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brkB

Victor ID 3953
Gene Name brkB
Sequence Strain (Species/Organism) Bordetella pertussis Tohama I
NCBI Gene ID 2664891
NCBI Protein GI 33594368
Locus Tag BP3493
Genbank Accession BX640421
Protein Accession NP_882012
Other Database IDs UniProtKB-ID: Q45339_BORPE
UniRef100: UniRef100_Q45339
UniRef90: UniRef90_Q45339
UniRef50: UniRef50_Q0JY20
UniParc: UPI00000AF086
EMBL: U12276
EMBL: BX640421
EMBL-CDS: AAA51647.1
EMBL-CDS: CAE43754.1
RefSeq_NT: NC_002929.2
GenomeReviews: BX470248_GR
KEGG: bpe:BP3493
HOGENOM: HBG701087
OMA: NYSSLIL
ProtClustDB: CLSK921095
BioCyc: BPER257313:BP3493-MONOMER
Taxonomy ID 257313
Gene Starting Position 3701864
Gene Ending Position 3702754
Gene Strand (Orientation) -
Protein Name serum resistance protein
Protein pI 9.91
Protein Weight 29835.6
Protein Length 296
Protein Note Similar to Bordetella pertussis serum resistance protein BrkB TR:Q45339 (EMBL: U12276) (296 aa) fasta scores: E(): 3.8e-111, 100% id in 296 aa. Similar to the N-terminal region of Rhizobium loti hypothetical protein MLL2378 TR:Q98IJ2 (EMBL: AP002999) (339 aa) fasta scores: E(): 3.1e-35, 39.28% id in 280 aa
DNA Sequence 
>gi|33591275:3701864-3702754 Bordetella pertussis Tohama I, complete genome
TTCAGGCGGGGGCGGCCCGGCGCAGGCTGCCGAAGCGCTCGGCGAACTGCCGGGTGAAGACGGCGCCGAA
GAAGAAAATCTGCGCTGAATAATAGATCCACAGCAGCAGCGCGATCAGCGAACCCGCCGCCCCGTACGCC
GATACCGCCGCGCCGCGTCCCAGGTACAGGCCGATGCCCCATTTGCCGGCCAGGAACAGCGCCGCGGTCA
CGATCGCGCCGGGTATCACGTCGAGCCAGGGAATGCGCTTGCTGGGCAGCAGCTTGTAGACCACGGCGAA
CAGCGCGGTCACCACCGCGAACGAAAAGAGGTTCGACAGCCAGTCGGCCGCCATCGCGAAGGCCGATGTG
CTCCATAGATCGCCGTAGTATCCCTTGGCCGCGCCCAGCGCCGCGTTGAGGGTCAGCGAAAGCAGCAGGA
ACAGCGCCAGCACCAGCACCAGGCCGAATGACAGCATGCGGCTGCGCACCAGCCCCTGCAAACCGCTCTT
GTCTTCCTTGACGTCCCACAGTTCGTCCAGGCTGGCCTTGAGTTCGGCGAAGGCCGTGGTGGCGCTGAAC
ACCAGCACGCATATCGACAGCAGCGCGGCCAGCCAGCCGCTGCCCGATTCGTGCGCGCTGGCCAGCACCG
TCTGGATCACCTCGGCGCCGCGCTCGCCGGTGAGGTCGCGCACCTGGCTGAACAGTTCCGAGCGCACGGC
CTCTTCGCCAAAGAAGGCGCCGGCCACCGCGATCACCAGGATCAGCATGGGCGCCAGCGAGAACACCATG
TACAGCGACAGCGCCGCCCCCTTGCTGGAAGCGCGATGGCGCGACCATTCGCGGGCCGAATCGGTCAGCA
GCGCGCCGATGTCGCGGAGGTGGGGCAAGCGGATCTGGCGTGGCAAGCGCA
Protein Sequence 
>gi|33594368|ref|NP_882012.1| serum resistance protein [Bordetella pertussis Tohama I]
MRLPRQIRLPHLRDIGALLTDSAREWSRHRASSKGAALSLYMVFSLAPMLILVIAVAGAFFGEEAVRSEL
FSQVRDLTGERGAEVIQTVLASAHESGSGWLAALLSICVLVFSATTAFAELKASLDELWDVKEDKSGLQG
LVRSRMLSFGLVLVLALFLLLSLTLNAALGAAKGYYGDLWSTSAFAMAADWLSNLFSFAVVTALFAVVYK
LLPSKRIPWLDVIPGAIVTAALFLAGKWGIGLYLGRGAAVSAYGAAGSLIALLLWIYYSAQIFFFGAVFT
RQFAERFGSLRRAAPA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in infant mice (Smith et al., 2001).
COG COG1295S, under S: Function unknown
References
Smith et al., 2001: Smith AM, Guzmán CA, Walker MJ. The virulence factors of Bordetella pertussis: a matter of control. FEMS microbiology reviews. 2001; 25(3); 309-333. [PubMed: 11348687].