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luxS from Streptococcus pneumoniae P1031

Victor ID 3925
Gene Name luxS from Streptococcus pneumoniae P1031
Sequence Strain (Species/Organism) Streptococcus pneumoniae P1031
NCBI Gene ID 7680711
NCBI Protein GI 225856082
Locus Tag SPP_0375
Protein Accession YP_002737593.1
Other Database IDs UniProtKB-ID: LUXS_STRZP
UniRef100: UniRef100_Q04MC2
UniRef90: UniRef90_Q04MC2
UniRef50: UniRef50_Q1JAI5
UniParc: UPI00000513CE
EMBL: CP000920
EMBL-CDS: ACO20637.1
RefSeq_NT: NC_012467.1
EnsemblGenome: EBSTRG00000079792
EnsemblGenome_TRS: EBSTRT00000080087
EnsemblGenome_PRO: EBSTRP00000076135
GenomeReviews: CP000920_GR
KEGG: spp:SPP_0375
OMA: VRIAKTM
ProtClustDB: PRK02260
BioCyc: SPNE1313-1:SPP_0375-MONOMER
Taxonomy ID 488223
Gene Starting Position 328922
Gene Ending Position 329404
Gene Strand (Orientation) -
Protein Name S-ribosylhomocysteinase LuxS
DNA Sequence 
>gi|225855735:328922-329404 Streptococcus pneumoniae P1031, complete genome
TTTAAATCACATGACGTTCAAAGGCATCATCTGAAATCCCTTGTTCCAAGATGAGTTTTGCCCATTCTTT
AGCAGAGAAGAGGCTGTGGTCCTTGTAGTTTCCGCAAGATTCGATGGTTGTCCCTGGGACATCTTCCCAA
GTAGTAGTTTCAGCGATTTCCTTGAGCGAATCCTTGATAACAGCTGCGATTTTAGCACTGGTGTGACGTC
CCCACATAATCATGTGGAAGCCTGTGCGGCAACCAAATGGTGAACAGTCAATCATGCCGTCAATGCGGGT
ACGGATGAGTTTGGCTAAGAGGTGCTCGATAGTGTGAAGGCCGGCAGTAGGGATAGAGTCTTCGTTTGGT
TGCACCAAGCGAATATCATAATTGGAGATGATGTCTCCTTTTGGTCCTGTTTCTTCCCCAATCAAGCGAA
CATAGGGTGCTTTGACAATGGTGTGGTCAAGTTCAAAACTTTCGACAATAACTTCTTTTGACA
Protein Sequence 
>gi|225856082|ref|YP_002737593.1| S-ribosylhomocysteinase [Streptococcus pneumoniae P1031] MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: luxS mutant has defective ability to persist in the nasopharyngeal tissues of mice (Joyce et al., 2004).
COG COG1854T, under T: Signal transduction mechanisms
References
Joyce et al., 2004: Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S. LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Infection and immunity. 2004; 72(5); 2964-2975. [PubMed: 15102809].