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tonB

Victor ID 3955
Gene Name tonB
Sequence Strain (Species/Organism) Bordetella pertussis Tohama I
NCBI Gene ID 2664931
NCBI Protein GI 33594402
Locus Tag BP3531
Genbank Accession BX640421
Protein Accession NP_882046
Other Database IDs UniProtKB-ID: Q9S3M6_BORPE
UniRef100: UniRef100_Q9S3M6
UniRef90: UniRef90_Q7W7I4
UniRef50: UniRef50_A9IQB0
UniParc: UPI00000B4CDA
EMBL: AJ132741
EMBL: BX640421
EMBL-CDS: CAB53383.1
EMBL-CDS: CAE43790.1
RefSeq_NT: NC_002929.2
GenomeReviews: BX470248_GR
KEGG: bpe:BP3531
NMPDR: fig|257313.1.peg.3116
HOGENOM: HBG353642
OMA: MIMTSIT
ProtClustDB: CLSK921104
BioCyc: BPER257313:BP3531-MONOMER
Taxonomy ID 257313
Gene Starting Position 3742905
Gene Ending Position 3743705
Gene Strand (Orientation) +
Protein Name siderophore-mediated iron transport protein
Protein pI 5.11
Protein Weight 26349.29
Protein Length 266
Protein Note Previously sequenced as Bordetella pertussis siderophore-mediated iron transport protein TonB TR:Q9S3M6 (EMBL: AJ132741) (266 aa) fasta scores: E(): 2.2e-64, 100% id in 266 aa. Similar to Pseudomonas aeruginosa siderophore-mediated iron transport protein TonB SW:TONB_PSEAE (Q51368) (342 aa) fasta scores: E(): 8.2e-11, 34.9% id in 255 aa. Contains a proline rich region, residues 74 to 150
DNA Sequence 
>gi|33591275:3742905-3743705 Bordetella pertussis Tohama I, complete genome
CATGCCTAGCCCCCAATCTGGTCGGTCTTTTTCATCGCATACGTCGCTTGCCCTGCGCGCGGGCGCCGGA
TTTACCGTTCTTGCCCTGCATGCCGCAGTCATAGGCGCGGTGTTTCTGTCCAAGACGGAGCGCCCCGAAT
TGCTGGAGCCCGAGGCGGTGATGGTCAGCATCATCGAGGCGCCCCTGCCGCAGCTGGCGCAGGCCGAGCC
CACGCCCGAGCCGCCCACGCCGGTCGAGGAGACGCCGCCCGAGCCCGAGCCGGTGATCGAGCCCGAGCCG
GAGCCGGAACCCGAGCCGGTGGTCGAGCCCGAGCCCGAACCCGAGCCGGTGGTCGAGAAGCCGCCCGAAC
CGGCGCCCAAGCCCAAGCCGAAACCCAAACCGAAACCCAAGCCCAAGCCGCAACCCAAACCCGAGGTCCC
CCCGGAGCCCAAGAAGATCGAGACGCCGCCTGCCGGCGCGCCTCAGGGGGCCCAGCAGGTGACGCAGGCG
CCGCGCCAGGCGCCGCCGCCGGACGAGCCCATCATGGTCTCCAGCGTCGAATACCAGGGCGCGCGCCCCA
TGCCCGTCTATCCCATGGCGTCCAAGCGCCTGCGCGAGGAAGGGCGGGTGGTGGTGCTGGTGGAAATCAG
CACCCAGGGCCTGGTCGATCGCGCCAGCATCGATACCTCGTCCGGCTTTTCGCGCCTGGACGAGTCGGCC
TTGGCCGCCGCGCGCAAGGCCCGCTTCAAACCCCTTACCCGTAATGGCGTGGCGTATCCGGCCAAGGCCA
AATTACCGTTCGATTTCGTGATGAGGAACTG
Protein Sequence 
>gi|33594402|ref|NP_882046.1| siderophore-mediated iron transport protein [Bordetella pertussis Tohama I]
MPSPQSGRSFSSHTSLALRAGAGFTVLALHAAVIGAVFLSKTERPELLEPEAVMVSIIEAPLPQLAQAEP
TPEPPTPVEETPPEPEPVIEPEPEPEPEPVVEPEPEPEPVVEKPPEPAPKPKPKPKPKPKPKPQPKPEVP
PEPKKIETPPAGAPQGAQQVTQAPRQAPPPDEPIMVSSVEYQGARPMPVYPMASKRLREEGRVVVLVEIS
TQGLVDRASIDTSSGFSRLDESALAAARKARFKPLTRNGVAYPAKAKLPFDFVMRN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tonB exb double mutant is attenuated in mice (Pradel et al., 2000).
COG COG0810M, under M: Cell wall/membrane/envelope biogenesis
References
Pradel et al., 2000: Pradel E, Guiso N, Menozzi FD, Locht C. Bordetella pertussis TonB, a Bvg-independent virulence determinant. Infection and immunity. 2000; 68(4); 1919-1927. [PubMed: 10722583].