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hlyC from Escherichia coli O157:H7 str. TW14359

Victor ID 3789
Gene Name hlyC from Escherichia coli O157:H7 str. TW14359
Sequence Strain (Species/Organism) Escherichia coli O157:H7 str. TW14359
NCBI Gene ID 8206889
NCBI Protein GI 254667465
Locus Tag ECSP_6017
Protein Accession YP_003082151.1
Other Database IDs UniProtKB-ID: C6V3D9_ECO5T
UniRef100: UniRef100_Q5K5Z5
UniRef90: UniRef90_Q5K5Z5
UniRef50: UniRef50_P09985
UniParc: UPI00000B3039
EMBL: CP001369
EMBL-CDS: ACT75177.1
RefSeq_NT: NC_013010.1
EnsemblGenome: EBESCG00000168555.
EnsemblGenome_TRS: EBESCT00000166430
EnsemblGenome_PRO: EBESCP00000157356
GenomeReviews: CP001369_GR
KEGG: etw:ECSP_6017
ProtClustDB: CLSK862057
Taxonomy ID 544404
Plasmid No pO157
Gene Starting Position 16277
Gene Ending Position 16792
Gene Strand (Orientation) +
Protein Name hemolysin transport protein
DNA Sequence 
>gi|254667448:16277-16792 Escherichia coli O157:H7 str. TW14359 plasmid pO157, complete sequence
TATGAAATCTAATGCTTTTGACGTCATGGGGAAGGTTGCATGGCTATGGGCCTGTTCTCCTCTGCATAAA
AAATGGCCATTATCTGTTTTTGCTATTAATGTCATACCTGCTATTCAGACAAATCAATTTGCTCTCTTAA
TAAAGGATGAGCTTCCTGTAGCTTTTTGTAGCTGGGCCAGTTTAGATCTGGAATGTGAGGTAAAATATAT
AAATGATGTAACATCTTTGTATGCAAAAGACTGGATGTCGGGAGAAAGAAAGTGGTTTATTGACTGGATA
GCTCCATTTGGACACAACATGGAGTTATATAAATACATGAGGAAAAAGTATCCTTATGAGTTATTCAGAG
CAATAAGGTTAGATGAGAGCAGTAAAACAGGAAAAATAGCTGAATTTCATGGAGGGGGGATAGATAAAAA
ACTGGCATCAAAAATATTCAGGCAATACCATCATGAACTTATGTCTGAAGTAAAAAACAGACAAGATTTT
AATTTTAATATTGAGAAAGAAAACTA
Protein Sequence 
>gi|254667465|ref|YP_003082151.1| hemolysin transport protein [Escherichia coli O157:H7 str. TW14359] MKSNAFDVMGKVAWLWACSPLHKKWPLSVFAINVIPAIQTNQFALLIKDELPVAFCSWASLDLECEVKYINDVTSLYAKDWMSGERKWFIDWIAPFGHNMELYKYMRKKYPYELFRAIRLDESSKTGKIAEFHGGGIDKKLASKIFRQYHHELMSEVKNRQDFNFNIEKEN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hlyC is required for the acylation and therefore activation of the toxin hemolysin which has the ability to lyse several different types of cells (Stanley et al., 1996).
COG COG2994O, under O: Posttranslational modification, protein turnover, chaperones
References
Stanley et al., 1996: Stanley P, Koronakis V, Hardie K, Hughes C. Independent interaction of the acyltransferase HlyC with two maturation domains of the Escherichia coli toxin HlyA. Molecular microbiology. 1996; 20(4); 813-822. [PubMed: 8793877].