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HP0073

Victor ID 388
Gene Name HP0073
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 900171
NCBI Protein GI 15644703
Locus Tag HP0073
Protein Accession NP_206873.1
Other Database IDs UniProtKB-ID: URE23_HELPY
UniRef100: UniRef100_B6JPH6
UniRef90: UniRef90_B6JPH6
UniRef50: UniRef50_B6JPH6
UniParc: UPI000002C3CD
EMBL: X17079
EMBL: M60398
EMBL: AB032429
EMBL: AE000511
EMBL-CDS: CAA34932.1
EMBL-CDS: AAA25020.1
EMBL-CDS: BAA84532.1
EMBL-CDS: AAD07144.1
RefSeq_NT: NC_000915.1
PDB: 1E9Y
PDB: 1E9Z
DIP: DIP-3146N
MINT: MINT-180633
GenomeReviews: AE000511_GR
KEGG: hpy:HP0073
NMPDR: fig|85962.1.peg.71
TIGR: HP_0073
HOGENOM: HBG365918
OMA: VHHPIRG
ProtClustDB: PRK13986
Taxonomy ID 85962
Gene Starting Position 77239
Gene Ending Position 77955
Gene Strand (Orientation) -
Protein Name bifunctional urease subunit gamma/beta
DNA Sequence 
>gi|15644634:77239-77955 Helicobacter pylori 26695, complete genome
CTTACTCCTTAATTGTTTTTACATAGTTGTCATCGCTTTTAGCGCCATGAAAACCACGCTCTTTAGCTCT
GTGTAAAGCAATTTTTTTGCTTTCGTTGTCTGCTTGCCTATCAACCAACGCGTTAAATCCAAAGATTCTT
CTGTTACCGCCAATGTCAATCAATTCTACGGATTTTTCTTCGCCAGGCTCAAACCTTACCGCTGTCCCGC
TCGCAATGTCTAAGCGTTTACCGAAAGTTTTTTCTCTGTCAAAGTCTAAGCATCTATTCACTTCAAAGAA
ATGGAAGTGTGAGCCGATTTGAACCGGTCTGTCGCCAACATTTTTAACTTTCACGCTAACGGCTTTTTTG
CCTTCGTTGATAGTGATGTCTTCATTTTTTAAGAACAACTCACCAGGAACTAATTTACCATTGGCCTCAA
TAGGGGTATGCACGGTTACGAGTTTTGTCCCATCAGGAAACATCGCTTCAATACCCACTTCATGGATCAT
GCTTGCCACGCCATCCATCACATCATCCGGTTTTAAAAGAGTGCGCCCTTCTTGCATCAATTCAGCCGCA
GTCTTTTTACCAGCTCTCGCTTCTTCCATAATATGGGCACTAATCAAAGCTACCGCTTCTACATAGTTAA
GCTTAATGCCTTTTTCTTTGCGTTTTTTAGCCAATTCTCCAGCATAGTGGAGCATCAACTTGTCTAACTC
TTTTGGGGTGAGTTTCA
Protein Sequence 
>gi|15644703|ref|NP_206873.1| urease subunit alpha [Helicobacter pylori 26695] MKLTPKELDKLMLHYAGELAKKRKEKGIKLNYVEAVALISAHIMEEARAGKKTAAELMQEGRTLLKPDDVMDGVASMIHEVGIEAMFPDGTKLVTVHTPIEANGKLVPGELFLKNEDITINEGKKAVSVKVKNVGDRPVQIGSHFHFFEVNRCLDFDREKTFGKRLDIASGTAVRFEPGEEKSVELIDIGGNRRIFGFNALVDRQADNESKKIALHRAKERGFHGAKSDDNYVKTIKE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a HP0073 mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
COG COG0832E, under E: Amino acid transport and metabolism
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].