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espP from Escherichia coli O157:H7 str. TW14359

Victor ID 3791
Gene Name espP from Escherichia coli O157:H7 str. TW14359
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. TW14359
NCBI Gene ID 8206968
NCBI Protein GI 254667544
Locus Tag ECSP_6096
Protein Accession YP_003082230.1
Other Database IDs UniProtKB-ID: C6V3L8_ECO5T
UniRef100: UniRef100_Q7BSW5
UniRef90: UniRef90_O32591
UniRef50: UniRef50_O32591
UniParc: UPI00000B5B8A
EMBL: CP001369
EMBL-CDS: ACT75256.1
RefSeq_NT: NC_013010.1
EnsemblGenome: EBESCG00000167728.
EnsemblGenome_TRS: EBESCT00000169028
EnsemblGenome_PRO: EBESCP00000158339
GenomeReviews: CP001369_GR
KEGG: etw:ECSP_6096
ProtClustDB: CLSK2517096
Taxonomy ID 544404
Plasmid No pO157
Gene Starting Position 80366
Gene Ending Position 84268
Gene Strand (Orientation) +
Protein Name putative exoprotein-precursor
DNA Sequence 
>gi|254667448:80366-84268 Escherichia coli O157:H7 str. TW14359 plasmid pO157, complete sequence
TATGAATAAAATATACTCTCTTAAATACAGCCATATTACAGGAGGGTTAATCGCTGTTTCTGAATTATCC
GGCAGAGTATCATCAAGAGCAACTGGTAAGAAAAAACACAAACGCATACTTGCATTATGTTTTTTAGGCT
TATTACAATCCTCATATTCTTTTGCGTCACAGATGGATATTTCAAATTTCTACATCCGTGACTATATGGA
TTTTGCACAGAACAAGGGCATATTTCAGGCTGGCGCAACAAATATTGAAATAGTGAAGAAAGATGGCTCC
ACCCTGAAACTACCGGAAGTACCATTTCCTGACTTCTCACCGGTTGCAAACAAAGGGTCAACCACATCTA
TTGGTGGTGCATACAGTATCACAGCCACACACAATACGAAAAACCACCACTCAGTTGCGACGCAAAACTG
GGGGAACAGCACGTACAAACAAACTGACTGGAATACTTCACATCCTGATTTTGCAGTATCCCGACTTGAC
AAGTTTGTTGTTGAGACCCGAGGTGCGACTGAAGGCGCAGATATTTCGTTATCAAAACAGCAGGCACTTG
AACGTTACGGGGTTAATTATAAAGGAGAAAAGAAACTTATCGCATTCAGAGCCGGCTCTGGTGTGGTATC
CGTTAAAAAAAATGGACGCATAACTCCATTTAATGAGGTTTCTTATAAGCCAGAAATGTTAAATGGCTCT
TTCGTTCACATTGATGACTGGAGTGGATGGCTGATATTAACCAACAACCAGTTTGATGAGTTTAATAACA
TTGCCTCTCAGGGTGACAGCGGTTCAGCACTGTTCGTCTATGATAACCAAAAGAAAAAGTGGGTTGTCGC
TGGAACTGTCTGGGGGATTTATAATTACGCCAATGGCAAAAACCACGCAGCATACAGTAAATGGAACCAG
ACAACCATTGACAACCTGAAGAACAAGTATTCTTACAACGTGGATATGTCAGGGGCTCAGGTTGCAACCA
TTGAAAATGGAAAACTGACAGGCACTGGCTCAGACACCACCGATATAAAAAATAAGGACTTAATATTTAC
TGGCGGTGGAGATATCCTCCTGAAATCCTCTTTTGATAATGGTGCTGGCGGTCTTGTCTTTAATGATAAA
AAGACCTATCGAGTAAACGGGGATGATTTCACCTTTAAAGGTGCCGGTGTTGATACAAGAAACGGCAGCA
CCGTTGAGTGGAATATCCGGTATGATAATAAAGACAACCTTCACAAAATTGGTGATGGCACATTAGATGT
