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ptxA

Victor ID 3957
Gene Name ptxA
Sequence Strain (Species/Organism) Bordetella pertussis
NCBI Gene ID 2665068
NCBI Protein GI 33594638
Locus Tag BP3783
Protein Accession NP_882282.1
Other Database IDs UniProtKB-ID: TOX1_BORPE
UniRef100: UniRef100_P04977
UniRef90: UniRef90_Q7WDU8
UniRef50: UniRef50_P04977
UniParc: UPI000000030D
EMBL: M14378
EMBL: M13223
EMBL: X16347
EMBL: AJ245366
EMBL: AJ245367
EMBL: AJ245368
EMBL: AJ506996
EMBL: AJ006151
EMBL: AJ006153
EMBL: AJ006155
EMBL: AJ006157
EMBL: AJ006159
EMBL: AJ007363
EMBL: AJ007364
EMBL: AJ506994
EMBL: AJ506995
EMBL: AY879289
EMBL: AJ920066
EMBL: BX640422
EMBL-CDS: AAA83980.1
EMBL-CDS: AAA22981.1
EMBL-CDS: CAA34397.1
EMBL-CDS: CAB51472.1
EMBL-CDS:
Taxonomy ID 257313
Gene Starting Position 3988257
Gene Ending Position 3989066
Gene Strand (Orientation) +
Protein Name toxin subunit 1
DNA Sequence 
>gi|33591275:3988257-3989066 Bordetella pertussis Tohama I, complete genome
GATGCGTTGCACTCGGGCAATTCGCCAAACCGCAAGAACAGGCTGGCTGACGTGGCTGGCGATTCTTGCC
GTCACGGCGCCCGTGACTTCGCCGGCATGGGCCGACGATCCTCCCGCCACCGTATACCGCTATGACTCCC
GCCCGCCGGAGGACGTTTTCCAGAACGGATTCACGGCGTGGGGAAACAACGACAATGTGCTCGACCATCT
GACCGGACGTTCCTGCCAGGTCGGCAGCAGCAACAGCGCTTTCGTCTCCACCAGCAGCAGCCGGCGCTAT
ACCGAGGTCTATCTCGAACATCGCATGCAGGAAGCGGTCGAGGCCGAACGCGCCGGCAGGGGCACCGGCC
ACTTCATCGGCTACATCTACGAAGTCCGCGCCGACAACAATTTCTACGGCGCCGCCAGCTCGTACTTCGA
ATACGTCGACACTTATGGCGACAATGCCGGCCGTATCCTCGCCGGCGCGCTGGCCACCTACCAGAGCGAA
TATCTGGCACACCGGCGCATTCCGCCCGAAAACATCCGCAGGGTAACGCGGGTCTATCACAACGGCATCA
CCGGCGAGACCACGACCACGGAGTATTCCAACGCTCGCTACGTCAGCCAGCAGACTCGCGCCAATCCCAA
CCCCTACACATCGCGAAGGTCCGTAGCGTCGATCGTCGGCACATTGGTGCGCATGGCGCCGGTGATAGGC
GCTTGCATGGCGCGGCAGGCCGAAAGCTCCGAGGCCATGGCAGCCTGGTCCGAACGCGCCGGCGAGGCGA
TGGTTCTCGTGTACTACGAAAGCATCGCGTATTCGTTCTA
Protein Sequence 
>gi|33594638|ref|NP_882282.1| pertussis toxin subunit 1 [Bordetella pertussis Tohama I] MRCTRAIRQTARTGWLTWLAILAVTAPVTSPAWADDPPATVYRYDSRPPEDVFQNGFTAWGNNDNVLDHLTGRSCQVGSSNSAFVSTSSSRRYTEVYLEHRMQEAVEAERAGRGTGHFIGYIYEVRADNNFYGAASSYFEYVDTYGDNAGRILAGALATYQSEYLAHRRIPPENIRRVTRVYHNGITGETTTTEYSNARYVSQQTRANPNPYTSRRSVASIVGTLVRMAPVIGACMARQAESSEAMAAWSERAGEAMVLVYYESIAYSF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion mutant displayed a significant defect in respiratory tract colonization in mice (Carbonetti et al., 2004).
References
Carbonetti et al., 2004: Carbonetti NH, Artamonova GV, Andreasen C, Dudley E, Mays RM, Worthington ZE. Suppression of serum antibody responses by pertussis toxin after respiratory tract colonization by Bordetella pertussis and identification of an immunodominant lipoprotein. Infection and immunity. 2004; 72(6); 3350-3358. [PubMed: 15155640].