Victors

clpC from Listeria monocytogenes serotype 4b str. CLIP 80459
Victor ID	3819
Gene Name	clpC from Listeria monocytogenes serotype 4b str. CLIP 80459
Sequence Strain (Species/Organism)	Listeria monocytogenes serotype 4b str. CLIP 80459
NCBI Gene ID	7703657
NCBI Protein GI	226222861
Locus Tag	Lm4b_00252
Protein Accession	YP_002756968.1
Taxonomy ID	634178
Gene Starting Position	247196
Gene Ending Position	249693
Gene Strand (Orientation)	+
Protein Name	endopeptidase Clp ATP-binding chain C
DNA Sequence	>gi\|226222639:247196-249693 Listeria monocytogenes Clip81459, complete genome AATGATGTTTGGACGATTTACGCAAAGAGCTCAGAAAGTACTCGCGTTGTCACAAGAAGAGGCGATGCGT TTGAATCATAGTAATTTAGGAACAGAACATATTTTATTAGGGCTTGTAAGAGAAGGCGAAGGAATTGCGG CAAAAGCTCTCTATGAACTGGGAATTAGTTCTGAAAAAGTGCAGCAAGAGGTAGAAGGATTAATTGGTCA TGGGGAAAAAGCTGTGACGACGATCCAATATACACCTCGTGCGAAAAAAGTAATTGAACTGTCCATGGAT GAGGCTCGTAAATTAGGGCATACTTATGTTGGAACAGAACATATCTTACTGGGGCTTATTCGTGAAGGCG AAGGAGTTGCGGCTCGAGTTTTAAGTAATCTTGGTATTAGTTTGAATAAAGCTCGTCAGCAAGTTTTACA GCTCTTAGGCGGCGGGGATGCTACTGGGGCAGGAAGACAAACAAATACACAGGCTACACCGACTTTAGAT AGTTTGGCACGTGATTTAACAGTTATTGCTCGGGAAGATAATTTGGATCCGGTTATTGGCCGTTCTAAAG AAATCCAACGTGTGATTGAAGTGCTTAGTCGTCGTACGAAGAATAACCCAGTACTTATTGGAGAACCTGG TGTTGGTAAAACAGCGATTGCAGAAGGACTAGCGCAACAAATTGTTCGTAATGAAGTGCCTGAGACTTTA CGTGGAAAACGTGTAATGACACTGGATATGGGGACTGTTGTGGCAGGGACAAAATATCGTGGTGAATTTG AAGACCGTTTGAAAAAAGTAATGGATGAGATTCGTCAAGCCGGCAATGTTATTCTATTTATTGATGAATT GCATACCTTAATTGGTGCTGGTGGAGCGGAAGGTGCGATTGATGCCTCGAATATCTTGAAGCCGCCTCTA GCTCGTGGTGAGTTGCAATGTATTGGTGCAACAACACTGGATGAGTACCGTAAATATATTGAAAAAGATG CTGCACTTGAGAGACGTTTCCAACCGATTAAAGTAGATGAGCCAACTGTAGAAGAATCCATTCAAATTTT ACATGGGTTGCGTGATCGTTATGAGGCGCATCACCGTGTTGCGATTACTGATGAAGCGCTTGAGGCTGCT GTTCGTCTATCTGATCGGTACATTTCAGACCGTTTCTTACCGGATAAAGCGATTGATGTTATTGATGAAT CTGGTTCTAAAGTACGTTTGAAATCTTTTACAACGCCAAAAAATGTAAAAGAAATGGAAAACAATTTATC CGATTTGAAAAAAGAAAAAGATGCGGCTGTTCAAGGGCAAGAATTTGAAAAAGCAGCGTCATTACGCGAT AAAGAACAAAAACTTAAAAAATCATTAGAAGAAACAAAAGCGAATTGGCAAGAAAAGCAAGGGCTTGACC ATAGTGAAGTAACAGAAGAGATTGTTGCTGAAGTTGTTGCAAGTTGGACTGGGATTCCAGTTGCAAAACT TGCGGAAACAGAGACAAATAAACTTTTAAATATGGAGAAACTTTTACATGAACGCGTGATTGGGCAAGAT GCTGCGGTGAAAGCTGTTTCGCTAGCTGTACGTAGAGCTCGTGCTGGACTTAAAGATCCTAAGCGTCCAA TTGGTTCCTTTATTTTCCTTGGACCTACTGGTGTTGGGAAAACAGAACTTGCTCGCGCGCTTGCTGAGTC TATGTTTGGCGATGAGGATTCGATGATTCGAATTGACATGTCTGAGTACATGGAGAAATTCTCGACTGCT CGTTTAGTTGGGGCTCCTCCAGGTTATGTAGGCTATGAAGAAGGTGGGCAACTGACAGAAAAAGTTCGTC