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ptxB

Victor ID 3958
Gene Name ptxB
Sequence Strain (Species/Organism) Bordetella pertussis
NCBI Gene ID 2665069
NCBI Protein GI 33594639
Locus Tag BP3784
Protein Accession NP_882283.1
Other Database IDs UniProtKB-ID: TOX2_BORPE
UniRef100: UniRef100_P04978
UniRef90: UniRef90_P04978
UniRef50: UniRef50_P04979
UniParc: UPI00001B77C6
EMBL: M14378
EMBL: M13223
EMBL: BX640422
EMBL-CDS: AAA83981.1
EMBL-CDS: AAA22982.1
EMBL-CDS: CAE44039.1
RefSeq_NT: NC_002929.2
PDB: 1BCP
PDB: 1PRT
PDB: 1PTO
TCDB: 1.C.72.1.1
GenomeReviews: BX470248_GR
KEGG: bpe:BP3784
NMPDR: fig|257313.1.peg.3353
HOGENOM: HBG037688
OMA: HVARAST
ProtClustDB: CLSK270097
BioCyc: BPER257313:BP3784-MONOMER
Taxonomy ID 257313
Gene Starting Position 3989106
Gene Ending Position 3989786
Gene Strand (Orientation) +
Protein Name toxin subunit 2
DNA Sequence 
>gi|33591275:3989106-3989786 Bordetella pertussis Tohama I, complete genome
CATGCCGATCGACCGCAAGACGCTCTGCCATCTCCTGTCCGTTCTGCCGTTGGCCCTCCTCGGATCTCAC
GTGGCGCGGGCCTCCACGCCAGGCATCGTCATTCCGCCGCAGGAACAGATTACCCAGCATGGCGGCCCCT
ATGGACGCTGCGCGAACAAGACCCGTGCCCTGACCGTGGCGGAATTGCGCGGCAGCGGCGATCTGCAGGA
GTACCTGCGTCATGTGACGCGCGGCTGGTCAATATTTGCGCTCTACGATGGCACCTATCTCGGCGGCGAA
TATGGCGGCGTGATCAAGGACGGAACACCCGGCGGCGCATTCGACCTGAAAACGACGTTCTGCATCATGA
CCACGCGCAATACGGGTCAACCCGCAACGGATCACTACTACAGCAACGTCACCGCCACTCGCCTGCTCTC
CAGCACCAACAGCAGGCTATGCGCGGTCTTCGTCAGAAGCGGGCAACCGGTCATTGGCGCCTGCACCAGC
CCGTATGACGGCAAGTACTGGAGCATGTACAGCCGGCTGCGGAAAATGCTTTACCTGATCTACGTGGCCG
GCATCTCCGTACGCGTCCATGTCAGCAAGGAAGAACAGTATTACGACTATGAGGACGCAACGTTCGAGAC
TTACGCCCTTACCGGCATCTCCATCTGCAATCCTGGATCATCCTTATGCTG
Protein Sequence 
>gi|33594639|ref|NP_882283.1| pertussis toxin subunit 2 [Bordetella pertussis Tohama I] MPIDRKTLCHLLSVLPLALLGSHVARASTPGIVIPPQEQITQHGGPYGRCANKTRALTVAELRGSGDLQEYLRHVTRGWSIFALYDGTYLGGEYGGVIKDGTPGGAFDLKTTFCIMTTRNTGQPATDHYYSNVTATRLLSSTNSRLCAVFVRSGQPVIGACTSPYDGKYWSMYSRLRKMLYLIYVAGISVRVHVSKEEQYYDYEDATFETYALTGISICNPGSSLC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion mutant displayed a significant defect in respiratory tract colonization in mice (Carbonetti et al., 2004).
References
Carbonetti et al., 2004: Carbonetti NH, Artamonova GV, Andreasen C, Dudley E, Mays RM, Worthington ZE. Suppression of serum antibody responses by pertussis toxin after respiratory tract colonization by Bordetella pertussis and identification of an immunodominant lipoprotein. Infection and immunity. 2004; 72(6); 3350-3358. [PubMed: 15155640].