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glnA from Streptococcus pneumoniae P1031

Victor ID 3929
Gene Name glnA from Streptococcus pneumoniae P1031
Sequence Strain (Species/Organism) Streptococcus pneumoniae P1031
NCBI Gene ID 7682623
NCBI Protein GI 225856221
Locus Tag SPP_0524
Protein Accession YP_002737732.1
Other Database IDs UniProtKB-ID: C1CIZ4_STRZP
UniRef100: UniRef100_E0SWB5
UniRef90: UniRef90_E0TSP1
UniRef50: UniRef50_D5T5L0
UniParc: UPI000152E1BD
EMBL: CP000920
EMBL-CDS: ACO21126.1
RefSeq_NT: NC_012467.1
EnsemblGenome: EBSTRG00000080171.
EnsemblGenome_TRS: EBSTRT00000081851
EnsemblGenome_PRO: EBSTRP00000075254
GenomeReviews: CP000920_GR
KEGG: spp:SPP_0524
OMA: RVPLYKP
ProtClustDB: CLSK876973
BioCyc: SPNE1313-1:SPP_0524-MONOMER
Taxonomy ID 488223
Gene Starting Position 474717
Gene Ending Position 476063
Gene Strand (Orientation) +
Protein Name glutamine synthetase, type I
DNA Sequence 
>gi|225855735:474717-476063 Streptococcus pneumoniae P1031, complete genome
TATGCCAATCACAGCTGCAGATATTCGTCGTGAAGTCAAGGAAAAAAATGTTACCTTTATTCGTCTTATG
TTCTCAGATATTTTGGGAACCATGAAAAACGTCGAAATTCCTGCTACAGATGAACAGTTAGATAAGGTCT
TGTCGAACAAGGTTATGTTTGATGGATCTTCTATTGAAGGTTTTGTACGTATCAATGAGTCGGATATGTA
CTTGTACCCGGACTTGGATACATGGACAGTCTTCCCTTGGGGAGATGAAAATGGAAGTGTTGCAGGTCTG
ATCTGTGATGTCTATACAACAGAAGGTGAACCATTTGCGGGTGACCCTCGTGGTAATTTGAAACGAGCTC
TTCGTCACATGGAAGAAGTTGGATTCAAATCCTTCAACCTTGGTCCAGAGCCAGAATTCTTCCTATTTAA
GTTGGATGAAAATGGGGACCCAACACTTGAAGTGAATGACAAGGGTGGCTACTTTGATTTGGCACCTACT
GACCTTGCGGACAACACACGTCGTGAGATTGTGAATGTCTTGACCAAAATGGGATTTGAAGTAGAAGCGA
GTCACCACGAGGTTGCGGTTGGACAGCATGAGATTGACTTTAAGTACGATGAAGTTCTCCGTGCTTGTGA
TAAGATTCAAATCTTTAAACTTGTTGTTAAAACCATTGCTCGCAAACACGGACTTTACGCAACATTTATG
GCGAAGCCAAAATTTGGTATTGCTGGCTCAGGTATGCACTGTAATATGTCCTTGTTTGATGCAGAAGGAA
ATAACGCCTTCTTTGATCCAAATGATCCAAAAGGAATGCAGTTGTCAGAAACAGCTTACCATTTCCTAGG
CGGTTTGATCAAGCATGCTTACAACTATACTGCCATCATGAACCCAACAGTTAACTCATACAAACGTTTG
GTTCCAGGTTATGAAGCGCCTGTTTACATTGCTTGGGCTGGTCGTAACCGTTCGCCACTTGTGCGCGTAC
CTGCTTCACGTGGTATGGGAACTCGTCTTGAGTTGCGTTCAGTGGATCCAATGGCGAACCCTTACATTGC
TATGGCTGTTCTTTTGGAAGTTGGTTTGTATGGTATTGAAAATAAAATCGAAGCACCAGCTCCTATCGAA
GAAAATATCTACATCATGACAGCAGAAGAGCGCAAGGAAGCTGGTATTACAGACCTTCCATCAACTCTTC
ATAATGCTTTGAAAGCTTTGACAGAAGATGAAGTGGTTAAAGCTGCTCTCGGAGATCACATCTACACTAG
CTTCCTTGAAGCCAAACGAATCGAATGGGCAAGTTATGCAACCTTCGTTTCACAATGGGAAATTGATAAT
TATTTAGACCTTTACTA
Protein Sequence 
>gi|225856221|ref|YP_002737732.1| glutamine synthetase, type I [Streptococcus pneumoniae P1031] MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLDKVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEGEPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDLAPTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLVVKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAYHFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGTRLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDLPSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: glnA mutant had significantly reduced adhesion to Detroit 562 human pharyngeal epithelial cells (Kloosterman et al., 2006).
COG COG0174E, under E: Amino acid transport and metabolism
References
Kloosterman et al., 2006: Kloosterman TG, Hendriksen WT, Bijlsma JJ, Bootsma HJ, van Hijum SA, Kok J, Hermans PW, Kuipers OP. Regulation of glutamine and glutamate metabolism by GlnR and GlnA in Streptococcus pneumoniae. The Journal of biological chemistry. 2006; 281(35); 25097-25109. [PubMed: 16787930].