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luxS from Streptococcus pneumoniae JJA

Victor ID 3931
Gene Name luxS from Streptococcus pneumoniae JJA
Sequence Strain (Species/Organism) Streptococcus pneumoniae JJA
NCBI Gene ID 7678909
NCBI Protein GI 225853922
Locus Tag SPJ_0332
Protein Accession YP_002735434.1
Other Database IDs UniProtKB-ID: LUXS_STRZJ
UniRef100: UniRef100_B8ZL57
UniRef90: UniRef90_Q04MC2
UniRef50: UniRef50_Q1JAI5
UniParc: UPI000172AFBC
EMBL: CP000919
EMBL-CDS: ACO18800.1
RefSeq_NT: NC_012466.1
EnsemblGenome: EBSTRG00000075993
EnsemblGenome_TRS: EBSTRT00000075762
EnsemblGenome_PRO: EBSTRP00000070519
GenomeReviews: CP000919_GR
KEGG: sjj:SPJ_0332
OMA: VRIAKTM
ProtClustDB: PRK02260
BioCyc: SPNE1313:SPJ_0332-MONOMER
Taxonomy ID 488222
Gene Starting Position 307886
Gene Ending Position 308368
Gene Strand (Orientation) -
Protein Name S-ribosylhomocysteinase LuxS
DNA Sequence 
>gi|225853611:307886-308368 Streptococcus pneumoniae JJA, complete genome
TTTAAATCACATGACGTTCAAAGGCATCATCTGAAATCCCTTGTTCCAAGATGAGTCTTGCCCATTCTTT
AGCAGAGAAGAGGCTGTGGTCCTTGTAGTTTCCGCAAGATTCGATGGTTGTCCCTGGGACATCTTCCCAA
GTAGTAGTTTCAGCGATTTCCTTGAGCGAATCCTTGATAACAGCTGCGATTTTAGCACTGGTGTGACGTC
CCCACATAATCATGTGGAAGCCTGTGCGACAACCAAATGGTGAACAGTCAATCATGCCGTCAATGCGGGT
ACGGATGAGTTTGGCTAAGAGGTGCTCGATAGTGTGAAGGCCGGCAGTAGGGATAGAGTCTTCGTTTGGT
TGCACCAAGCGAATATCATAATTGGAGATGATGTCTCCTTTTGGTCCTGTTTCTTCCCCAATCAAGCGAA
CATAGGGTGCTTTGACAATGGTGTGGTCAAGTTCAAAACTTTCGACAATAACTTCTTTTGACA
Protein Sequence 
>gi|225853922|ref|YP_002735434.1| S-ribosylhomocysteinase [Streptococcus pneumoniae JJA] MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWARLILEQGISDDAFERHVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: luxS mutant has defective ability to persist in the nasopharyngeal tissues of mice (Joyce et al., 2004).
COG COG1854T, under T: Signal transduction mechanisms
References
Joyce et al., 2004: Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S. LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Infection and immunity. 2004; 72(5); 2964-2975. [PubMed: 15102809].