Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

hlyA from Escherichia coli O157:H7 str. TW14359

Victor ID 3790
Gene Name hlyA from Escherichia coli O157:H7 str. TW14359
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. TW14359
NCBI Gene ID 8206890
NCBI Protein GI 254667466
Locus Tag ECSP_6018
Protein Accession YP_003082152.1
Other Database IDs UniProtKB-ID: C6V3E0_ECO5T
UniRef100: UniRef100_A8QWI1
UniRef90: UniRef90_A1EAA3
UniRef50: UniRef50_P55129
UniParc: UPI00015E1A28
EMBL: CP001369
EMBL-CDS: ACT75178.1
RefSeq_NT: NC_013010.1
EnsemblGenome: EBESCG00000166578.
EnsemblGenome_TRS: EBESCT00000165130
EnsemblGenome_PRO: EBESCP00000159423
GenomeReviews: CP001369_GR
KEGG: etw:ECSP_6018
ProtClustDB: CLSK862058
Taxonomy ID 544404
Plasmid No pO157
Gene Starting Position 16794
Gene Ending Position 19790
Gene Strand (Orientation) +
Protein Name hemolysin toxin protein
DNA Sequence 
>gi|254667448:16794-19790 Escherichia coli O157:H7 str. TW14359 plasmid pO157, complete sequence
TATGACAGTAAATAAAATAAAGAACATTTTCAATAATGCGACATTGACTACAAAATCAGCATTTAATACA
GCATCATCAAGCGTACGTTCCGCTGGAAAAAAACTCATATTATTAATACCTGATAATTATGAAGCTCAGG
GCGTGGGTATTAATGAGTTGGTCAAAGCTGCTGATGAGCTTGGAATAGAAATACACCGTACTGAACGAGA
TGATACAGCGATTGCAAACCAGTTTTTTGGTGCAGCAGAAAAAGTTGTAGGATTAACTGAACGTGGTGTT
GCAATATTCGCACCACAACTTGACAAACTTCTGCAGAAGTATCAGAAAGTTGGGAGTAAAATAGGAGGAA
CCGCTGAAAATGTAGGTAATAATCTGGGAAAAGCCGGAACAGTTCTCTCAGCACTACAGAATTTTACGGG
GATTGCTTTATCAGGCATGGCTCTTGATGAATTGCTGAGAAAACAACGGGCAGGAGAGGATATAAGTCAG
AATGATATTGCCAAAAGTAGTATTGAACTTATTAATCAGCTTGTAGATACAGTATCAAGTATAAACAGTA
CCGTTGATTCATTTTCTGAGCAGCTTAACCAGCTTGGCTCATTTTTATCCAGTAAACCTCGATTAAGTTC
TGTTGGTGGGAAATTACAAAATTTACCAGACCTGGGCCCCCTGGGGGATGGGCTGGATGTTGTCTCCGGA
ATTCTTTCTGCTGTATCAGCAAGCTTTATTCTGGGAAACAGTGACGCACATACAGGAACAAAAGCTGCAG
CGGGTATCGAACTGACAACTCAGGTTCTTGGAAATGTTGGTAAAGCTGTTTCGCAATATATTCTGGCTCA
GAGAATGGCACAGGGGTTATCGACAACAGCTGCAAGTGCGGGTCTGATCACATCGGCTGTTATGCTGGCT
ATCAGTCCTCTTTCTTTCCTGGCTGCTGCAGATAAATTTGAGCGAGCTAAGCAGCTTGAATCATATTCTG
AACGATTTAAAAAATTGAATTATGAAGGGGATGCTTTACTCGCAGCCTTTCATAAAGAAACCGGAGCTAT
AGATGCAGCCCTGACAACAATAAATACTGTCCTGAGTTCTGTATCTGCGGGAGTTAGTGCAGCCTCCAGT
GCATCCCTCATAGGGGCCCCGATAAGCATGCTGGTGAGTGCATTAACCGGTACGATATCTGGCATTCTGG
AAGCATCAAAACAGGCTATGTTTGAGCACGTTGCAGAGAAATTCGCTGCTCGGATCAATGAATGGGAAAA
GGAGCATGGCAAAAATTATTTTGAGAATGGATATGACGCAAGACATGCTGCGTTTTTAGAAGACTCTCTG
TCTTTGCTTGCTGATTTTTCTCGTCAGCATGCAGTAGAAAGAGCAGTCGCAATAACCCAGCAACATTGGG
ATGAGAAGATCGGTGAACTTGCAGGCATAACCCGTAATGCTGATCGCAGTCAGAGTGGTAAGGCATATAT
TAATTATCTGGAAAATGGAGGGCTTTTAGAGGCTCAACCGAAGGAGTTTACACAACAAGTGTTTGATCCT
CAAAAAGGGACCATAGACCTTTCAACAGGTAATGTATCAAGTGTTTTGACATTTATAACACCAACATTTA
CCCCAGGAGAAGAAGTTAGAGAAAGAAAACAGAGTGGTAAATATGAATATATGACATCTCTTATTGTAAA
