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Lm4b_00320

Victor ID 3820
Gene Name Lm4b_00320
Sequence Strain (Species/Organism) Listeria monocytogenes serotype 4b str. CLIP 80459
NCBI Gene ID 7703714
NCBI Protein GI 226222928
Locus Tag Lm4b_00320
Protein Accession YP_002757035.1
Taxonomy ID 634178
Gene Starting Position 324620
Gene Ending Position 326157
Gene Strand (Orientation) +
Protein Name heat-shock protein htrA serine protease
DNA Sequence 
>gi|226222639:324620-326157 Listeria monocytogenes Clip81459, complete genome
CATGGACGAGAAAGAAAAGAATTTAAATGAAAACAGCGAGAATGAAAGCACGCCAAAAAGAGAGGTCGAG
GATACTTTACATACACCGGAGAGCGCGCAACCAGTCCAAGAAACTCCTATTGTAGAAGGCGTGACCCCAG
AAGGGGAGAAATTTGCCGGAGCGACAGAAGATGCAGCCGAGGCGAGTTCTACAAATGCATTTTTTGAAGA
AGCAAGTAATAAAGAACCAGAACCTGCTAGACCGGCTCCAGGGCCAAGACGCGCTGGTACAACTGGTGGC
GGGGCAGTTCCACCTAATAGAGTGAATAATGGCGGAAGTGGTAACGGGAATGGTGAACCACCGAAACGCG
GCAAACACTTTATCGGTTACTTTTTAACAGCACTTATTGGTGTTATTATCGGAGGACTTATTATTTTCTT
TGTCGCTTGGGATAATGGTGACAATGCAGATACAACTTCAAACTCAAATAATAAAGCTACCAAAGTAGAA
AAAGTTTCAGTAGATACAACATCAGATGTAACAAAAGCAGTAGACAAAGTACAAGATGCGGTAGTGAGTG
TTCTAAATTACCAATCATCTTCATCCCTTGATGGAACAACGACTTCTGAACAAGAAGCTTCCTCAGGATC
TGGTGTTATTTATAAAAAGGCAAATGGAAAAGCCTACATCGTAACAAATAATCACGTTGTTGCTGATGCA
AATAAATTAGAAGTAACTTTTACAAACGGTAAAAAATCCGAAGCAAAATTACTAGGGACAGACGAATGGA
ACGATTTAGCTGTTCTTGAAATTGATGATAAAAATGTTACTACAGTCGCTGCATTCGGCGATTCAGATTC
ATTAAAACTTGGTGAACCAGCAATTGCAATTGGTAGCCCACTAGGAACAGAATTTTCCGGTTCTGTAACA
CAAGGTATTATTTCTGGTCTAAACCGTGCAGTACCAGTTGATACAAATGGCGACGGAACAGAAGACTGGG
AAGCAGATGTTATCCAAACAGATGCAGCAATTAACCCTGGTAACAGTGGTGGAGCTTTAATTAATATTGA
AGGCCAAGTAATTGGTATTAACTCAATGAAAATTTCGATGGAAAATGTAGAAGGTATTAGCTTTGCAATT
CCAAGTAACACAGTAGAACCAATCATCGAACAACTAGAAACAAAAGGCGAAGTAGAACGTCCATCTCTAG
GCGTATCCTTACGTGATGTTGATACAATTCCAGAAACACAACAAAAAAATATCTTGAAATTACCTGATAG
CGTAGATTACGGCGCAATGGTACAACAAGTAGTATCCGGTTCTGCAGCAGACAAAGCAGGCTTGAAACAA
TACGATGTTATTGTTGAACTAAACGGCCAAAAAGTAACAAACTCCATGACATTACGCAAAATTCTATACG
GTAACGACGTGAAAATTGGCGATAAAGTCAAAGTGAAATACTATCGTGACGGTAAAGAAAAATCCACAGA
TATTAAATTAGAAGCAGCAAAAACAACCACATGATAACAAAAAGCCATTCTCTTGAAAAAGAGGGTGG
Protein Sequence 
>gi|226222928|ref|YP_002757035.1| heat-shock protein htrA serine protease [Listeria monocytogenes serotype 4b str. CLIP 80459] MDEKEKNLNENSENESTPKREVEDTLHTPESAQPVQETPIVEGVTPEGEKFAGATEDAAEASSTNAFFEEASNKEPEPARPAPGPRRAGTTGGGAVPPNRVNNGGSGNGNGEPPKRGKHFIGYFLTALIGVIIGGLIIFFVAWDNGDNADTTSNSNNKATKVEKVSVDTTSDVTKAVDKVQDAVVSVLNYQSSSSLDGTTTSEQEASSGSGVIYKKANGKAYIVTNNHVVADANKLEVTFTNGKKSEAKLLGTDEWNDLAVLEIDDKNVTTVAAFGDSDSLKLGEPAIAIGSPLGTEFSGSVTQGIISGLNRAVPVDTNGDGTEDWEADVIQTDAAINPGNSGGALINIEGQVIGINSMKISMENVEGISFAIPSNTVEPIIEQLETKGEVERPSLGVSLRDVDTIPETQQKNILKLPDSVDYGAMVQQVVSGSAADKAGLKQYDVIVELNGQKVTNSMTLRKILYGNDVKIGDKVKVKYYRDGKEKSTDIKLEAAKTTT
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Wilson et al., 2006).
COG COG0265O, under O: Posttranslational modification, protein turnover, chaperones
References
Wilson et al., 2006: Wilson RL, Brown LL, Kirkwood-Watts D, Warren TK, Lund SA, King DS, Jones KF, Hruby DE. Listeria monocytogenes 10403S HtrA is necessary for resistance to cellular stress and virulence. Infection and immunity. 2006; 74(1); 765-768. [PubMed: 16369036].