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glnA from Streptococcus pneumoniae 70585

Victor ID 3922
Gene Name glnA from Streptococcus pneumoniae 70585
Sequence Strain (Species/Organism) Streptococcus pneumoniae 70585
NCBI Gene ID 7684741
NCBI Protein GI 225858342
Locus Tag SP70585_0562
Protein Accession YP_002739852.1
Other Database IDs UniProtKB-ID: C1C5M6_STRP7
UniRef100: UniRef100_C1C5M6
UniRef90: UniRef90_E0TSP1
UniRef50: UniRef50_D5T5L0
UniParc: UPI000198B46F
EMBL: CP000918
EMBL-CDS: ACO17384.1
RefSeq_NT: NC_012468.1
EnsemblGenome: EBSTRG00000073842.
EnsemblGenome_TRS: EBSTRT00000074722
EnsemblGenome_PRO: EBSTRP00000068747
GenomeReviews: CP000918_GR
KEGG: snm:SP70585_0562
ProtClustDB: CLSK876973
BioCyc: SPNE488221:SP70585_0562-MONOMER
Taxonomy ID 488221
Gene Starting Position 511798
Gene Ending Position 513144
Gene Strand (Orientation) +
Protein Name glutamine synthetase, type I
DNA Sequence 
>gi|225857809:511798-513144 Streptococcus pneumoniae 70585, complete genome
TATGCCAATCACAGCTGCAGATATTCGTCGTGAAGTCAATGAAAAAAATGTTACCTTTATTCGTCTTATG
TTCTCAGATATTTTGGGAACCATGAAAAACGTCGAAATTCCTGCTACAGATGAACAGTTAGATAAGGTCT
TGTCGAACAAGGTTATGTTTGATGGATCTTCTATTGAAGGTTTTGTACGTATCAATGAGTCGGATATGTA
CTTGTACCCGGACTTGGATACATGGACAGTCTTCCCTTGGGGAGATGAAAATGGAAGTGTTGCAGGTCTG
ATCTGTGATGTTTATACAACAGAAGGTGAACCATTTGCGGGTGACCCTCGTGGTAATTTGAAACGAGCTC
TTCGTCACATGGAAGAAGTTGGATTCAAATCCTTCAACCTTGGTCCAGAGCCAGAATTCTTCCTATTTAA
GTTGGATGAAAATGGGGACCCAACACTTGAAGTGAATGACAAGGGTGGCTACTTTGATTTGGCACCTACT
GACCTTGCGGACAACACACGTCGTGAGATTGTGAATGTCTTGACCAAAATGGGATTTGAAGTAGAAGCGA
GTCACCACGAGGTTGCGGTTGGACAGCATGAGATTGACTTTAAGTACGATGAAGTTCTCCGTGCTTGTGA
TAAGATTCAAATCTTTAAACTTGTTGTTAAAACCATTGCTCGCAAACACGGACTTTACGCAACATTTATG
GCGAAGCCAAAATTTGGTATTGCTGGCTCAGGTATGCACTGTAATATGTCCTTGTTTGATGCAGAAGGAA
ATAACGCCTTCTTTGATCCAAATGATCCAAAAGGAATGCAGCTGTCAGAAACAGCTTACCATTTCCTAGG
CGGTTTGATCAAGCATGCTTACAACTATACTGCCATCATGAATCCAACAGTTAACTCATACAAACGTTTG
GTTCCAGGTTATGAAGCGCCTGTTTACATTGCTTGGGCTGGTCGTAACCGTTCGCCACTTGTGCGCGTAC
CTGCTTCACGTGGTATGGGAACTCGTCTTGAGTTGCGTTCAGTGGATCCAATGGCGAACCCTTACATTGC
TATGGCTGTTCTTTTAGAAGTTGGTTTGTATGGTATTGAAAATAAAATCGAAGCACCAGCTCCTATCGAA
GAAAATATCTACATCATGACAGCAGAAGAGCGCAAGGAAGCTGGTATTACAGACCTTCCATCAACTCTTC
ACAACGCTTTGAAAGCTTTGACAGAAGATGAAGTGGTTAAAGCTGCTCTCGGAGATCACATCTACACTAG
CTTCCTTGAAGCCAAACGAATCGAATGGGCAAGTTATGCAACCTTCGTTTCACAATGGGAAATTGATAAT
TATTTAGACCTTTACTA
Protein Sequence 
>gi|225858342|ref|YP_002739852.1| glutamine synthetase, type I [Streptococcus pneumoniae 70585] MPITAADIRREVNEKNVTFIRLMFSDILGTMKNVEIPATDEQLDKVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEGEPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDLAPTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLVVKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAYHFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGTRLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDLPSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: glnA mutant had significantly reduced adhesion to Detroit 562 human pharyngeal epithelial cells (Kloosterman et al., 2006).
COG COG0174E, under E: Amino acid transport and metabolism
References
Kloosterman et al., 2006: Kloosterman TG, Hendriksen WT, Bijlsma JJ, Bootsma HJ, van Hijum SA, Kok J, Hermans PW, Kuipers OP. Regulation of glutamine and glutamate metabolism by GlnR and GlnA in Streptococcus pneumoniae. The Journal of biological chemistry. 2006; 281(35); 25097-25109. [PubMed: 16787930].