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HP0397

Victor ID 392
Gene Name HP0397
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 900244
NCBI Protein GI 15645025
Locus Tag HP0397
Protein Accession NP_207195.1
Other Database IDs UniProtKB-ID: O25158_HELPY
UniRef100: UniRef100_O25158
UniRef90: UniRef90_B2UUG3
UniRef50: UniRef50_A6Q7Q2
UniParc: UPI00000D3175
EMBL: AE000511
EMBL-CDS: AAD07461.1
RefSeq_NT: NC_000915.1
HSSP: P08328
DIP: DIP-3725N
MINT: MINT-159526
GenomeReviews: AE000511_GR
KEGG: hpy:HP0397
NMPDR: fig|85962.1.peg.393
TIGR: HP_0397
HOGENOM: HBG731446
OMA: IASMQVG
ProtClustDB: PRK13581
Taxonomy ID 85962
Gene Starting Position 407263
Gene Ending Position 408837
Gene Strand (Orientation) -
Protein Name phosphoglycerate dehydrogenase (serA)
DNA Sequence 
>gi|15644634:407263-408837 Helicobacter pylori 26695, complete genome
CTTAAATAACCACATAATGAACGCTTAAGCACGCAGGAATGTTTTTAAGCTCTTCTAAAACTTCCAAAGA
AACTTCTTCATCTACAATAATGAGTGCTAGGGCTTCTTTTTGCGTGTTACGCCCCAAACGAAAATCAGCG
ATGTTAATGCCATGCCTAGCGAACGCATTCCCCACACTCCCAATAACGCCTGGAATATCCGTATTCCTGA
ATAAAAGCATTTTACCCTTTGGCTCTATATCAATATGAAACCCATCAATCTCAGTGAGTTTTAAAATATC
TTCTTCAAACACCGTGCCGCTCACGCTGATTGTGCCATTAGCCGCATTGAGGGTTAAAGAGAGCATGTTC
TTATAGGGCGAAGCGCTTTCTTTAAGGCTAACCTTAATCTCAATACCTCTTTCTTTGGCCACAAAGGGGG
CGTTAATGTAATTGATTTTATCCCCTACAACAGGTTTTAACACCCCCACTAACATAAAGGCTACAAGAGC
GTCTTTAAATTGGTTGATCTCCCCACAAAGACTGAGCTCAATTTTTTGGCACACGCCCTTATGGATTTGA
CTGGAAAAATAACCCAATTTTTGCGCTAAATTCAAGTAGGCTTTTGCGCTCGCGTCAAAAGCTTGCATGG
GTAAATTCAAAGCATGCGGGTGGCTTGAACCCCTTAAAGATTCCATAACCCCTTGAGCGGCTTGTTTGGA
AATTTCTTCTTGGGATTCTAAAGTGTTTGCGCCAATATGGGGGGTCGCATAAACATTGGGCAAGTCTAAA
AGCTTGTTGTGAATGCCAGGCTCTTTAGAAAAGACATCAATGCCAAGCCAACGCACTTTTTTGGTTTCTA
AAGCCTCATAAAGAGCGTCTTCATTATAAAGCCCACCCCTAGCGCAATTGAGCAAAATAACCCCTTTTTT
CATGCGCTCAATCTCTTTAGCACCTATCATGTTAATCGTTTCTTTATTTTTAGGGGTGTGGATAGTGATC
ATATCGCATTGCAAAATGTCTTCAAAATTTTTCGTGTAAATGACTCCTAAATCAGTGGCTTTTGAAGAAG
GGATATAAGGATCATAGGCTAGAACTTCCATTTCAAAGGCTTTTGCTCTAATGCCCACCCTAGAGCCAAT
ATTCCCAAAACCAATGATGCCCAGCTTTTTATTTTTCAATTCCGTGCCATACCAATCTTCTCTTTTCCAT
AACCTTTGGTGTTTGATTTGATCGTTTGCACAAGGGAACGAACGCACTGCATTGATCAAATGCGCCATGG
TCAATTCCACAGCGGCAATCGTGTTAGCGGTAGGGATATTCATCACTACAATCCCTTTTTGAGAGCAGCT
TTCTAAATCAATATTATCCACTCCCACGCCCGCTCTCACGATGGATTTTAAGTGGGTTAAGGGCTTTAAA
AAATCGCTTGTGATAGGGGTCATGCTGCGAGTGATGAGCGCATCCATGGGAGTGAGTTTTTCTAAAAGCT
CCTTTTTAGGGCATTTGGAATAATCATGCAAGACAATGTCTTTTTGAGCTTCTAAAATTTGAATGCCTTT
AGCATGGATGGGGTCGCAAATGGCTACTTGATACA
Protein Sequence 
>gi|15645025|ref|NP_207195.1| D-3-phosphoglycerate dehydrogenase [Helicobacter pylori 26695] MYQVAICDPIHAKGIQILEAQKDIVLHDYSKCPKKELLEKLTPMDALITRSMTPITSDFLKPLTHLKSIVRAGVGVDNIDLESCSQKGIVVMNIPTANTIAAVELTMAHLINAVRSFPCANDQIKHQRLWKREDWYGTELKNKKLGIIGFGNIGSRVGIRAKAFEMEVLAYDPYIPSSKATDLGVIYTKNFEDILQCDMITIHTPKNKETINMIGAKEIERMKKGVILLNCARGGLYNEDALYEALETKKVRWLGIDVFSKEPGIHNKLLDLPNVYATPHIGANTLESQEEISKQAAQGVMESLRGSSHPHALNLPMQAFDASAKAYLNLAQKLGYFSSQIHKGVCQKIELSLCGEINQFKDALVAFMLVGVLKPVVGDKINYINAPFVAKERGIEIKVSLKESASPYKNMLSLTLNAANGTISVSGTVFEEDILKLTEIDGFHIDIEPKGKMLLFRNTDIPGVIGSVGNAFARHGINIADFRLGRNTQKEALALIIVDEEVSLEVLEELKNIPACLSVHYVVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a HP0397 mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
COG COG0111HE, under H: Coenzyme transport and metabolism; E: Amino acid transport and metabolism
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].