Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

bvgS

Victor ID 3965
Gene Name bvgS
Sequence Strain (Species/Organism) Bordetella pertussis Tohama I
NCBI Gene ID 2667057
NCBI Protein GI 33592925
Locus Tag BP1877
Genbank Accession BX640416
Protein Accession NP_880569
Other Database IDs UniProtKB-ID: BVGS_BORPE
UniRef100: UniRef100_P16575
UniRef90: UniRef90_P26762
UniRef50: UniRef50_P16575
UniParc: UPI00001B71B8
EMBL: M25401
EMBL: BX640416
EMBL-CDS: AAA22970.1
EMBL-CDS: CAE42160.1
RefSeq_NT: NC_002929.2
GenomeReviews: BX470248_GR
KEGG: bpe:BP1877
NMPDR: fig|257313.1.peg.1645
HOGENOM: HBG640045
OMA: CTADARE
ProtClustDB: CLSK920529
BioCyc: BPER257313:BP1877-MONOMER
Taxonomy ID 257313
Gene Starting Position 1963999
Gene Ending Position 1967715
Gene Strand (Orientation) -
Protein Name virulence sensor protein
Protein pI 6.01
Protein Weight 125773.68
Protein Length 1238
Protein Note Previously sequenced as Bordetella pertussis virulence sensor protein BvgS precursor bvgS SW:BVGS_BORPE (P16575) (1238 aa) fasta scores: E(): 0, 99.83% id in 1238 aa
DNA Sequence 
>gi|33591275:1963999-1967715 Bordetella pertussis Tohama I, complete genome
TTCAGGGCTGATCTTGATGCGGCCGTTGCTCCAGCCAGGCGCGCAGTTGCGTCTCCAGCGCGGCGGACTG
CGCCGCAAGCGTACGTACCAGGCCGTCGATTTCGGGTGAGGGGCCAGCCTGGCCTTGCGCTTTTTTCTCC
AGCGCCAGCACAGTGTCTATCATGGCCTTGGCATCGACCACGCGCGCGCCGCCGGCCAGCCTGTGCGCCA
TGTCCGAGACCTTCGGCCAATCGGCCTGCTGGTGCAGCTTTTGCAATTGGTCGACGTCCGCCCGGTTGGT
GCGAATCACTTCTTCGAGCAATTGCCGGATCAGCGCCTCATCGTTCTGCGTCAAGGCAAGAATCGACTCG
GCCGAGAACGCCGTCGGGGTGGCGTCGTCCGTGGCCGGCGCGGCAGCCTGGGGCGAGGGGGGCGTGGGGA
GCGCGGCCCGTGCCACGGCTTCGTTCAAGCGTTGCCGCAAGGCGTCCACGCCGATCGGCTTGAACAGGCA
GTCGTCCATGCCGGCGGCGCGGCAGCGCTGCGCTTCGTCCATCTGCGCCGAAGCCGTGAAGCCGAACAGA
ATGCACCGCGTACGTCCGTAACCGGGCGCGGCCTCGGCGGCGCGTATGCGGCGCGCCAATTCGTAGCCGC
TGATACCGGGCATGTTGCAATCGGTGATCACGACGTCGAACGCATGCTCGCGCCACAGGGCCAGGGCGGC
TTCGCCGGAGTCGGCGGCGATGACACGCTGGCCCAGGTAGTCCAGCTGCTGGCGCAGCAGCATCAGGTTG
GGTTTGTGGTCATCGACGACCAGCACGCGCAGCGATACCTGCGGCTTGGACGGCGTGGCCGCAGTGGCCG
CAGCGGGCGGCGCGGCCTGCACGGATTTTTCGACCATGGTCAGCCTCAGGTCCACCGAAACCGTTGTGCC
CACCCCTGGCGCGCTGCGCATGACCAGCGTTCCCCCCATCAATTCGACGAGGCGCCGGCTGATGGACAGG
CCCAGGCCGGTGCCCGGCGCCGGCCCGGCCTCGGCGCTGCCACCCACTTGCGAGAACGGTTTGAACAGCT
GCCGTTGGTCGGCCTCGCTGATGCCGCAGCCGGTGTCGCTCACGCTGAACTGCACGTGCGCGGCGTCGCC
