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tlyA

Victor ID 3806
Gene Name tlyA
Sequence Strain (Species/Organism) Helicobacter
NCBI Gene ID 8208922
NCBI Protein GI 254779055
Locus Tag HELPY_0367
Protein Accession YP_003057160.1
Other Database IDs UniProtKB-ID: C7BYV0_HELPB
UniRef100: UniRef100_C7BYV0
UniRef90: UniRef90_B2USJ4
UniRef50: UniRef50_B2USJ4
UniParc: UPI0001AF8607
EMBL: FM991728
EMBL-CDS: CAX28910.1
RefSeq_NT: NC_012973.1
GenomeReviews: FM991728_GR
KEGG: hpb:HELPY_0367
ProtClustDB: CLSK2517382
Taxonomy ID 592205
Gene Starting Position 364230
Gene Ending Position 364937
Gene Strand (Orientation) -
Protein Name Pore-forming cytolysin
DNA Sequence 
>gi|254778738:364230-364937 Helicobacter pylori B38, complete genome
CTCAGGCTCGCTTGAAATGGATAAAAAATTCAACATTCCCGTTTTTCCCTTTCACTAAGCTTTCTTGGAT
CGTTAAGATTTGAAAATCCTTTGTTTTTAAATGGTTTTTAAAGTTTTCTAAAGCGTTTAAAATGGCTTTT
TTATCCATTACCACCCCCTTTTTATTGCGTTTTGTGGCTCTGCCCACTTCAAATTGCGGTTTGAAAAGCG
CTAAAAATTCACCGCTTAAAGGCACAATCGCTTCTAAAATACAATATAAAGAAATAAAGCTCACATCACA
AAGCACTAAATCAATTTTTTCTGGCGTTTTAAACCCTCTAATATCGCATTCTTCGTAACATTCTATGCGC
TGGTCGTTTTTCAAACCCTCATCTAATTGCATTTTCCCTACATCCACGCAAAGCACCTTTTTAGCCCCTT
TTAAAAGAGCCACTTGACTAAAGCCCCCCTTACTCGCTCCCACATCTAAAACAACCTTTTCTTTAAAATC
TATAAAGTGATTTTCTAAAAAAGCCCCTAATTTTTCCCCAGCCCTGCTAACGAGTAAATTTGGAGCGATG
AGTTCAATTTGATCACCCTCTTTAACGATAAAAGAGGGTTTAGAAACCACCATTTTATTGACTAAAACCT
GATTTTTTAAAACCAACGCTTTAGCTTTTTCTCTGCTATTTGCTAAATGCTGGTTGAATAAGGCGTAATC
TAAGCGCA
Protein Sequence 
>gi|254779055|ref|YP_003057160.1| Pore-forming cytolysin [Helicobacter pylori B38] MRLDYALFNQHLANSREKAKALVLKNQVLVNKMVVSKPSFIVKEGDQIELIAPNLLVSRAGEKLGAFLENHFIDFKEKVVLDVGASKGGFSQVALLKGAKKVLCVDVGKMQLDEGLKNDQRIECYEECDIRGFKTPEKIDLVLCDVSFISLYCILEAIVPLSGEFLALFKPQFEVGRATKRNKKGVVMDKKAILNALENFKNHLKTKDFQILTIQESLVKGKNGNVEFFIHFKRA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutated strain showed a reduction in adherence ability (Zhang et al., 2002).
COG COG1189J, under J: Translation, ribosomal structure and biogenesis
References
Zhang et al., 2002: Zhang ZW, Dorrell N, Wren BW, Farthingt MJ. Helicobacter pylori adherence to gastric epithelial cells: a role for non-adhesin virulence genes. Journal of medical microbiology. 2002; 51(6); 495-502. [PubMed: 12018657].