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fhs from Neisseria meningitidis alpha14

Victor ID 3891
Gene Name fhs from Neisseria meningitidis alpha14
Sequence Strain (Species/Organism) Neisseria meningitidis alpha14
NCBI Gene ID 8221210
NCBI Protein GI 254804333
Locus Tag NMO_0323
Protein Accession YP_003082554.1
Other Database IDs UniProtKB-ID: C6S570_NEIML
UniRef100: UniRef100_C6S570
UniRef90: UniRef90_Q5FAG1
UniRef50: UniRef50_Q2RM91
UniParc: UPI0001B02B82
EMBL: AM889136
EMBL-CDS: CBA03958.1
RefSeq_NT: NC_013016.1
EnsemblGenome: EBNEIG00000014676.
EnsemblGenome_TRS: EBNEIT00000014676
EnsemblGenome_PRO: EBNEIP00000013605
GenomeReviews: AM889136_GR
ProtClustDB: PRK13505
Taxonomy ID 662598
Gene Starting Position 342857
Gene Ending Position 344533
Gene Strand (Orientation) +
Protein Name formate--tetrahydrofolate ligase
DNA Sequence 
>gi|254804028:342857-344533 Neisseria meningitidis alpha14, complete genome
CATGAGCTTCAAAACCGATGCCGAAATCGCCCAATCCTCCACCATGCGCCCGATTGGCGAAATTGCCGCC
AAGCTGGGTCTGAACGCCGACAACATTGAGCCTTACGGTCATTACAAGGCGAAAATCAATCCTGCCGAAG
CGTTCAAACTGCCGCAAAAACAGGGCAGGCTGATTTTGGTTACCGCCATCAACCCGACTCCGGCGGGCGA
AGGCAAAACCACCGTAACCATCGGTTTGGCGGACGCGTTGCGCCACATCGGCAAAGATGCCGTGATTGCC
CTGCGCGAACCTTCTCTGGGGCCGGTGTTCGGCGTGAAAGGCGGCGCGGCAGGCGGCGGCTATGCCCAAG
TTTTGCCGATGGAAGACATCAACCTGCACTTCACCAGCGACTTTCACGCCATCGGTGCGGCGAATAACCT
GCTCGCTGCCATGCTCGACAACCATATCTACCAAGGCAACGAGTTGAACATCGACCCCAAACGCGTGCTG
TGGCGGCGCGTGGTCGATATGAACGACCGCCAGTTGCGCAACATCATCGACGGCATGGGTAAACCTGTTG
ACGGTGTGATGCGCCCCGACGGTTTCGACATTACCGTTGCCTCCGAAGTGATGGCGGTATTCTGTCTCGC
CAAAGACATCGGCGATTTGAAAGAGCGTTTGGGCAACATCCTCGTCGCCTACGCCAAAGACGGCAGCCCC
GTTTATGCCAAAGATTTGAAGGCACACGGCGCGATGGCGGCATTGCTTAAAGATGCGATTAAGCCCAACT
TGGTGCAAACCATCGAAGGCACGCCCGCCTTCGTACACGGCGGCCCGTTCGCCAACATCGCCCACGGCTG
CAACTCCGTAACCGCAACCCGTTTGGCGAAACATCTTGCCGATTATGCCGTAACCGAAGCAGGCTTCGGC
GCAGATTTGGGCGCGGAAAAATTCTGCGACATCAAATGCCGTCTGGCGGATTTGAAACCTGATGCGGCTG
TTGTCGTCGCCACTGTCCGCGCTTTGAAATACAACGGCGGCGTGGAACGCGCCAACCTCGGCGAAGAAAA
CCTCGAAGCCTTGGCAAAAGGCCTGCCTAATCTCTTGAAACACATTTCCAACCTGAAAAACGTATTCGGA
CTGCCCGTCGTCGTCGCGCTCAACCGCTTCGTGTCCGACTCCGATGCCGAGTTGGCGATGATTGAAAAAG
CCTGTGCCGAACACGGCGTTGAAGTTTCCCTGACCGAAGTGTGGGGCAAAGGTGGTGCGGGCGGCGCGGA
TTTGGCGCGCAAAGTCGTCAACGCCATTGAAAGTCAAACCAATAACTTCGGTTTCGCCTACGATGTCGAG
TTGGGCATCAAAGACAAAATCCGTGTGATTGCCCAAAAAGTGTACGGCGCGGAAGATGTTGATTTCAGCG
CGGAAGCGTCTGCCGAAATCGCCTCGCTGGAAAAACTGGGCTTGGACAAAATGCCGATTTGCATGGCGAA
AACCCAATATTCTTTGAGCGACAACGCCAAACTGTTGGGCTGCCCCGAAGGCTTCCGCATCGCCGTGCGC
GGCATCACCGTTTCCGCCGGCGCGGGCTTCATCGTCGCGCTGTGCGGCAATATGATGAAGATGCCGGGTC
TGCCGAAAGTGCCGGCCGCCGAGAAAATCGATGTGGACGAACACGGCGTGATTCACGGCTTGTTCTG
Protein Sequence 
>gi|254804333|ref|YP_003082554.1| formate--tetrahydrofolate ligase [Neisseria meningitidis alpha14] MSFKTDAEIAQSSTMRPIGEIAAKLGLNADNIEPYGHYKAKINPAEAFKLPQKQGRLILVTAINPTPAGEGKTTVTIGLADALRHIGKDAVIALREPSLGPVFGVKGGAAGGGYAQVLPMEDINLHFTSDFHAIGAANNLLAAMLDNHIYQGNELNIDPKRVLWRRVVDMNDRQLRNIIDGMGKPVDGVMRPDGFDITVASEVMAVFCLAKDIGDLKERLGNILVAYAKDGSPVYAKDLKAHGAMAALLKDAIKPNLVQTIEGTPAFVHGGPFANIAHGCNSVTATRLAKHLADYAVTEAGFGADLGAEKFCDIKCRLADLKPDAAVVVATVRALKYNGGVERANLGEENLEALAKGLPNLLKHISNLKNVFGLPVVVALNRFVSDSDAELAMIEKACAEHGVEVSLTEVWGKGGAGGADLARKVVNAIESQTNNFGFAYDVELGIKDKIRVIAQKVYGAEDVDFSAEASAEIASLEKLGLDKMPICMAKTQYSLSDNAKLLGCPEGFRIAVRGITVSAGAGFIVALCGNMMKMPGLPKVPAAEKIDVDEHGVIHGLF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: fhs mutant is attenuated in rats (Sun et al., 2000).
COG COG2759F, under F: Nucleotide transport and metabolism
References
Sun et al., 2000: Sun YH, Bakshi S, Chalmers R, Tang CM. Functional genomics of Neisseria meningitidis pathogenesis. Nature medicine. 2000; 6(11); 1269-1273. [PubMed: 11062540].