GTCGGGGCGTGCGGTCACGGCAAGGACAACCTGGCCTTCGGTGGTGAACTTGATGGCGTTGCCCACCAGG
TTCGAGAGCACTTGCTTCATGCGCAAGGGGTCTATCAATACATCGTCGACGCCCACGATGTCGGTCTTCA
ATACCAGCTCTATGCCTTTTTGGCGCGCCAATCCGTCGAAGACGCGGATCGCCCCTTCGGGCAGGACGCG
CAGCGCCGTGCGCACCGGCGCCAGGTCGAATTTTCCCGCCTCGATCTTCGCAATGTCCAGGATGTCGCCT
ATCAGCTCCAGCAGGCTGCGGGCCGAGTCGTACGCGACCTGGATGGACTGGCGATCCGGCTCCTGGTCGG
TCGGACGGAGCAGCGCCAGCTCCAGCATGCCGATGATCGCGTTCATCGGCGTGCGGATCTCGTGGCTCAT
CGTTGCCAGGAACGTGGTCTTGGCCCGGTTGGCGGCGTCGGCGCTTTCCTTGGCGTCGTGCAGCTTGCGC
AGCAGCTCGGCGCGTTCGGTGATGTCGATCCAGCCGCCGATGATGCCCTTGAGTTCGCCCAGCGAGTCGC
CGTACGGAATCGTCCACTGGTAGACATGGCGGGTGCGGCCGTGCAGCGTGACATCGCGGTCCTCGAAGCG
CGGCTCGCGCTCGGCGGCCACGCGCGTGAGCAGGAACTCGTGCATTTCGCGGGCCAGCGCCGGGTCGCCC
ACCACGTTGGCTTCCGGAATGGTCTTGCCCAGTACCGCATCGGCAGTCACGCCAAAGGTGTCGAGGTAGG
CGTCATTGCACAACAGCATGCGGCCTTCCTTATCGCGCACATAGATGGGGTTAGGCGTGCCGTCGATGAG
CACGCGCATGAATTCCAGCTGGTCGTTCAGCGCCCGCTCGGCCCGCTTGCGCTGGCGGATCTGGCGCCGC
AGGTAGACGATCCAGCTCAGGAACAGCAGGGCCGACAACAGGCCCAGCCCGATCAGCAGGTAGATCTCGT
TGCGGTAGGCGTACCAGGTGCGCGGATCGCCGTCGCTGCCGCGCCAGCGGCTGATGATGGAGGCGAGCTC
GTCGTTCGAAATGCTGTAGAGCGCCTTGTTCAGGATGGACATCAGTTCGGTCTGGCCGCGCGTCGTCGCC
AGCGCGATCTCGGCCGGGGGCAGGTCCAGCGCCGAGGCGATGCGCAGCTTGCCGGCGAAGTAGCGGTTGA
CGTAATAGCTGGCGCTGATCTGCGTCTGCACGACGGCGTCGGCCTGTCCATTGGCCACCATCAGCATCGC
CTCGCTCGGGTTGTCGGCGGTCACCACCTTCGCCTGGGGATAGCGCCGCTGCAGCAGGGGAATGGCGGCG
CTGTTGCGCACCAACGCGACCGTGCGGCCGTCCAGATGATCGGCGTCGACGGGCGCGTCGGGGTCCTGGC
GCGTGACGATCACCATGCCATTGCGCACATACGGCCGGCTGAAACTGAGGAAGGACTCCCGCGCGCTGTT
GACGAACAGGGCGCCGGCCATGTCGGCTTCGCCCGAACGCAGCTTGGCTATCAGTTCCTCGACCGTGTCG
ACGCCGATGATCTCGAAGTCCAGGCCGGTGCGCAATTGCAGCAGCTGCAGCACGGCGGCGCTGATCCCGC
CGAACTGTTCGTCGGTGCGGAACAGGGTGAAGGGCGCGAACAGATTCAGGACCGCCACCTTGACGACGGG
GTGGTCTGCCATCCATTGCTGCTCGCGCGCGGAATACGCGGGGTGCGCGAAATCGAGCGAAATGCTGCTG
CCCAGTCCCCAGCGGTAGATCAGGCTGCGGTGTTCGGAAGGCGGAATGGCTTCGAGTACGGCGTTGACCA
CCCGCAGCAGGCGGGTGTTGTCGGCGCGCACGCCGAAGGATTCTCCGCCCGTCGCGATATGGGCCGGGGC
GACTACGCGAACGTCATTGAAATAGCTTTGCGATACGAGGTGCGAGGTGGTCAGGGCATCGCCGATGAAT
ACGTCGGCCTGCCCATAGGCCACCGCGGCCAGCGCCTGCTCGGATGAGGGGAAGTAATGCAGCGTAGCCT
GCGGGTAGGCCCGTGCGAGCGTTTCCTTGGGCAGGTAGTTGATGTCGACCGCCAGCCGCTGGCCGGCCAG
GTTCGAGGCTGGAACGTGGCGTGCGCCGATGGGCATGACGATCACCGGGTGGTCGGCGGCGTAGGGAACG
CTCAGACGCAGGCTCTGTTGCCGGCCGTCCGTGCCATTGACGGTGCCGATGAGGTCGATCTGCCCGCTTT
