Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

hlyC from Escherichia coli O26:H11 str. 11368

Victor ID 3785
Gene Name hlyC from Escherichia coli O26:H11 str. 11368
Sequence Strain (Species/Organism) Escherichia coli O26:H11 str. 11368
NCBI Gene ID 8473053
NCBI Protein GI 260763803
Locus Tag ECO26_p1-01
Protein Accession YP_003237842.1
Other Database IDs UniProtKB-ID: C8TW27_ECO26
UniRef100: UniRef100_Q5K5Z5
UniRef90: UniRef90_Q5K5Z5
UniRef50: UniRef50_P09985
UniParc: UPI00000B3039
EMBL: AP010954
EMBL-CDS: BAI28729.1
RefSeq_NT: NC_013369.1
EnsemblGenome: EBESCG00000195348.
EnsemblGenome_TRS: EBESCT00000196219
EnsemblGenome_PRO: EBESCP00000183530
GenomeReviews: AP010954_GR
KEGG: eoj:ECO26_p1-01
ProtClustDB: CLSK862057
Taxonomy ID 573235
Plasmid No pO26_1
Gene Starting Position 0
Gene Ending Position 515
Gene Strand (Orientation) +
Protein Name hemolysin C
DNA Sequence 
>gi|260763802:1-515 Escherichia coli O26:H11 str. 11368 plasmid pO26_1, complete sequence
ATGAAATCTAATGCTTTTGACGTCATGGGGAAGGTTGCATGGCTATGGGCCTGTTCTCCTCTGCATAAAA
AATGGCCATTATCTGTTTTTGCTATTAATGTCATACCTGCTATTCAGACAAATCAATTTGCTCTCTTAAT
AAAGGATGAGCTTCCTGTAGCTTTTTGTAGCTGGGCCAGTTTAGATCTGGAATGTGAGGTAAAATATATA
AATGATGTAACATCTTTGTATGCAAAAGACTGGATGTCGGGAGAAAGAAAGTGGTTTATTGACTGGATAG
CTCCATTTGGACACAACATGGAGTTATATAAATACATGAGGAAAAAGTATCCTTATGAGTTATTCAGAGC
AATAAGGTTAGATGAGAGCAGTAAAACAGGAAAAATAGCTGAATTTCATGGAGGGGGGATAGATAAAAAA
CTGGCATCAAAAATATTCAGGCAATACCATCATGAACTTATGTCTGAAGTAAAAAACAGACAAGATTTTA
ATTTTAATATTGAGAAAGAAAACTA
Protein Sequence 
>gi|260763803|ref|YP_003237842.1| hemolysin C [Escherichia coli O26:H11 str. 11368] MKSNAFDVMGKVAWLWACSPLHKKWPLSVFAINVIPAIQTNQFALLIKDELPVAFCSWASLDLECEVKYINDVTSLYAKDWMSGERKWFIDWIAPFGHNMELYKYMRKKYPYELFRAIRLDESSKTGKIAEFHGGGIDKKLASKIFRQYHHELMSEVKNRQDFNFNIEKEN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: hlyC is required for the acylation and therefore activation of the toxin hemolysin which has the ability to lyse several different types of cells (Stanley et al., 1996).
COG COG2994O, under O: Posttranslational modification, protein turnover, chaperones
References
Stanley et al., 1996: Stanley P, Koronakis V, Hardie K, Hughes C. Independent interaction of the acyltransferase HlyC with two maturation domains of the Escherichia coli toxin HlyA. Molecular microbiology. 1996; 20(4); 813-822. [PubMed: 8793877].