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hrpA from Neisseria meningitidis alpha14

Victor ID 3889
Gene Name hrpA from Neisseria meningitidis alpha14
Sequence Strain (Species/Organism) Neisseria meningitidis alpha14
NCBI Gene ID 8221120
NCBI Protein GI 254804179
Locus Tag NMO_0159
Protein Accession YP_003082400.1
Other Database IDs UniProtKB-ID: C6S4R6_NEIML
UniRef100: UniRef100_C6S4R6
UniRef90: UniRef90_B4RJD6
UniRef50: UniRef50_A9M0L3
UniParc: UPI0001B02DD6
EMBL: AM889136
EMBL-CDS: CBA03608.1
RefSeq_NT: NC_013016.1
EnsemblGenome: EBNEIG00000013871.
EnsemblGenome_TRS: EBNEIT00000013871
EnsemblGenome_PRO: EBNEIP00000012611
GenomeReviews: AM889136_GR
ProtClustDB: CLSK878438
Taxonomy ID 662598
Gene Starting Position 159079
Gene Ending Position 160566
Gene Strand (Orientation) -
Protein Name ATP-dependent helicase
DNA Sequence 
>gi|254804028:159079-160566 Neisseria meningitidis alpha14, complete genome
TTCAGGCGGCCTCCACTGCCCCTAATTCCAGCAACACCTGAAACCCATCATTAATATACCTCGAATCGGG
CATTTCTAAAAATGGGAATGCCGCTACGTCGCCGAGTTTCAGCGATGCCATGCGCAGGATGACGGCGGCG
AGGTTGCTGCGGGCGATTTCGGGGTCGGTAAATTCGGGGCGGTTGTTGAAATTTTCTTCTGAAAACAATC
GGATACATACGCCTGCGGAGACGCGTCCGCAGCGGCCGGAGCGTTGGTGGGCGGCGGCTTGGGAGATTTT
TTCGATATGAAGCTGCTCCACTTTCGCCCGTGCGGAATAGCGTTTGACGCGTGCGAGGCCGGTGTCGATG
ACGTATTTGATGCCCGGCACGGTAAGCGAGGTTTCGGCGACGTTGGTTGCCAGCACGATGCGGCGTTTCG
CTCCGGAGGGGTGAAAGATTTTGTGCTGCTCGGCGTGCGACAGGCGTGCGAACAGGGGCAGGATTTCGTC
GTTGCGGCGTAGCGTGGATTTGCGCAGGGCTTCGGCGGCTTCGCGGATTTCGCGTTCGCCCGGCAGGAAT
ACCAAAATATCGCCTTCGCCATATTGCGCCAATTCGTCCGCCGCATCGACAATCGCGTCGGTCAGCTCGA
CTTCTGCGTCGTCTTCGTCTTTGCCGGTCAGCGGGCTGTAGAGGATTTCGACGGGATAGGTGCGCCCGCT
CACTTCTAAAACGGGCGCGCCGTTGAAGTGTCGGGAGAAGCCTTCTGTGTCTATCGTTGCCGAGGTGATG
ATAACTTTCAAATCGGGGCGGCGCGGCAGGAGTTGTTTCAAATAGCCCAAAAGGAAGTCGATGTTCAGGC
TGCGCTCGTGCGCTTCGTCGATGATAATCGTGTCGTAGGCGGCGAGATAACGGTCGGTCTGGGTTTCCGC
CAGCAGGATGCCGTCGGTCATCAGCTTGACGCAGGCATCGCGCGAGGTGTGGTCGGTGAAGCGCACTTTA
TAGCCGACCGCGCTGCCGATTTCGGATTTCAGCTCTTCGGCAATCCGCTCTGCTACGGAACGCGCCGCCA
AACGGCGCGGCTGGGTATGCCCGATCAAACCCGCCGCCCCGCGCCCGAGTTCCAGACAAATCTTGGGCAA
CTGAGTGGTCTTGCCCGAACCGGTTTCGCCGCAAATAATCGTTACCTGATGTTCGGCAACGGTTTTTTTG
ATTTCGTCAAGTTTTTCGTGAACGGGCAGGGTGTTGTCGAATTCGGGTTTGGGCAAGGCGGCCAAACGTT
TCAAAAAGATTTCGTGCGATTTTCGGTATTTTTCTTCGACTTTGGACAAGCCGCCGTATTTGTTGGGATT
TTTGAAGGCGGATTGCAGGAAGTGGCGGTCTTTGGAGAGGGTTTGGGAGAAATCGGGAAACATGATTGGT
GCGTATGCGGTAAAAAATAGAATTATAGCAAACGCTTTGGTTGGGTTCGGGCAATATCGGGATGGGGAAA
TGCCGTCTGAAAACCGCA
Protein Sequence 
>gi|254804179|ref|YP_003082400.1| ATP-dependent helicase [Neisseria meningitidis alpha14] MRFSDGISPSRYCPNPTKAFAIILFFTAYAPIMFPDFSQTLSKDRHFLQSAFKNPNKYGGLSKVEEKYRKSHEIFLKRLAALPKPEFDNTLPVHEKLDEIKKTVAEHQVTIICGETGSGKTTQLPKICLELGRGAAGLIGHTQPRRLAARSVAERIAEELKSEIGSAVGYKVRFTDHTSRDACVKLMTDGILLAETQTDRYLAAYDTIIIDEAHERSLNIDFLLGYLKQLLPRRPDLKVIITSATIDTEGFSRHFNGAPVLEVSGRTYPVEILYSPLTGKDEDDAEVELTDAIVDAADELAQYGEGDILVFLPGEREIREAAEALRKSTLRRNDEILPLFARLSHAEQHKIFHPSGAKRRIVLATNVAETSLTVPGIKYVIDTGLARVKRYSARAKVEQLHIEKISQAAAHQRSGRCGRVSAGVCIRLFSEENFNNRPEFTDPEIARSNLAAVILRMASLKLGDVAAFPFLEMPDSRYINDGFQVLLELGAVEAA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hrpA mutant was deficient in the ability to grow/live in HeLa cells (Talà et al., 2008).
COG COG1643L, under L: Replication, recombination and repair
References
Talà et al., 2008: Talà A, Progida C, De Stefano M, Cogli L, Spinosa MR, Bucci C, Alifano P. The HrpB-HrpA two-partner secretion system is essential for intracellular survival of Neisseria meningitidis. Cellular microbiology. 2008; 10(12); 2461-2482. [PubMed: 18680551].