AAAAACCTTATTCAGTAGTTCTTTTAGATGAAATTGAAAAAGCGCATCCGGATGTATTTAATATGTTGCT ACAAGTGCTTGACGATGGTCGTTTGACTGATTCTAAAGGACGGGTGGTTGATTTTAGAAATACGGTCATC ATTATGACTTCCAATATTGGGGCTCAAGAAATGAAACAAGATAAATCAATGGGCTTTAATGTTATTGATC CGCTTAAAGACCATAAAGCTATGGAGCACCGTGTTTTACAAGATTTAAAACAGGCGTTCCGGCCAGAGTT TATCAACCGAATTGATGAAACAATTGTATTCCATTCGCTACAAGAAAAAGAATTGAAACAAATTGTTACT TTGCTGACTGCTCAATTAACAAAACGATTAGCCGAACGCGATATTCATGTGAAATTAACTGAAGGTGCGA AATCCAAAATTGCTAAAGACGGATACGATCCAGAATACGGAGCCCGTCCTTTGAAACGAGCTATTCAAAA AGAAGTGGAAGATATGCTTTCTGAAGAATTACTTCGTGGTAACATTAAAGTAGGCGATTACGTGGAAATT GGTGTAAAAGATGGCAAGTTAGAGGTTAGAAAAAAAGACGCACCAAAAAAGAAAACAACCGCAAAAAAAG TAAAAACTAAATAACAAACACGCCTCCCTTAATCAATTTTGAAGGGAG
Protein Sequence	>gi\|226222861\|ref\|YP_002756968.1\| endopeptidase Clp ATP-binding chain C [Listeria monocytogenes serotype 4b str. CLIP 80459] MMFGRFTQRAQKVLALSQEEAMRLNHSNLGTEHILLGLVREGEGIAAKALYELGISSEKVQQEVEGLIGHGEKAVTTIQYTPRAKKVIELSMDEARKLGHTYVGTEHILLGLIREGEGVAARVLSNLGISLNKARQQVLQLLGGGDATGAGRQTNTQATPTLDSLARDLTVIAREDNLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIVRNEVPETLRGKRVMTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNVILFIDELHTLIGAGGAEGAIDASNILKPPLARGELQCIGATTLDEYRKYIEKDAALERRFQPIKVDEPTVEESIQILHGLRDRYEAHHRVAITDEALEAAVRLSDRYISDRFLPDKAIDVIDESGSKVRLKSFTTPKNVKEMENNLSDLKKEKDAAVQGQEFEKAASLRDKEQKLKKSLEETKANWQEKQGLDHSEVTEEIVAEVVASWTGIPVAKLAETETNKLLNMEKLLHERVIGQDAAVKAVSLAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAESMFGDEDSMIRIDMSEYMEKFSTARLVGAPPGYVGYEEGGQLTEKVRQKPYSVVLLDEIEKAHPDVFNMLLQVLDDGRLTDSKGRVVDFRNTVIIMTSNIGAQEMKQDKSMGFNVIDPLKDHKAMEHRVLQDLKQAFRPEFINRIDETIVFHSLQEKELKQIVTLLTAQLTKRLAERDIHVKLTEGAKSKIAKDGYDPEYGARPLKRAIQKEVEDMLSEELLRGNIKVGDYVEIGVKDGKLEVRKKDAPKKKTTAKKVKTK
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: mutant strain showed a restricted capacity to grow in bone-marrow-derived macrophages, and an attenuated virulence in mice (Rouquette et al., 1996).
COG	COG0542O, under O: Posttranslational modification, protein turnover, chaperones
References	*Rouquette et al., 1996:* Rouquette C, Ripio MT, Pellegrini E, Bolla JM, Tascon RI, VÃ¡zquez-Boland JA, Berche P. Identification of a ClpC ATPase required for stress tolerance and in vivo survival of Listeria monocytogenes. Molecular microbiology. 1996; 21(5); 977-987. [PubMed: 8885268].


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clpC from Listeria monocytogenes serotype 4b str. CLIP 80459