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exbB

Victor ID 3956
Gene Name exbB
Sequence Strain (Species/Organism) Bordetella pertussis Tohama I
NCBI Gene ID 2664932
NCBI Protein GI 33594403
Locus Tag BP3532
Genbank Accession BX640421
Protein Accession NP_882047
Other Database IDs UniProtKB-ID: Q9S3M5_BORPE
UniRef100: UniRef100_Q9S3M5
UniRef90: UniRef90_Q7W7I3
UniRef50: UniRef50_A9IQA7
UniParc: UPI00000B0C55
EMBL: AJ132741
EMBL: BX640421
EMBL-CDS: CAB53384.1
EMBL-CDS: CAE43791.1
RefSeq_NT: NC_002929.2
GenomeReviews: BX470248_GR
KEGG: bpe:BP3532
NMPDR: fig|257313.1.peg.3117
HOGENOM: HBG681852
OMA: ENEIVTH
ProtClustDB: CLSK921105
BioCyc: BPER257313:BP3532-MONOMER
Taxonomy ID 257313
Gene Starting Position 3743707
Gene Ending Position 3744684
Gene Strand (Orientation) +
Protein Name MotA/TolQ/ExbB proton channel family protein
Protein pI 7.47
Protein Weight 30877.55
Protein Length 325
Protein Note C-terminal region is similar to Escherichia coli inner membrane protein that maintains integrity of cell envelope and tolerance to group A colicins TolQ SW:TOLQ_ECOLI (P05828) (230 aa) fasta scores: E(): 2.1e-13, 31.87% id in 229 aa. Previously sequenced as Bordetella pertussis putative biopolymer transport protein ExbB TR:Q9S3M5 (EMBL: AJ132741) (325 aa) fasta scores: E(): 1.2e-103, 100% id in 325 aa
DNA Sequence 
>gi|33591275:3743707-3744684 Bordetella pertussis Tohama I, complete genome
GATGTCCAACGCTATCAACACCGCCACGCTGGTGGCGCAAGCGGCCACGCCCTCGGCGGCGGCCACGCCG
GACGCGCCCGCTGCCGCGCCGCTGGCCCAGCAGGCCGGCGAGGCCGCAGGCGCTGCTGCCCAGACCGGCG
CCGAAGCGCTCAACCAGGCTGCCCAGGCAGGTACCGAGGCGGTCAACCAGGCCGCCCAGGCTCTGAGTGC
GGCGGCGCCCGCCGTGCCGCCCGCGCCGCTGGCCACGCCGGACATGGGATTCCTGCACTTCGTCGCGCAA
AGCGACTTCGTGGGCAAGACGCTGTTCATCATCCTGATCGTCATGTCGCTGGTCACCTGGTACCTGATCG
TGGTCAAGGTGGTGGGCAACATGGGTATGCGCAAGCGCGCCGCGCACTTCCTCAACAAGTTCTGGAATGC
CAGCTCGCTCGAACAGGTCGAGAACGAAATCGTCACGCACGGTGCGCGCGACCCGTTCTCGCACCTGGCC
AGCCACGCCATGCACGCGCAGCAGCACCATGCCAAGTTCGGCGCTACCAAGCTGGAGGAAAGCGGTTCGA
ATGGCGAGTTCGTGTCGCGCACCATGCGCAAGGTCATCGACGAGGAAACCGCCAAGCTGGAGAACGGCCT
GACGGTGCTGGCTTCGGTGGGTTCGACCGCGCCGTTCGTGGGGCTGTTCGGCACAGTGTGGGGCGTGTAT
CACGCGCTGGTCGGCATCGGCCTGTCCGATGGCGTGACCATCAACCGCATCGCCGGCCCGGTGGGCGAGG
CCCTGATCATGACCGGCCTGGGCCTGGCGGTGGCCATCCCGGCGGTGCTGGCGTACAACGCCTTCGTGCG
CAACAACCGGGTGTTCCTGTCGCGCCTGGATGCGTTCGCGCATGACCTGTTCGCCTTCCTGACCACCGGC
CAGCAGGTGGCGGTGTCCGACGGCAAGGTGCGTGCCCTGCGCCGCCAGCATGGCCGGGGGAGCGAATA
Protein Sequence 
>gi|33594403|ref|NP_882047.1| MotA/TolQ/ExbB proton channel family protein [Bordetella pertussis Tohama I]
MSNAINTATLVAQAATPSAAATPDAPAAAPLAQQAGEAAGAAAQTGAEALNQAAQAGTEAVNQAAQALSA
AAPAVPPAPLATPDMGFLHFVAQSDFVGKTLFIILIVMSLVTWYLIVVKVVGNMGMRKRAAHFLNKFWNA
SSLEQVENEIVTHGARDPFSHLASHAMHAQQHHAKFGATKLEESGSNGEFVSRTMRKVIDEETAKLENGL
TVLASVGSTAPFVGLFGTVWGVYHALVGIGLSDGVTINRIAGPVGEALIMTGLGLAVAIPAVLAYNAFVR
NNRVFLSRLDAFAHDLFAFLTTGQQVAVSDGKVRALRRQHGRGSE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tonB exbB double mutant is attenuated in mice (Pradel et al., 2000).
COG COG0811U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Pradel et al., 2000: Pradel E, Guiso N, Menozzi FD, Locht C. Bordetella pertussis TonB, a Bvg-independent virulence determinant. Infection and immunity. 2000; 68(4); 1919-1927. [PubMed: 10722583].