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luxS from Streptococcus pneumoniae 70585

Victor ID 3921
Gene Name luxS from Streptococcus pneumoniae 70585
Sequence Strain (Species/Organism) Streptococcus pneumoniae 70585
NCBI Gene ID 7684294
NCBI Protein GI 225858194
Locus Tag SP70585_0404
Protein Accession YP_002739704.1
Other Database IDs UniProtKB-ID: LUXS_STRP7
UniRef100: UniRef100_Q04MC2
UniRef90: UniRef90_Q04MC2
UniRef50: UniRef50_Q1JAI5
UniParc: UPI00000513CE
EMBL: CP000918
EMBL-CDS: ACO16011.1
RefSeq_NT: NC_012468.1
EnsemblGenome: EBSTRG00000074916
EnsemblGenome_TRS: EBSTRT00000072904
EnsemblGenome_PRO: EBSTRP00000069880
GenomeReviews: CP000918_GR
KEGG: snm:SP70585_0404
ProtClustDB: PRK02260
BioCyc: SPNE488221:SP70585_0404-MONOMER
Taxonomy ID 488221
Gene Starting Position 357811
Gene Ending Position 358293
Gene Strand (Orientation) -
Protein Name S-ribosylhomocysteinase LuxS
DNA Sequence 
>gi|225857809:357811-358293 Streptococcus pneumoniae 70585, complete genome
TTTAAATCACATGACGTTCAAAGGCATCATCTGAAATCCCTTGTTCCAAGATGAGTTTTGCCCATTCTTT
AGCAGAGAAGAGGCTGTGGTCCTTGTAGTTTCCGCAAGATTCGATGGTTGTCCCTGGGACATCTTCCCAA
GTAGTAGTTTCAGCGATTTCCTTGAGCGAATCCTTGATAACAGCTGCGATTTTAGCACTGGTGTGACGTC
CCCACATAATCATGTGGAAGCCTGTGCGGCAACCAAATGGTGAACAGTCAATCATGCCGTCAATGCGGGT
ACGGATGAGTTTGGCTAAGAGGTGCTCGATAGTGTGAAGACCGGCAGTAGGGATAGAGTCTTCGTTTGGT
TGCACCAAGCGAATATCATAATTGGAGATGATGTCTCCTTTTGGTCCTGTTTCTTCCCCAATCAAGCGAA
CATAGGGTGCTTTGACAATGGTGTGGTCAAGTTCAAAACTTTCGACAATAACTTCTTTTGACA
Protein Sequence 
>gi|225858194|ref|YP_002739704.1| S-ribosylhomocysteinase [Streptococcus pneumoniae 70585] MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: luxS mutant has defective ability to persist in the nasopharyngeal tissues of mice (Joyce et al., 2004).
COG COG1854T, under T: Signal transduction mechanisms
References
Joyce et al., 2004: Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S. LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Infection and immunity. 2004; 72(5); 2964-2975. [PubMed: 15102809].