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glnA from Streptococcus pneumoniae Taiwan19F-14

Victor ID 3915
Gene Name glnA from Streptococcus pneumoniae Taiwan19F-14
Sequence Strain (Species/Organism) Streptococcus pneumoniae Taiwan19F-14
NCBI Gene ID 7686610
NCBI Protein GI 225860520
Locus Tag SPT_0539
Protein Accession YP_002742029.1
Other Database IDs UniProtKB-ID: C1CQ07_STRZT
UniRef100: UniRef100_E0TSP1
UniRef90: UniRef90_E0TSP1
UniRef50: UniRef50_D5T5L0
UniParc: UPI0000051475
EMBL: CP000921
EMBL-CDS: ACO23290.1
RefSeq_NT: NC_012469.1
EnsemblGenome: EBSTRG00000077982.
EnsemblGenome_TRS: EBSTRT00000079068
EnsemblGenome_PRO: EBSTRP00000073588
GenomeReviews: CP000921_GR
KEGG: snt:SPT_0539
ProtClustDB: CLSK876973
BioCyc: SPNE487213:SPT_0539-MONOMER
Taxonomy ID 487213
Gene Starting Position 507438
Gene Ending Position 508784
Gene Strand (Orientation) +
Protein Name glutamine synthetase, type I
DNA Sequence 
>gi|225860012:507438-508784 Streptococcus pneumoniae Taiwan19F-14, complete genome
TATGCCAATCACAGCTGCAGATATTCGTCGTGAAGTCAAGGAAAAAAATGTTACCTTTATTCGTCTTATG
TTCTCAGATATTTTGGGAACCATGAAAAACGTCGAAATTCCTGCTACAGATGAACAGTTAGATAAGGTCT
TGTCGAACAAGGTTATGTTTGATGGATCTTCTATTGAAGGTTTTGTACGTATCAATGAGTCGGATATGTA
CTTGTACCCGGACTTGGATACATGGACAGTCTTCCCTTGGGGAGATGAAAATGGAAGTGTTGCAGGTCTG
ATCTGTGATGTTTATACAACAGAAGGTGAACCATTTGCGGGTGACCCTCGTGGTAATTTGAAACGAGCTC
TTCGTCACATGGAAGAAGTTGGATTCAAATCCTTCAACCTTGGTCCAGAGCCAGAATTCTTCCTATTTAA
GTTGGATGAAAATGGGGACCCAACACTTGAAGTGAATGACAAGGGTGGCTACTTTGATTTGGCACCTACT
GACCTTGCGGACAACACACGTCGTGAGATTGTGAATGTCTTGACCAAAATGGGATTTGAAGTAGAAGCGA
GTCACCACGAGGTTGCGGTTGGACAGCATGAGATTGACTTTAAGTACGATGAAGTTCTCCGTGCTTGTGA
TAAGATTCAAATCTTTAAACTTGTTGTTAAAACCATTGCTCGCAAACACGGACTTTACGCAACATTTATG
GCGAAGCCAAAATTTGGTATTGCTGGCTCAGGTATGCACTGTAATATGTCCTTGTTTGATGCAGAAGGAA
ATAACGCCTTCTTTGATCCAAATGATCCAAAAGGAATGCAGTTGTCAGAAACAGCTTACCATTTCCTAGG
CGGTTTGATCAAGCATGCTTACAACTATACTGCCATCATGAACCCAACAGTTAACTCATACAAACGTTTG
GTTCCAGGTTATGAAGCGCCTGTTTACATTGCTTGGGCTGGTCGTAACCGTTCGCCACTTGTGCGCGTAC
CTGCTTCACGTGGTATGGGAACTCGTCTTGAGTTGCGTTCAGTGGATCCAATGGCGAACCCTTACGTTGC
TATGGCTGTTCTTTTGGAAGTTGGTTTGTATGGTATTGAAAATAAAATCGAAGCACCAGCTCCTATCGAA
GAAAATATCTACATCATGACAGCAGAAGAGCGCAAGGAAGCTGGTATTACAGACCTTCCATCAACTCTTC
ACAACGCTTTGAAAGCTTTGACAGAAGATGAAGTGGTTAAAGCTGCTCTCGGAGATCACATCTACACTAG
CTTCCTTGAAGCCAAACGAATCGAATGGGCAAGTTATGCAACCTTCGTTTCACAATGGGAAATTGATAAT
TATTTAGACCTTTACTA
Protein Sequence 
>gi|225860520|ref|YP_002742029.1| glutamine synthetase, type I [Streptococcus pneumoniae Taiwan19F-14] MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLDKVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEGEPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDLAPTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLVVKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAYHFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGTRLELRSVDPMANPYVAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDLPSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: glnA mutant had significantly reduced adhesion to Detroit 562 human pharyngeal epithelial cells (Kloosterman et al., 2006).
COG COG0174E, under E: Amino acid transport and metabolism
References
Kloosterman et al., 2006: Kloosterman TG, Hendriksen WT, Bijlsma JJ, Bootsma HJ, van Hijum SA, Kok J, Hermans PW, Kuipers OP. Regulation of glutamine and glutamate metabolism by GlnR and GlnA in Streptococcus pneumoniae. The Journal of biological chemistry. 2006; 281(35); 25097-25109. [PubMed: 16787930].