CCGAAAAACCCAGAACACCAACCTGAAAACAGGTGAGGGTCTTGTCATTCTTGGAGCTGAAAAAACATTC
AATAATATCTACATAACCAGTGGTGATGGAACTGTCCGACTGAATGCAGAAAATGCACTGTCTGGCGGTG
AATACAACGGTATTTTCTTTGCGAAAAATGGCGGAACTCTTGACCTGAACGGATATAATCAGTCTTTCAA
TAAAATTGCTGCAACTGATTCAGGTGCTGTAATAACCAATACGTCAACCAAAAAATCCATTTTATCCCTG
AATAATACTGCTGACTATATCTATCACGGCAACATAAACGGGAATCTGGACGTACTTCAGCATCATGAGA
CGAAAAAAGAGAACCGTCGTCTTATTCTTGATGGGGGCGTGGACACAACAAATGATATAAGCCTGCGTAA
TACACAACTGTCCATGCAGGGACATGCCACTGAACATGCCATTTATCGGGATGGAGCTTTCTCTTGTTCA
CTACCAGCTCCTATGCGCTTTTTGTGTGGCAGTGATTATGTTGCAGGAATGCAAAATACAGAAGCTGATG
CTGTAAAACAAAACGGAAATGCCTATAAAACCAACAATGCTGTCTCTGATTTATCGCAGCCAGACTGGGA
AACCGGAACATTCAGATTTGGAACGCTACATCTTGAAAATTCCGATTTTTCTGTTGGTCGTAATGCAAAT
GTAATCGGGGACATTCAGGCCAGTAAATCAAACATTACTATTGGTGACACTACAGCATATATTGATTTGC
ATGCTGGTAAAAATATTACCGGTGATGGTTTTGGCTTCCGCCAGAATATTGTGCGTGGAAACTCACAAGG
AGAAACGCTGTTTACAGGAGGGATCACAGCAGAAGACAGCACTATCGTTATTAAAGATAAAGCAAAAGCA
TTATTTTCAAATTATGTATACCTGCTGAACACAAAAGCAACCATAGAGAACGGTGCTGATGTGACAACTC
AAAGTGGTATGTTCTCCACGAGCGATATCAGCATCTCTGGTAATCTGTCCATGACAGGCAATCCCGACAA
AGACAATAAATTCGAGCCCTCAATATATCTGAATGATGCTTCTTATCTACTGACTGACGACTCCGCCAGA
CTCGTTGCCAAAAATAAAGCATCTGTGGTGGGAGATATACACTCCACTAAAAGTGCATCCATCATGTTTG
GTCATGATGAAAGCGACCTCTCGCAGTTGTCTGACAGAACCTCAAAAGGGCTTGCACTTGGTCTTTTAGG
TGGCTTTGATGTCTCATATCGCGGTTCAGTCAATGCCCCGTCAGCATCTGCCACTATGAACAACACCTGG
TGGCAACTAACCGGAGATTCTGCGCTGAAAACACTGAAAAGTACAAACAGCATGGTCTATTTCACTGACA
GCGCAAACAATAAGAAATTCCATACGCTGACGGTCGATGAGCTGGCAACCAGCAACAGCGCCTATGCGAT
GCGTACAAACCTTTCTGAATCAGACAAACTGGAGGTCAAAAAACACTTGTCTGGTGAGAACAATATTTTA
CTCGTTGATTTCCTTCAGAAACCAACGCCTGAAAAACAACTGAATATTGAACTGGTAAGCGCGCCAAAAG
ACACCAATGAAAATGTCTTTAAAGCCAGTAAACAAACCATTGGTTTCAGTGATGTAACGCCGGTCATTAC
AACCAGGGAAACCGATGACAAAATAACATGGTCACTGACAGGCTATAACACGGTAGCAAACAAGGAAGCA
ACCCGGAATGCCGCCGCCCTGTTCTCTGTTGACTATAAAGCGTTTCTGAACGAGGTCAACAACCTGAACA
AACGTATGGGTGACCTGCGTGATATCAACGGCGAAGCCGGTGCATGGGCACGCATCATGAGCGGTACCGG
CTCTGCCAGTGGTGGTTTCAGTGACAACTACACGCACGTTCAGGTCGGGGTCGACAAAAAACACGAGCTG
GACGGACTGGATTTGTTTACCGGTTTCACTGTCACACACACTGACAGCAGTGCCTCCGCCGATGTTTTCA
GTGGTAAAACGAAGTCTGTGGGGGCTGGCCTGTATGCTTCCGCCATGTTTGATTCCGGTGCCTATATCGA
CCTGATTGGCAAGTATGTTCACCATGATAATGAGTACACTGCAACCTTTGCCGGACTCGGAACCCGTGAT
TACAGCACGCATTCATGGTATGCCGGTGCAGAAGCGGGCTACCGCTATCATGTCACTGAGGATGCCTGGA
TTGAGCCACAGGCTGAGCTGGTTTACGGTTCTGTATCCGGTAAACAGTTTGCATGGAAGGACCAGGGAAT
