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spvC from Salmonella enterica subsp. enterica serovar Paratyphi C strain RKS4594

Victor ID 3840
Gene Name spvC from Salmonella enterica subsp. enterica serovar Paratyphi C strain RKS4594
Sequence Strain (Species/Organism) Salmonella enterica subsp. enterica serovar Paratyphi C strain RKS4594
NCBI Gene ID 7552348
NCBI Protein GI 224504239
Locus Tag SPC_p004
Protein Accession YP_002635578.1
Other Database IDs UniProtKB-ID: C0Q8H1_SALPC
UniRef100: UniRef100_C0Q8H1
UniRef90: UniRef90_P15805
UniRef50: UniRef50_Q327I2
UniParc: UPI000195111D
EMBL: CP000858
EMBL-CDS: ACN48777.1
RefSeq_NT: NC_012124.1
GenomeReviews: CP000858_GR
KEGG: sei:SPC_p004
ProtClustDB: CLSK862802
Taxonomy ID 476213
Plasmid No pSPCV
Gene Starting Position 4410
Gene Ending Position 5129
Gene Strand (Orientation) +
Protein Name SpvC
DNA Sequence 
>gi|224504235:4410-5129 Salmonella enterica subsp. enterica serovar Paratyphi C strain RKS4594 plasmid pSPCV, complete sequence
CATGCCCATAAATAGGCCTAATCTAAACATCCCTCCTTTGAATATTGTAGCTGCTTATGATGGGGCGGAA
ATACCATCTACAAATAAGCACCTGAAAAATAATTTCAACTCCTTGCACAACCAAATGCGGAAGATGCCGG
TATCCCACTTTAAAGAGGCGCTGGATGTGCCTGACTATTCAGGGATGCGCCAGAGTGGTTTCTTTGCTAT
GAGCCAAGGTTTTCAGCTGAATAACCATGGTTACGATGTTTTCATCCATGCTCGTCGAGAATCACCTCAG
TCTCAGGGCAAATTTGCCGGTGACAAGTTCCACATCAGTGTGCTCAGGGATATGGTGCCACAAGCATTTC
AAGCGCTGTCCGGATTGCTGTTTTCAGAGGACAGTCCGGTAGATAAGTGGAAAGTGACCGATATGGAGAA
GGTCGTTCAACAAGCCCGTGTTAGCCTGGGCGCTCAGTTCACGTTGTATATAAAACCAGACCAGGAAAAT
TCGCAGTACAGTGCGTCGTTTCTCCACAAGACACGGCAATTTATAGAGTGTCTGGAATCCAGACTATCCG
AAAATGGGGTTATTTCAGGACAGTGTCCTGAGTCAGACGTTCATCCTGAAAATTGGAAATATCTCAGTTA
TCGTAATGAACTACGAAGTGGGCGTGATGGTGGTGAAATGCAGAGACAGGCTTTACGTGAGGAACCGTTT
TATCGTTTGATGACAGAGTA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The spvBC-bearing plasmid was capable of replacing all of the spv genes, as well as the entire virulence plasmid, of serovar Typhimurium for causing systemic infection in BALB/c mice after subcutaneous, but not oral, inoculation. A point mutation in the spvBC plasmid preventing translation but not transcription of spvC eliminated the ability of the plasmid to confer virulence (Matsui et al., 2001).
References
Matsui et al., 2001: Matsui H, Bacot CM, Garlington WA, Doyle TJ, Roberts S, Gulig PA. Virulence plasmid-borne spvB and spvC genes can replace the 90-kilobase plasmid in conferring virulence to Salmonella enterica serovar Typhimurium in subcutaneously inoculated mice. Journal of bacteriology. 2001; 183(15); 4652-4658. [PubMed: 11443102].