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nadA from Neisseria meningitidis alpha14

Victor ID 3895
Gene Name nadA from Neisseria meningitidis alpha14
Sequence Strain (Species/Organism) Neisseria meningitidis alpha14
NCBI Gene ID 8221962
NCBI Protein GI 254805574
Locus Tag NMO_1648
Protein Accession YP_003083795.1
Other Database IDs UniProtKB-ID: C6S8R6_NEIML
UniRef100: UniRef100_C6S8R6
UniRef90: UniRef90_Q5F6I7
UniRef50: UniRef50_B2UAP5
UniParc: UPI0001B02F3A
EMBL: AM889136
EMBL-CDS: CBA07725.1
RefSeq_NT: NC_013016.1
EnsemblGenome: EBNEIG00000014859.
EnsemblGenome_TRS: EBNEIT00000014859
EnsemblGenome_PRO: EBNEIP00000014195
GenomeReviews: AM889136_GR
ProtClustDB: PRK09375
Taxonomy ID 662598
Gene Starting Position 1783453
Gene Ending Position 1784565
Gene Strand (Orientation) +
Protein Name quinolinate synthetase A
DNA Sequence 
>gi|254804028:1783453-1784565 Neisseria meningitidis alpha14, complete genome
CATGCAAACCGCCGCCCGCCGCTCGTTCGACTACGATATGCCCCTCATCCAAACGCCGACTTCCGCCTGC
CAAATCCGTCAGGCGTGGGCGAAGGTTGCCGATACGCCCGACCACGAGACGGCAGGCCGTCTGAAAGACG
AAATCAAGGCTTTGCTGAAGGAGAAAAACGCGGTCTTGGTGGCGCATTATTACGTCGATCCGCTGATTCA
GGATTTGGCTTTGGAAACGGGCGGATGCGTGGGCGATTCGCTGGAAATGGCGCGCTTCGGTGCGGAACAC
GAAGCCGGTACGCTGGTGGTGGCTGGTGTGCGCTTCATGGGCGAGAGCGCGAAAATCCTCTGCCCTGAAA
AAACGGTGCTGATGCCTGATTTGGAGGCGGAATGTTCTTTGGATTTGGGTTGTCCCGAAGAAGCGTTTTC
AGCGTTTTGCGACCAACACCCCGACCGCACGGTGGTGGTGTACGCCAACACTTCCGCCGCCGTGAAAGCG
CGTGCCGACTGGGTGGTAACGTCTTCGGTGGCGTTGGAAATCGTGTCGTATTTGAAATCGCGCGGCGAGA
AACTGATTTGGGGACCCGACCGCCACCTCGGCGACTACATCCGCCGCGAAACGGGCGCGGATATGCTGTT
GTGGCAGGGTTCGTGCATCGTCCATAACGAATTCAAAGGGCAAGAGCTGGCGGCGTTGAAGGCGGAACAT
CCCGACGCGGTGGTGCTGGTTCATCCCGAATCGCCGCAAAGCGTCATCGAACTGGGCGACGTGGTCGGCT
CGACCAGCAAACTGCTCAAAGCCGCCGTATCGCGTCCTGAAAAAAAATTCATCGTGGCGACCGATTTAGG
CATCCTGCACGAAATGCAAAAGCAGGCGCCCGACAAAGAATTTATCGCCGCACCGACGGCGGGCAACAGC
GGAAGCTGCAAAAGCTGCGCGTTCTGCCCGTGGATGGCGATGAATTCGCTGGGCGGCATCAAATACGCCC
TGACAAGCGGGCACAACGAAATCCTGTTGGACAGAAAGCTGGGCGAAGCCGCCAAACTGCCTTTACAGCG
TATGCTCGACTTCGCGGCAGGACTCAAACGCGGGGATGTGTTCAACGGCATGGGCCCCGCCTG
Protein Sequence 
>gi|254805574|ref|YP_003083795.1| quinolinate synthetase [Neisseria meningitidis alpha14] MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDHETAGRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYIRRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLVHPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKEFIAAPTAGNSGSCKSCAFCPWMAMNSLGGIKYALTSGHNEILLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGPA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: NadA mutation decreases epithelial adhesion of capsulate N. meningitidis and invasion by acapsulate N. meningitidis (Carbonnelle et al., 2009).
COG COG0379H, under H: Coenzyme transport and metabolism
References
Carbonnelle et al., 2009: Carbonnelle E, Hill DJ, Morand P, Griffiths NJ, Bourdoulous S, Murillo I, Nassif X, Virji M. Meningococcal interactions with the host. Vaccine. 2009; 27 Suppl 2; B78-89. [PubMed: 19481311].