CCAGCGCGCTGAGGGCTTGTTCGCGCGTGGGGTATCGCAGCACTTTCGCCTGCATCCCCAGGTTGTGCGC
GATGATCGCCATGTAGTCGGCCGTCAGGCCTTCGTAGCGTTCGCCATAGGTGACGTCGAACGGAGGAATG
TCCGGTGCGTACACACCCAGCGTCAGTACCCGCTTGCGGGCCAGCCAACGCCAGTCGTCGCCGTCGAGCG
CGACCTCGACGTCGGGAACGGCAGCCTTGCCGACCAGGGTCAGCTCCTGGCTTGCCTGCGCGGGCGCCCA
TGCCAGCAAAGCCCATGCCAATAGCGCCTGAGCCAGGCAGATCAGACTGCGGGGGTACAGGCGGTGCGGG
GCGGGCA
Protein Sequence 
>gi|33592925|ref|NP_880569.1| virulence sensor protein [Bordetella pertussis Tohama I]
MPAPHRLYPRSLICLAQALLAWALLAWAPAQASQELTLVGKAAVPDVEVALDGDDWRWLARKRVLTLGVY
APDIPPFDVTYGERYEGLTADYMAIIAHNLGMQAKVLRYPTREQALSALESGQIDLIGTVNGTDGRQQSL
RLSVPYAADHPVIVMPIGARHVPASNLAGQRLAVDINYLPKETLARAYPQATLHYFPSSEQALAAVAYGQ
ADVFIGDALTTSHLVSQSYFNDVRVVAPAHIATGGESFGVRADNTRLLRVVNAVLEAIPPSEHRSLIYRW
GLGSSISLDFAHPAYSAREQQWMADHPVVKVAVLNLFAPFTLFRTDEQFGGISAAVLQLLQLRTGLDFEI
IGVDTVEELIAKLRSGEADMAGALFVNSARESFLSFSRPYVRNGMVIVTRQDPDAPVDADHLDGRTVALV
RNSAAIPLLQRRYPQAKVVTADNPSEAMLMVANGQADAVVQTQISASYYVNRYFAGKLRIASALDLPPAE
IALATTRGQTELMSILNKALYSISNDELASIISRWRGSDGDPRTWYAYRNEIYLLIGLGLLSALLFLSWI
VYLRRQIRQRKRAERALNDQLEFMRVLIDGTPNPIYVRDKEGRMLLCNDAYLDTFGVTADAVLGKTIPEA
NVVGDPALAREMHEFLLTRVAAEREPRFEDRDVTLHGRTRHVYQWTIPYGDSLGELKGIIGGWIDITERA
ELLRKLHDAKESADAANRAKTTFLATMSHEIRTPMNAIIGMLELALLRPTDQEPDRQSIQVAYDSARSLL
ELIGDILDIAKIEAGKFDLAPVRTALRVLPEGAIRVFDGLARQKGIELVLKTDIVGVDDVLIDPLRMKQV
LSNLVGNAIKFTTEGQVVLAVTARPDGDAAHVQFSVSDTGCGISEADQRQLFKPFSQVGGSAEAGPAPGT
GLGLSISRRLVELMGGTLVMRSAPGVGTTVSVDLRLTMVEKSVQAAPPAAATAATPSKPQVSLRVLVVDD
HKPNLMLLRQQLDYLGQRVIAADSGEAALALWREHAFDVVITDCNMPGISGYELARRIRAAEAAPGYGRT
RCILFGFTASAQMDEAQRCRAAGMDDCLFKPIGVDALRQRLNEAVARAALPTPPSPQAAAPATDDATPTA
FSAESILALTQNDEALIRQLLEEVIRTNRADVDQLQKLHQQADWPKVSDMAHRLAGGARVVDAKAMIDTV
LALEKKAQGQAGPSPEIDGLVRTLAAQSAALETQLRAWLEQRPHQDQP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant displayed reduced virulence, and lost ability to express some Bvg+-phase factors (Cotter and Miller, 1997).
COG COG0642T, under T: Signal transduction mechanisms
References
Cotter and Miller, 1997: Cotter PA, Miller JF. A mutation in the Bordetella bronchiseptica bvgS gene results in reduced virulence and increased resistance to starvation, and identifies a new class of Bvg-regulated antigens. Molecular microbiology. 1997; 24(4); 671-685. [PubMed: 9194696].