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luxS from Streptococcus pneumoniae Taiwan19F-14

Victor ID 3912
Gene Name luxS from Streptococcus pneumoniae Taiwan19F-14
Sequence Strain (Species/Organism) Streptococcus pneumoniae Taiwan19F-14
NCBI Gene ID 7685557
NCBI Protein GI 225860378
Locus Tag SPT_0389
Protein Accession YP_002741887.1
Other Database IDs UniProtKB-ID: LUXS_STRZT
UniRef100: UniRef100_Q04MC2
UniRef90: UniRef90_Q04MC2
UniRef50: UniRef50_Q1JAI5
UniParc: UPI00000513CE
EMBL: CP000921
EMBL-CDS: ACO22927.1
RefSeq_NT: NC_012469.1
EnsemblGenome: EBSTRG00000079045
EnsemblGenome_TRS: EBSTRT00000077709
EnsemblGenome_PRO: EBSTRP00000072711
GenomeReviews: CP000921_GR
KEGG: snt:SPT_0389
OMA: VRIAKTM
ProtClustDB: PRK02260
BioCyc: SPNE487213:SPT_0389-MONOMER
Taxonomy ID 487213
Gene Starting Position 351195
Gene Ending Position 351677
Gene Strand (Orientation) -
Protein Name S-ribosylhomocysteinase LuxS
DNA Sequence 
>gi|225860012:351195-351677 Streptococcus pneumoniae Taiwan19F-14, complete genome
TTTAAATCACATGACGTTCAAAGGCATCATCTGAAATCCCTTGTTCCAAGATGAGTTTTGCCCATTCTTT
AGCAGAGAAGAGGCTGTGGTCCTTGTAGTTTCCGCAAGATTCGATGGTTGTCCCTGGGACATCTTCCCAA
GTAGTAGTTTCAGCGATTTCCTTGAGCGAATCCTTGATAACAGCTGCGATTTTAGCACTGGTGTGACGTC
CCCACATAATCATGTGGAAGCCTGTGCGGCAACCAAATGGTGAACAGTCAATCATGCCGTCAATGCGGGT
ACGGATGAGTTTGGCTAAGAGGTGCTCGATAGTGTGAAGGCCGGCGGTAGGGATAGAGTCTTCGTTTGGT
TGCACCAAGCGAATATCATAATTGGAGATGATGTCTCCTTTTGGTCCTGTTTCTTCCCCAATCAAGCGAA
CATAGGGTGCTTTGACAATGGTGTGGTCAAGTTCAAAACTTTCGACAATAACTTCTTTTGACA
Protein Sequence 
>gi|225860378|ref|YP_002741887.1| S-ribosylhomocysteinase [Streptococcus pneumoniae Taiwan19F-14] MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLVQPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAVIKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: luxS mutant has defective ability to persist in the nasopharyngeal tissues of mice (Joyce et al., 2004).
COG COG1854T, under T: Signal transduction mechanisms
References
Joyce et al., 2004: Joyce EA, Kawale A, Censini S, Kim CC, Covacci A, Falkow S. LuxS is required for persistent pneumococcal carriage and expression of virulence and biosynthesis genes. Infection and immunity. 2004; 72(5); 2964-2975. [PubMed: 15102809].