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codY from Streptococcus pneumoniae 70585

Victor ID 3920
Gene Name codY from Streptococcus pneumoniae 70585
Sequence Strain (Species/Organism) Streptococcus pneumoniae 70585
NCBI Gene ID 7683683
NCBI Protein GI 225859339
Locus Tag SP70585_1624
Protein Accession YP_002740849.1
Other Database IDs UniProtKB-ID: CODY_STRP7
UniRef100: UniRef100_C1C8H3
UniRef90: UniRef90_Q04JG7
UniRef50: UniRef50_A2RCV3
UniParc: UPI000152B52E
EMBL: CP000918
EMBL-CDS: ACO17957.1
RefSeq_NT: NC_012468.1
EnsemblGenome: EBSTRG00000074263
EnsemblGenome_TRS: EBSTRT00000075132
EnsemblGenome_PRO: EBSTRP00000069807
GenomeReviews: CP000918_GR
KEGG: snm:SP70585_1624
ProtClustDB: PRK04158
BioCyc: SPNE488221:SP70585_1624-MONOMER
Taxonomy ID 488221
Gene Starting Position 1501909
Gene Ending Position 1502697
Gene Strand (Orientation) -
Protein Name GTP-sensing transcriptional pleiotropic repressor CodY
DNA Sequence 
>gi|225857809:1501909-1502697 Streptococcus pneumoniae 70585, complete genome
ATTAGTAATCTCTTTTCTTCACTTCTTCAAAAATATCTGAAATCAAGACCTTAAGATAGGTTCCCTTCAT
TCCAAGTGAGCGACTTTCAATAATCCCCGCAGACTCAAGTTTACGAAGAGCATTGACAATCACAGAGCGA
GTGATTCCGATACGATCTGCAATCACTGACGCAGTCAACTTCCCTTCATTTCCATTTAATTCCCCTAAAA
TTGCTGAAACAGCACGGAGTTCGGAGTAAGAAAGGGTATTGACCGCCATGGTGACAGCAGTACGACGACG
AATATTTTTCTCATCTTCTTCACGTTGGAAGTTAAGAAGCTGAATCCCAACAACGGTACTGGCAATCTCA
ACAAGAACCAAGTCCTCATCTTCGAATTTTTTATCATTACGCCAAATAATCAAAGAACCAAGGCGAATCC
CCGATACATGAATCGGTGCAATAGTCGTCAAGCCATCTGGAAAATCATCTCTACTCTCAACAGGGAAAAT
ACTCATATCATGCTCAACAGGCAAGTTTGCTTCTGTTTCGTAAATCATATTAGCCCCTTGAACGTAGTCA
TCTGGGAAAATCTTAGTTTGGAAGAATTGCTCTACGCGATCTGTATTTGTTTTATAACGCATAAAATAGC
CAAGCAGACGTCCCTTACTATTGATAATGCAGGCATTGCAATGAATAATATCCGCTAACTGACGCGTAAT
AGCGTTGTAAGGGAGCTCATCCTGCAACTGCTCCTCTGAGCGTTTCAAAATTGATGTAATTTTTCTAGTT
TTTTCTAATAAATGTGCCA
Protein Sequence 
>gi|225859339|ref|YP_002740849.1| transcriptional repressor CodY [Streptococcus pneumoniae 70585] MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLNFQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: codY mutant has lower bacterial loads during infection in mice compared to the wild type and have a diminished ability to adhere to nasopharangeal cells in vitro (Hendriksen et al., 2008).
COG COG4465K, under K: Transcription
References
Hendriksen et al., 2008: Hendriksen WT, Bootsma HJ, Estevão S, Hoogenboezem T, de Jong A, de Groot R, Kuipers OP, Hermans PW. CodY of Streptococcus pneumoniae: link between nutritional gene regulation and colonization. Journal of bacteriology. 2008; 190(2); 590-601. [PubMed: 18024519].