TGGTAAGGATACATGGTCTGTAAAAGGCATAAAAAATCATAAAGGTGTATATGATTATTCAAAATTGATT
CAGTTTGTTGAAAAGAATAACAAACACTATCAGGCGAGAATAATTTCTGAGCTCGGAGATAAAGACGATG
TGGTTTATTCTGGAGCAGGCTCATCAGAAGTATTTGCTGGTGAAGGTTATGATACCGTATCTTATAATAA
GACGGATGTTGGTAAACTAACAATTGATGCAACAGGAGCATCAAAACCTGGTGAGTATATAGTTTCAAAA
AATATGTATGGTGACGTGAAGGTATTGCAGGAAGTCGTTAAGGAACAGGAGGTGTCAGTAGGGAAGCGAA
CAGAGAAAATACAATATCGTGATTTTGAATTCAGAACCGGTGGAATTCCTTATGATGTAATAGATAATCT
TCATTCTGTTGAAGAGCTCATTGGCGGAAAACATGATGATGAATTCAAAGGCGGTAAGTTTAATGATATA
TTCCATGGCGCAGATGGGAACGATTATATCGAAGGTAATTATGGTAATGATCGACTATACGGCGATGATG
GGGATGATTATATATCCGGAGGACAGGGAGACGACCAGTTATTTGGTGGTAGTGGAAACGATAAATTGAG
TGGAGGGGATGGTAATAATTATCTGACAGGAGGAAGCGGTAATGATGAGCTTCAGGCACACGGAGCTTAT
AATATTCTGTCAGGTGGTACTGGTGATGATAAACTTTATGGTGGTGGTGGTATTGATCTTCTGGATGGAG
GGGAAGGTAATGACTATCTGAATGGTGGTTTTGGTAATGATATTTATGTTTATGGGCAAAACTATGGTCA
TCATACAATTGCAGATGAAGGAGGTAAAGGAGATCGTTTGCACTTATCTGATATTAGCTTTGATGATATC
GCATTTAAGAGAGTTGGAAATGATCTTATCATGAATAAAGCCATTAATGGTGTACTTTCATTTAATGAGT
CAAATGATGTCAATGGGATAACATTTAAAAACTGGTTTGCGAAAGATGCCTCAGGAGCAGATAATCATCT
TGTTGAGGTTATAACAGATAAAGATGGTCGAGAGATAAAAGTTGATAAGATACCTCATAATAATAATGAA
CGGTCAGGTTATATAAAAGCCAGTAATATAGCATCTGAAAAAAACATGGTTAATATCACCAGTGTTGCCA
ATGATATTAATAAGATTATTTCTTCAGTTTCAGGGTTCGATTCAGGTGATGAACGATTAGCATCTTTATA
TAATTTATCCTTACATCAAAACAACACACACTCAACAACTTTAACGACAACTGTCTG
Protein Sequence 
>gi|254667466|ref|YP_003082152.1| hemolysin toxin protein [Escherichia coli O157:H7 str. TW14359] MTVNKIKNIFNNATLTTKSAFNTASSSVRSAGKKLILLIPDNYEAQGVGINELVKAADELGIEIHRTERDDTAIANQFFGAAEKVVGLTERGVAIFAPQLDKLLQKYQKVGSKIGGTAENVGNNLGKAGTVLSALQNFTGIALSGMALDELLRKQRAGEDISQNDIAKSSIELINQLVDTVSSINSTVDSFSEQLNQLGSFLSSKPRLSSVGGKLQNLPDLGPLGDGLDVVSGILSAVSASFILGNSDAHTGTKAAAGIELTTQVLGNVGKAVSQYILAQRMAQGLSTTAASAGLITSAVMLAISPLSFLAAADKFERAKQLESYSERFKKLNYEGDALLAAFHKETGAIDAALTTINTVLSSVSAGVSAASSASLIGAPISMLVSALTGTISGILEASKQAMFEHVAEKFAARINEWEKEHGKNYFENGYDARHAAFLEDSLSLLADFSRQHAVERAVAITQQHWDEKIGELAGITRNADRSQSGKAYINYLENGGLLEAQPKEFTQQVFDPQKGTIDLSTGNVSSVLTFITPTFTPGEEVRERKQSGKYEYMTSLIVNGKDTWSVKGIKNHKGVYDYSKLIQFVEKNNKHYQARIISELGDKDDVVYSGAGSSEVFAGEGYDTVSYNKTDVGKLTIDATGASKPGEYIVSKNMYGDVKVLQEVVKEQEVSVGKRTEKIQYRDFEFRTGGIPYDVIDNLHSVEELIGGKHDDEFKGGKFNDIFHGADGNDYIEGNYGNDRLYGDDGDDYISGGQGDDQLFGGSGNDKLSGGDGNNYLTGGSGNDELQAHGAYNILSGGTGDDKLYGGGGIDLLDGGEGNDYLNGGFGNDIYVYGQNYGHHTIADEGGKGDRLHLSDISFDDIAFKRVGNDLIMNKAINGVLSFNESNDVNGITFKNWFAKDASGADNHLVEVITDKDGREIKVDKIPHNNNERSGYIKASNIASEKNMVNITSVANDINKIISSVSGFDSGDERLASLYNLSLHQNNTHSTTLTTTV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in zebra fish (Wiles et al., 2009).
References
Wiles et al., 2009: Wiles TJ, Bower JM, Redd MJ, Mulvey MA. Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli. PLoS pathogens. 2009; 5(12); e1000697. [PubMed: 20019794].