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BP3072

Victor ID 3961
Gene Name BP3072
Sequence Strain (Species/Organism) Bordetella pertussis Tohama I
NCBI Gene ID 2666331
NCBI Protein GI 33593999
Locus Tag BP3072
Genbank Accession BX640420
Protein Accession NP_881643
Other Database IDs UniProtKB-ID: Q7VUL4_BORPE
UniRef100: UniRef100_Q7VUL4
UniRef90: UniRef90_Q7W201
UniRef50: UniRef50_Q1LC37
UniParc: UPI00001B757B
EMBL: BX640420
EMBL-CDS: CAE43341.1
RefSeq_NT: NC_002929.2
GenomeReviews: BX470248_GR
KEGG: bpe:BP3072
NMPDR: fig|257313.1.peg.2715
HOGENOM: HBG730280
OMA: FGRMAYT
ProtClustDB: PRK08905
BioCyc: BPER257313:BP3072-MONOMER
Taxonomy ID 257313
Gene Starting Position 3274233
Gene Ending Position 3275087
Gene Strand (Orientation) +
Protein Name lipid A biosynthesis lauroyl acyltransferase
Protein pI 10.81
Protein Weight 29432.08
Protein Length 284
Protein Note Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA
DNA Sequence 
>gi|33591275:3274233-3275087 Bordetella pertussis Tohama I, complete genome
GATGCTCGTCACCCTGTTACGTATGGCCGCGGCCCTGCCGCTGCCGTTCCTGCATGCGGCCGGCCGGCTG
CTGGGACGGCTGGCGTATGCCTTTCCCGGCAAATACCGCGACCGCCTGCGGGCCAATGCCGCCCAGGCCG
GCTATCCCCAGCCCGCCTTCGCCCGGCGCGCCGCCGGCGAAATCGGGGCCATGATCCTGGAAATGCCCAA
GGTGTGGTTTCGCAACGAACAAAGCCTGGGAAAAGTGGTGTCGGATGACTACGCCATCGTCGAGGCGGCG
CGCGCCGAGGGGCGCGGCATCCTGTTCCTGACGCCGCACCTGGGCTGCTTCGAAATCACCGCGCGCTACC
TGGCGCGCCAGATGCCCATGACGGTGATGTTCCGCCCACCGCGCAAGGCCGCGCTGGCCCCGGTACTGGA
GACGGCGCGCAACACCTCGGCGGTCAACGCCGTGCCCGCCACCATGCAGGGCGTGCGCACCCTGCGGCGC
GGCGAGTCGGTGGGCATGCTGCCCGACCAGGCGCCGGGCGTGGGCGACGGCGTCTGGGCGCCGTTCTTCG
GCCGCATGGCCTACACCATGACGCTGCCCGGCAAGCTGGCGAGCCAGACCGGCGTGGCCGTCATCCTGAC
CGCCGGCGAACGCCTGCCGGGCGGGCGCGGCTGGCGTATCCACTATGCCCGCGTGCCCGAGCCGCTGCCC
GACGGCCCGCAGGAGCAGGCCGCCCTGATCAACAGCGCCATGGAGTCGCTGATCCGGCGCTTCCCCGAGC
AATACCTGTGGGGATACAACCGCTACAAAGTCCCGCGTGGCGCACCGCCGGCGCCCGACAGCGCGCGGCA
GGAACCCGAACGATG
Protein Sequence 
>gi|33593999|ref|NP_881643.1| lipid A biosynthesis lauroyl acyltransferase [Bordetella pertussis Tohama I]
MLVTLLRMAAALPLPFLHAAGRLLGRLAYAFPGKYRDRLRANAAQAGYPQPAFARRAAGEIGAMILEMPK
VWFRNEQSLGKVVSDDYAIVEAARAEGRGILFLTPHLGCFEITARYLARQMPMTVMFRPPRKAALAPVLE
TARNTSAVNAVPATMQGVRTLRRGESVGMLPDQAPGVGDGVWAPFFGRMAYTMTLPGKLASQTGVAVILT
AGERLPGGRGWRIHYARVPEPLPDGPQEQAALINSAMESLIRRFPEQYLWGYNRYKVPRGAPPAPDSARQ
EPER
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lpxL1 deficient mutant displayed defect in infection of human macrophages (Geurtsen et al., 2007).
COG COG1560M, under M: Cell wall/membrane/envelope biogenesis
References
Geurtsen et al., 2007: Geurtsen J, Angevaare E, Janssen M, Hamstra HJ, ten Hove J, de Haan A, Kuipers B, Tommassen J, van der Ley P. A novel secondary acyl chain in the lipopolysaccharide of Bordetella pertussis required for efficient infection of human macrophages. The Journal of biological chemistry. 2007; 282(52); 37875-37884. [PubMed: 17967899].