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hlyC from Escherichia coli Vir68

Victor ID 3793
Gene Name hlyC from Escherichia coli Vir68
Sequence Strain (Species/Organism) Escherichia coli Vir68
NCBI Gene ID 8164736
NCBI Protein GI 253801086
Locus Tag pVir_111
Protein Accession YP_003034087.1
Other Database IDs UniProtKB-ID: C5ZZQ6_ECOLX
UniRef100: UniRef100_C5ZZQ6
UniRef90: UniRef90_P09985
UniRef50: UniRef50_P09985
UniParc: UPI0001AE5063
EMBL: CP001162
EMBL-CDS: ACT33570.1
RefSeq_NT: NC_012944.1
Taxonomy ID 563770
Plasmid No pVir68
Gene Starting Position 123584
Gene Ending Position 123916
Gene Strand (Orientation) -
Protein Name hemolysin activating protein HlyC
DNA Sequence 
>gi|253800975:123584-123916 Escherichia coli Vir68 plasmid pVir68, complete sequence
ATCAGGGGATTTTTTTTCGCATATATTTGTACAGGGCACCGTTATCCCCGAAAGGAGCAATCCAGTCAAT
GAACCATTTACGATCACCTGAAGTCCAGTCTTCTGCGACTAATGAGGTAACATCATTAAGATATTTAATT
TCATTTTCTAAACTTAAATTAGCCCAACTACAATATGCAACAGGGTAATTATCCTGGGTTAATAAAGCAT
ATTGGTTAGCCCGTATTGCAGGTAATACATTTATTGCAAACAAAGAGACTGGCCAGTTTCTGTGTAGTGG
GGAACTGGCCCAGAGCCAAGATACATGCCCAAGAACCTCTAATGGATTGTTCA
Protein Sequence 
>gi|253801086|ref|YP_003034087.1| hemolysin activating protein HlyC [Escherichia coli Vir68] MNNPLEVLGHVSWLWASSPLHRNWPVSLFAINVLPAIRANQYALLTQDNYPVAYCSWANLSLENEIKYLNDVTSLVAEDWTSGDRKWFIDWIAPFGDNGALYKYMRKKIP
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hlyC is required for the acylation and therefore activation of the toxin hemolysin which has the ability to lyse several different types of cells (Stanley et al., 1996).
References
Stanley et al., 1996: Stanley P, Koronakis V, Hardie K, Hughes C. Independent interaction of the acyltransferase HlyC with two maturation domains of the Escherichia coli toxin HlyA. Molecular microbiology. 1996; 20(4); 813-822. [PubMed: 8793877].