
EMBL: BX640416
EMBL-CDS: AAA22969.1
EMBL-CDS: CAE42161.1
RefSeq_NT: NC_002929.2
GenomeReviews: BX470248_GR
KEGG: bpe:BP1878
HOGENOM: HBG753323
OMA: HENLHEV
ProtClustDB: CLSK434910
BioCyc: BPER257313:BP1878-MONOMER
Taxonomy ID 257313
Gene Starting Position 1967724
Gene Ending Position 1968353
Gene Strand (Orientation) -
Protein Name virulence factors transcription regulator
Protein pI 8.69
Protein Weight 21265.01
Protein Length 209
Protein Note Previously sequenced as Bordetella pertussis virulence factors putative positive transcription regulator BvgA bvgA SW:BVGA_BORPE (P16574) (209 aa) fasta scores: E(): 3e-77, 100% id in 209 aa
DNA Sequence 
>gi|33591275:1967724-1968353 Bordetella pertussis Tohama I, complete genome
GCTAGGCGAGATTGTTGCGTTTGGCGAGGTCTATCAGTTCCACCAGCGACGTGGCGTTCAGCTTCTGCAG
CAGGCGCGTCTTGTAGGTGCTGACGGTCTTGTTGCTGAGGAACATGCTGTCAGCGATGTCCTTGTTGGAC
ATGCCTTGCGCCAGCAGTTGCAGGACGGTCAGTTCGCGGTTGGACAACACGCTGATGAGCGTACTGTCGC
TCTTGGCGTTGTCGCCCATGCGCATCTCGCTGAGCGTGGTGCTGGGGAAGTAGGTGTAGCCGGCCATCAC
CGCCTTGGCGGCATTGATGACCTCGTGCAGGTTCTCGTGTTTGCACACGAAGCCTGCGGCGCCGGAGTTC
AGGCAGCGGCGGGCGAACAGCGAAGGCGGCTGGCCGGTCAGCACCAGCACGCGTAGCGGCAACCCCAGCG
ATTGCAGCCGGGCGATGACTTCCAGCCCGTCCAGCTTGGGAATGCCGATGTCGAGTACGACGAGGTTGGG
AATTTTCTCGCGGGCGATCTTGAGCCCGTCAATGCCGTTATCGGTTTCGCCGATGACTTCGAATCCTTCC
TTTTCCATCAGGACCCGGACGGCGAATCTCAGTACAGGGTGATCGTCAATGATGAGGACTTTGTTGTACA
Protein Sequence 
>gi|33592926|ref|NP_880570.1| virulence factors transcription regulator [Bordetella pertussis Tohama I]
MYNKVLIIDDHPVLRFAVRVLMEKEGFEVIGETDNGIDGLKIAREKIPNLVVLDIGIPKLDGLEVIARLQ
SLGLPLRVLVLTGQPPSLFARRCLNSGAAGFVCKHENLHEVINAAKAVMAGYTYFPSTTLSEMRMGDNAK
SDSTLISVLSNRELTVLQLLAQGMSNKDIADSMFLSNKTVSTYKTRLLQKLNATSLVELIDLAKRNNLA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant strain showed growth inhibition and reduced colonization (Stibitz, 1998).
COG COG2197TK, under T: Signal transduction mechanisms; K: Transcription
References
Stibitz, 1998: Stibitz S. Mutations affecting the alpha subunit of Bordetella pertussis RNA polymerase suppress growth inhibition conferred by short C-terminal deletions of the response regulator BvgA. Journal of bacteriology. 1998; 180(9); 2484-2492. [PubMed: 9573202].