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clpP from Streptococcus pneumoniae JJA

Victor ID 3936
Gene Name clpP from Streptococcus pneumoniae JJA
Sequence Strain (Species/Organism) Streptococcus pneumoniae JJA
NCBI Gene ID 7680127
NCBI Protein GI 225854255
Locus Tag SPJ_0685
Protein Accession YP_002735767.1
Other Database IDs UniProtKB-ID: CLPP_STRZJ
UniRef100: UniRef100_Q04LF4
UniRef90: UniRef90_Q1JDA9
UniRef50: UniRef50_Q8YQX8
UniParc: UPI000005157D
EMBL: CP000919
EMBL-CDS: ACO18891.1
RefSeq_NT: NC_012466.1
EnsemblGenome: EBSTRG00000077242
EnsemblGenome_TRS: EBSTRT00000076081
EnsemblGenome_PRO: EBSTRP00000072090
GenomeReviews: CP000919_GR
KEGG: sjj:SPJ_0685
OMA: SPMEAQD
ProtClustDB: PRK00277
BioCyc: SPNE1313:SPJ_0685-MONOMER
Taxonomy ID 488222
Gene Starting Position 661780
Gene Ending Position 662370
Gene Strand (Orientation) +
Protein Name Clp protease
DNA Sequence 
>gi|225853611:661780-662370 Streptococcus pneumoniae JJA, complete genome
AATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTC
AAAGACCGCATCATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGC
TTTTCTTGGATGCCCAAGATAGTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTC
AGCTGGTTTGGCAATCGTAGATACCATGAACTTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATG
GCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAAAGGCAAACGTTTCATGCTTCCAAATGCTG
AATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAACTGATATGGCTATCGCTGC
AGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAGTCAATGGAA
AAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTG
ATGAAATTATGGCCAACAATTCATTGAACTA
Protein Sequence 
>gi|225854255|ref|YP_002735767.1| ATP-dependent Clp protease proteolytic subunit [Streptococcus pneumoniae JJA] MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQSMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: clpP mutant is attenuated in mice (Ibrahim et al., 2005).
COG COG0740OU, under O: Posttranslational modification, protein turnover, chaperones; U: Intracellular trafficking, secretion, and vesicular transport
References
Ibrahim et al., 2005: Ibrahim YM, Kerr AR, Silva NA, Mitchell TJ. Contribution of the ATP-dependent protease ClpCP to the autolysis and virulence of Streptococcus pneumoniae. Infection and immunity. 2005; 73(2); 730-740. [PubMed: 15664911].