GCATCTGTCCATGAAGGACAAGGACTACAATCCGCTGATTGGCCGAACGGGTGTGGATGTGGGTAAATCC
TTCTCTGGTAAGGACTGGAAAGTGACAGCCCGTGCCGGTCTGGGCTACCAGTTCGACCTGCTGGCTAACG
GCGAAACCGTATTGCGGGATGCATCTGGTGAAAAACGCATCAAAGGTGAAAAGGACAGCCGTATGCTGAT
GTCCGTTGGCCTGAATGCAGAAATCAGGGATAACGTCCGCTTTGGACTGGAGTTTGAGAAATCCGCCTTT
GGTAAGTACAACGTTGATAATGCTGTCAACGCTAATTTCCGTTACTCGTTCTG
Protein Sequence 
>gi|254667544|ref|YP_003082230.1| putative exoprotein-precursor [Escherichia coli O157:H7 str. TW14359] MNKIYSLKYSHITGGLIAVSELSGRVSSRATGKKKHKRILALCFLGLLQSSYSFASQMDISNFYIRDYMDFAQNKGIFQAGATNIEIVKKDGSTLKLPEVPFPDFSPVANKGSTTSIGGAYSITATHNTKNHHSVATQNWGNSTYKQTDWNTSHPDFAVSRLDKFVVETRGATEGADISLSKQQALERYGVNYKGEKKLIAFRAGSGVVSVKKNGRITPFNEVSYKPEMLNGSFVHIDDWSGWLILTNNQFDEFNNIASQGDSGSALFVYDNQKKKWVVAGTVWGIYNYANGKNHAAYSKWNQTTIDNLKNKYSYNVDMSGAQVATIENGKLTGTGSDTTDIKNKDLIFTGGGDILLKSSFDNGAGGLVFNDKKTYRVNGDDFTFKGAGVDTRNGSTVEWNIRYDNKDNLHKIGDGTLDVRKTQNTNLKTGEGLVILGAEKTFNNIYITSGDGTVRLNAENALSGGEYNGIFFAKNGGTLDLNGYNQSFNKIAATDSGAVITNTSTKKSILSLNNTADYIYHGNINGNLDVLQHHETKKENRRLILDGGVDTTNDISLRNTQLSMQGHATEHAIYRDGAFSCSLPAPMRFLCGSDYVAGMQNTEADAVKQNGNAYKTNNAVSDLSQPDWETGTFRFGTLHLENSDFSVGRNANVIGDIQASKSNITIGDTTAYIDLHAGKNITGDGFGFRQNIVRGNSQGETLFTGGITAEDSTIVIKDKAKALFSNYVYLLNTKATIENGADVTTQSGMFSTSDISISGNLSMTGNPDKDNKFEPSIYLNDASYLLTDDSARLVAKNKASVVGDIHSTKSASIMFGHDESDLSQLSDRTSKGLALGLLGGFDVSYRGSVNAPSASATMNNTWWQLTGDSALKTLKSTNSMVYFTDSANNKKFHTLTVDELATSNSAYAMRTNLSESDKLEVKKHLSGENNILLVDFLQKPTPEKQLNIELVSAPKDTNENVFKASKQTIGFSDVTPVITTRETDDKITWSLTGYNTVANKEATRNAAALFSVDYKAFLNEVNNLNKRMGDLRDINGEAGAWARIMSGTGSASGGFSDNYTHVQVGVDKKHELDGLDLFTGFTVTHTDSSASADVFSGKTKSVGAGLYASAMFDSGAYIDLIGKYVHHDNEYTATFAGLGTRDYSTHSWYAGAEAGYRYHVTEDAWIEPQAELVYGSVSGKQFAWKDQGMHLSMKDKDYNPLIGRTGVDVGKSFSGKDWKVTARAGLGYQFDLLANGETVLRDASGEKRIKGEKDSRMLMSVGLNAEIRDNVRFGLEFEKSAFGKYNVDNAVNANFRYSF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: espP mutant is attenuated in calves (Dziva et al., 2007).
COG COG4625S, under S: Function unknown
References
Dziva et al., 2007: Dziva F, Mahajan A, Cameron P, Currie C, McKendrick IJ, Wallis TS, Smith DG, Stevens MP. EspP, a Type V-secreted serine protease of enterohaemorrhagic Escherichia coli O157:H7, influences intestinal colonization of calves and adherence to bovine primary intestinal epithelial cells. FEMS microbiology letters. 2007; 271(2); 258-264. [PubMed: 17451446].