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clpP from Listeria monocytogenes serotype 4b str. CLIP 80459

Victor ID 3824
Gene Name clpP from Listeria monocytogenes serotype 4b str. CLIP 80459
Sequence Strain (Species/Organism) Listeria monocytogenes serotype 4b str. CLIP 80459
NCBI Gene ID 7704098
NCBI Protein GI 226225016
Locus Tag Lm4b_02437
Protein Accession YP_002759123.1
Taxonomy ID 634178
Gene Starting Position 2514751
Gene Ending Position 2515383
Gene Strand (Orientation) +
Protein Name ATP-dependent Clp protease proteolytic subunit
DNA Sequence 
>gi|226222639:2514751-2515383 Listeria monocytogenes Clip81459, complete genome
TATGAACTTAATTCCAACAGTAATCGAACAAACTAGCCGCGGTGAACGTGCATATGACATTTATTCCCGT
TTATTAAAAGACAGAATTATTATGTTAGGATCTGCAATTGATGATAACGTGGCGAATTCGATCGTTTCTC
AATTACTCTTCTTAGATGCACAAGATCCTGAAAAAGATATTTTCCTATATATCAATTCACCAGGTGGAAG
TATTTCAGCTGGTATGGCCATTTACGATACAATGAATTTCGTTAAAGCGGACGTACAAACTATCGGCATG
GGTATGGCAGCTTCCATGGGCTCATTCTTACTAACAGCTGGTGCAAATGGCAAACGGTTTGCCTTGCCAA
ACGCTGAAATTATGATTCACCAACCACTTGGTGGCGCTCAAGGTCAAGCGACTGAAATCGAAATCGCTGC
TCGCCACATTTTAAAAATCAAAGAACGTATGAATACGATTATGGCTGAGAAAACTGGTCAACCGTATGAA
GTCATTGCTCGTGATACAGATCGTGATAATTTCATGACTGCACAAGAAGCAAAAGATTACGGCTTAATTG
ATGATATCATCATTAACAAATCTGGCTTAAAAGGCTAATAAAAAAAAGAGGTTTTGCACAAAATGCAAAA
CCT
Protein Sequence 
>gi|226225016|ref|YP_002759123.1| ATP-dependent Clp protease proteolytic subunit [Listeria monocytogenes serotype 4b str. CLIP 80459] MNLIPTVIEQTSRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLDAQDPEKDIFLYINSPGGSISAGMAIYDTMNFVKADVQTIGMGMAASMGSFLLTAGANGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILKIKERMNTIMAEKTGQPYEVIARDTDRDNFMTAQEAKDYGLIDDIIINKSGLKG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant strain showed reduced bacterial escape from phagosomes of macrophages and virulence in mice (Gaillot et al., 2000).
COG COG0740OU, under O: Posttranslational modification, protein turnover, chaperones; U: Intracellular trafficking, secretion, and vesicular transport
References
Gaillot et al., 2000: Gaillot O, Pellegrini E, Bregenholt S, Nair S, Berche P. The ClpP serine protease is essential for the intracellular parasitism and virulence of Listeria monocytogenes. Molecular microbiology. 2000; 35(6); 1286-1294. [PubMed: 10760131].