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ilvD from Neisseria meningitidis alpha14

Victor ID 3893
Gene Name ilvD from Neisseria meningitidis alpha14
Sequence Strain (Species/Organism) Neisseria meningitidis alpha14
NCBI Gene ID 8221600
NCBI Protein GI 254804977
Locus Tag NMO_1006
Protein Accession YP_003083198.1
Other Database IDs UniProtKB-ID: C6S715_NEIML
UniRef100: UniRef100_C6S715
UniRef90: UniRef90_Q5F8G6
UniRef50: UniRef50_Q5F8G6
UniParc: UPI0001B02BAD
EMBL: AM889136
EMBL-CDS: CBA05904.1
RefSeq_NT: NC_013016.1
EnsemblGenome: EBNEIG00000015098.
EnsemblGenome_TRS: EBNEIT00000015098
EnsemblGenome_PRO: EBNEIP00000013802
GenomeReviews: AM889136_GR
ProtClustDB: PRK12448
Taxonomy ID 662598
Gene Starting Position 1033598
Gene Ending Position 1035457
Gene Strand (Orientation) -
Protein Name dihydroxy-acid dehydratase
DNA Sequence 
>gi|254804028:1033598-1035457 Neisseria meningitidis alpha14, complete genome
CTTATCTTTCGATTTGCGCTACGTCGCGCACCGCGCCTTTGTCGGCGGAAGTCGCCATCGCGCCGTAAGC
TCTTAATGCGACGGAGACGTAGCGGTCGCGGTTTTCCGGTTTCCACGCTTTGCTGCCGCGTGCTTCCATT
TCGGCACGGCGCGCGGCAAGCTCTTCATCGGAAATGACAAGGTGGATGCTGCGGTTGGGGATGTCGATTT
CGACGGTATCGCCTTCGTGTACCAAACCGATCGCGCCACCTTCCGCCGCTTCGGGCGAGGCGTGTCCGAT
GGACAAACCTGATGTGCCGCCGGAAAAGCGTCCGTCGGTCAGGAGGGCACAGGCTTTGCCCAAACCTTTG
GATTTCAGGTAGGAGGTTGGGTACAGCATTTCCTGCATACCCGGGCCGCCTTTCGGGCCTTCGTAGCGGA
TGATGACGATGTCGCCGACGACGATTTGGTTGCCCAAAATGCCTTCTACTGCGTCTTCTTGGCTTTCAAA
CACGCGGGCGCGGCCGGTGAATTTGAGGATGCTCTCATCCACGCCTGCGGTTTTTACCACGCAGCCGCGT
TCGGCGATGTTGCCGAACAAGACCGCCAAACCGCCGTCTTGCGAGTAGGCGTGTGCCACGTCGCGGATAC
AGCCTTTTTCGCGGTCGAGGTCGAGGGTTTTCCACATACGGTTTTGCGAGAACGCTTGGGTGGTGCGTAC
GCCGCCGGGCGCGGCTTTGAAGCGTTCGATGGCGCGGGTGTTTTCAGGGTTGGTTACGTCCCATTTTTCA
ATCGCGTCTTTCAGCGTCGGTGCGTGGATAGTGTGCACGTCGGTGTGCAGTTTGCCCGCTTTGTCCAATT
CTTTCAGGATGGCGAAGATGCCGCCGGCTCGGTGCACGTCTTCCATATAGTAGTCGTGGTTGTTGGGTGC
GGTTTTGCAGATGCAGGGCACGACGCGGCTTAAGCGGTCGATGTCTGCCATTTTGAAATCCACGCCCGCT
TCGTTGGCGACGGCGAGCAAATGCAAAATGGTGTTGGTAGAGCCGCCCATCGCAATGTCCATCGTCATAG
CGTTTTCAAACGCTTTTTTGGTGGCGATGCTGCGCGGCAGCACGGTTTCGTCGTCTTGCTCGTAATAGCG
TTTGGTGATTTCGACAATCATACGTCCTGCTTCGAGGAACAATTCTTTACGGCCTGCGTGGGTCGCCAAA
TACGAACCGTTGCCGGGTAGGGACAGACCGAGTGCTTCGGTCAGGCAGTTCATCGAGTTTGCCGTAAACA
TACCGGAGCAGGAGCCGCAGGTCGGGCAGGCGTTTTGCTCGACTTCTTCGACTTGCCGGTTACTGACATT
GTCGTCCGCCGATTCGATCATCGCGTCAATCAAGTCCAAACGGCGTTCGGGTTGGATGTTTGCCACGCCG
ATGACCTTGCCCGCCTCCATCGGGCCGCCGGAAACGAAGATGGTCGGGATATTCAGGCGCATGGCGGCAA
TCAGCATTCCGGGGGTGATTTTGTCGCAGTTGGAAATGCACACCAGCGCGTCGGCGCAGTGGGCGTTGAC
CATATATTCGATGGAGTCGGCAATCAAATCGCGGCTGGGCAGGGAGTAGAGCATACCGCTGTGTCCCATA
GCGATACCGTCGTCGATGGCTATGGTGTTGAATTCTTTGGCGATTGCACCGGCTTTTTCAATCTCGCGGG
CAACCAGCTGGCCCATATTGTGCAGGTGGACATGGCCGGGCACGAATTGGGTAAAGGAGTTGGCAACGGC
GATAATAGGTTTGCCAAAATCGGTTTCCATCACGCCGGTGGCGCGCCACAATGCGCGTGCACCCGCCATA
TTGCGGCCGTGGGTGGAGGTTTTGGAGCGGTAGTCCGGCA
Protein Sequence 
>gi|254804977|ref|YP_003083198.1| dihydroxy-acid dehydratase [Neisseria meningitidis alpha14] MPDYRSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFTQFVPGHVHLHNMGQLVAREIEKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADALVCISNCDKITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQPERRLDLIDAMIESADDNVSNRQVEEVEQNACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSYLATHAGRKELFLEAGRMIVEITKRYYEQDDETVLPRSIATKKAFENAMTMDIAMGGSTNTILHLLAVANEAGVDFKMADIDRLSRVVPCICKTAPNNHDYYMEDVHRAGGIFAILKELDKAGKLHTDVHTIHAPTLKDAIEKWDVTNPENTRAIERFKAAPGGVRTTQAFSQNRMWKTLDLDREKGCIRDVAHAYSQDGGLAVLFGNIAERGCVVKTAGVDESILKFTGRARVFESQEDAVEGILGNQIVVGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLVHEGDTVEIDIPNRSIHLVISDEELAARRAEMEARGSKAWKPENRDRYVSVALRAYGAMATSADKGAVRDVAQIER
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ilvD mutant is attenuated in rats (Sun et al., 2000).
COG COG0129EG, under E: Amino acid transport and metabolism; G: Carbohydrate transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].