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pilX

Victor ID 3903
Gene Name pilX
Sequence Strain (Species/Organism) Neisseria meningitidis alpha14
NCBI Gene ID 8222730
NCBI Protein GI 254804754
Locus Tag NMO_0766
Protein Accession YP_003082975.1
Other Database IDs UniProtKB-ID: C6S6E1_NEIML
UniRef100: UniRef100_C6S6E1
UniRef90: UniRef90_C6S6E1
UniRef50: UniRef50_B4RKG6
UniParc: UPI0001B02D38
EMBL: AM889136
EMBL-CDS: CBA05230.1
RefSeq_NT: NC_013016.1
EnsemblGenome: EBNEIG00000013550.
EnsemblGenome_TRS: EBNEIT00000013550
EnsemblGenome_PRO: EBNEIP00000014335
GenomeReviews: AM889136_GR
ProtClustDB: CLSK877804
Taxonomy ID 662598
Gene Starting Position 814226
Gene Ending Position 814825
Gene Strand (Orientation) +
Protein Name type IV pilus assembly protein
DNA Sequence 
>gi|254804028:814226-814825 Neisseria meningitidis alpha14, complete genome
TATGCGCAAACAGAACACTTTGACGGGAATCCCGACTTCTGACGGACAGAGGGGGTTTGCACTGTTTATC
GTGCTGATGGTGATGATCGTCGTGGCTTTTTTGGTTGTAACTGCCGCGCAGTCTTACAATACCGAGCAGC
GGATCAGTGCCAACGAATCAGACAGGAAATTGGCTTTGTCTTTGGCCGAGGCGGCTTTGCGGGAAGGCGA
ACTTCAGGTTTTGGATTTGGAATATGATACGGACAGTAAGGTTACATTTAGCGAAAACTGTGGAGAAGGT
CTGTGTACCGCAGTGAATGTGTGGACAAATACAAATAATGATAATGAAGAGGCTTTTGACAATATCGTGG
TGCAAGGCAAGCCCACCGTTGAGGCGGTGAAGCGTTTTTGCCCTGCAAATTCTACCGACCTGTGCATTGA
CAAGAAAGGGATGGAATATAAGAAAGGCACGAGAAGCGTCAGCAAACCACCGCGCTATATTATCGAATAT
TTGGGCGTGAAGAACGGAGAAAATGTTTATCGGGTTACTGCCAAGGCTTGGGGTAAGAATGCCAATACCG
TGGTCGTCCTTCAATCTTATGTAAGCAATAATGATGAGTA
Protein Sequence 
>gi|254804754|ref|YP_003082975.1| type IV pilus assembly protein [Neisseria meningitidis alpha14] MRKQNTLTGIPTSDGQRGFALFIVLMVMIVVAFLVVTAAQSYNTEQRISANESDRKLALSLAEAALREGELQVLDLEYDTDSKVTFSENCGEGLCTAVNVWTNTNNDNEEAFDNIVVQGKPTVEAVKRFCPANSTDLCIDKKGMEYKKGTRSVSKPPRYIIEYLGVKNGENVYRVTAKAWGKNANTVVVLQSYVSNNDE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pilX mutant had reduced adherence to human epithelial cells (Hélaine et al., 2005).
COG COG4726NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Hélaine et al., 2005: Hélaine S, Carbonnelle E, Prouvensier L, Beretti JL, Nassif X, Pelicic V. PilX, a pilus-associated protein essential for bacterial aggregation, is a key to pilus-facilitated attachment of Neisseria meningitidis to human cells. Molecular microbiology. 2005; 55(1); 65-77. [PubMed: 15612917].