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HP0486

Victor ID 385
Gene Name HP0486
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 900059
NCBI Protein GI 15645113
Locus Tag HP0486
Protein Accession NP_207283.1
Other Database IDs UniProtKB-ID: O25230_HELPY
UniRef100: UniRef100_O25230
UniRef90: UniRef90_B2USU8
UniRef50: UniRef50_Q17XW8
UniParc: UPI00000C084E
EMBL: AE000511
EMBL-CDS: AAD07554.1
RefSeq_NT: NC_000915.1
DIP: DIP-3318N
MINT: MINT-181327
GenomeReviews: AE000511_GR
KEGG: hpy:HP0486
NMPDR: fig|85962.1.peg.481
TIGR: HP_0486
HOGENOM: HBG501710
OMA: YPANAYL
ProtClustDB: CLSK496064
Taxonomy ID 85962
Gene Starting Position 509351
Gene Ending Position 510937
Gene Strand (Orientation) +
Protein Name hypothetical protein
DNA Sequence 
>gi|15644634:509351-510937 Helicobacter pylori 26695, complete genome
AATGAAATTAAAGAAACGAAAAGTTGCGGCTGCATTGCTAAAGCGTTTTACCTTGCCACTATTGTTCACT
ACGGGTTCATTAGGGGCGGTTACTTATGAAGTGCATGGAGATTTTATCAATTTTGCTAAAGTGGGTTTTA
ACCATTCGCCCATTAATCCTGTTAAAGGTATCTATCCCACAGAAACTTTTGTTAACCTTACGGGTAAGCT
AGAGGGGTCTGTGCATTTAGGTAGGGGATGGACCGTGAATTTAGGCGGTGTTTTGGGCGGACAGGCTTAT
GATGGCACTAAGTATGATAGGTGGGCGAAGGATTTTACCCCCCCAAGCTATTGGGATAAAACTTCTTGCG
GTACTGATTCTATGAGTCTTTGTATGAATGCCACTAAAATGTGGCAGCAATCAGGGCCAGGTGGCGTCAT
TAACCCTAGAGGTATTGGTTGGGAATACATGGGTGAGTGGAACGGCTTGTTCCCTAACTACTATCCGGCT
AACGCCTACTTGCCTGGTGGCTCAAGGCGCTATCAAGTCTATAAAGCAAATTTGACCTATGATAGCGACA
GGGTCCATATGGTAATGGGGCGTTTTGACATTACCGAGCAGGAGCAAATGGATTGGATTTACCAATTGTT
CCAAGGGTTTTATGGGACTTTCAAGCTCACTAAGAATATGAAATTCTTGCTCTTTAGTGGTTGGGGTCGT
GGTATCGCTGATGGTCAGTGGTTGTTCCCTATCTATCGTGAAAAGCCTTGGGGGGTTCATAAAGCGGGTA
TTATTTATCGCCCTACAAAGAATTTGATGATCCACCCTTATGTGTATCTTATCCCAATGGTAGGCACATT
GCCTGGTGCTAAAATAGAATACGATACCAATCCTGAATTTAGCGGTAGGGGCATTAGGAACAGAACGACT
TTCTATGCGTTGTATGACTATCGTTGGAATAACGCTGAATACGGTCGTTACGCGCCCGCTCGTTATAACA
CTTGGGATCCGTTCTTGGATAATGGTAAGTGGCGTGGCTTGCAAGGTCCTGGTGGTGCGACGCTCCTTTT
ACGCCACCATATAGATATTAACAACTACTTTGTGGTTGGTGGTGCTTATCTCAACATTGGTAACCCTAAC
ATGAACTTAGGTACTTGGGGTAACCCTGTGGCTGTTGATGGTATCGAACAATGGGTCGGTAGTATCTATA
GCTTAGGGTTTGCGGGGATTGACAACATTACCGATGCTGACGCGTTCACCGAGTATGTTAAAGGTGGAGG
CAAGCATGGTAAGTTTAGTTGGAGCGTTTATCAGCGCTTCACTACCGCTCCAAGGGCTTTGGAATATGGT
ATCGGTATGTATCTAGACTATCAGTTCAGCAAGCATGTTAAAGCGGGTCTCAAACTCGTATGGTTAGAGT
TCCAAATTCGTGCGGGTTACAACCCTGGAACCGGTTTCCTTGGGCCAAACGGTCAGCCGCTTAACTTGAA
TACTGGTTTGTTTGAGTCTTCAGCGTTCGCTCAAGGCCCTCAAAACATGGGCGGTATCGCAAAAAGCATC
ACTCAAGACAGAAGCCATTTGATGACACACATTAGTTATAGTTTCTA
Protein Sequence 
>gi|15645113|ref|NP_207283.1| hypothetical protein HP0486 [Helicobacter pylori 26695] MKLKKRKVAAALLKRFTLPLLFTTGSLGAVTYEVHGDFINFAKVGFNHSPINPVKGIYPTETFVNLTGKLEGSVHLGRGWTVNLGGVLGGQAYDGTKYDRWAKDFTPPSYWDKTSCGTDSMSLCMNATKMWQQSGPGGVINPRGIGWEYMGEWNGLFPNYYPANAYLPGGSRRYQVYKANLTYDSDRVHMVMGRFDITEQEQMDWIYQLFQGFYGTFKLTKNMKFLLFSGWGRGIADGQWLFPIYREKPWGVHKAGIIYRPTKNLMIHPYVYLIPMVGTLPGAKIEYDTNPEFSGRGIRNRTTFYALYDYRWNNAEYGRYAPARYNTWDPFLDNGKWRGLQGPGGATLLLRHHIDINNYFVVGGAYLNIGNPNMNLGTWGNPVAVDGIEQWVGSIYSLGFAGIDNITDADAFTEYVKGGGKHGKFSWSVYQRFTTAPRALEYGIGMYLDYQFSKHVKAGLKLVWLEFQIRAGYNPGTGFLGPNGQPLNLNTGLFESSAFAQGPQNMGGIAKSITQDRSHLMTHISYSF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: a HP0486 mutant was attenuated for gastric colonization in a gerbil model (Kavermann et al., 2003)
References
Kavermann et al., 2003: Kavermann H, Burns BP, Angermuller K, Odenbreit S, Fischer W, Melchers K, Haas R. Identification and characterization of Helicobacter pylori genes essential for gastric colonization. The Journal of experimental medicine. 2003; 197(7); 813-822. [PubMed: 12668646].