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ompA from Escherichia coli O103:H2 str. 12009

Victor ID 3781
Gene Name ompA from Escherichia coli O103:H2 str. 12009
Sequence Strain (Species/Organism) Escherichia coli O103:H2 str. 12009
NCBI Gene ID 8477375
NCBI Protein GI 260843206
Locus Tag ECO103_1003
Protein Accession YP_003220984.1
Other Database IDs UniProtKB-ID: C8U5C1_ECO10
UniRef100: UniRef100_P0A911
UniRef90: UniRef90_B7LNW7
UniRef50: UniRef50_B7LNW7
UniParc: UPI0000130CF0
EMBL: AP010958
EMBL-CDS: BAI29850.1
RefSeq_NT: NC_013353.1
EnsemblGenome: EBESCG00000176465.
EnsemblGenome_TRS: EBESCT00000177817
EnsemblGenome_PRO: EBESCP00000167492
GenomeReviews: AP010958_GR
KEGG: eoh:ECO103_1003
ProtClustDB: PRK10808
Taxonomy ID 585395
Gene Starting Position 1105123
Gene Ending Position 1106163
Gene Strand (Orientation) -
Protein Name outer membrane protein A
DNA Sequence 
>gi|260842239:1105123-1106163 Escherichia coli O103:H2 str. 12009, complete genome
CTTAAGCTTGCGGCTGAGTTACAACGTCTTTGATACCTTTAACTTCGATCTCTACGCGACGATCCGGAGC
CAGGCAGTCGATCAGTGCAGCACGCTGTTTCACGTTGTCACAGGTGTTGCCAGTAACCGGGTTGGATTCG
CCCATACCACGTGCGGAGATCTTGTCTGCCGGGATACCTTTGGAGATCAGGTAATCAACAACAGACTGAG
CACGGCGCTCGGACAGACCCTGGTTGTAAGCGTCAGAACCGATGCGGTCGGTGTAACCCAGAACAACTAC
GGAACCGTCTTTCGGATCCAGGTTGCTCAGCTGGCTGTACAGCTGATCCAGAGCAGCCTGACCTTCCGGT
TTCAGGGTTGCTTTGTTGAAGTTGAACAGAACGTCAGACTTCAGAGTGAAGTGCTTGGTCTGTACTTCCG
GTGCCGGAGCTGGAGCCGGAGCAACTACTGGAGCTGCTTCGCCCTGACCGAAACGGTAGGAAACACCCAG
GCTCAGCATGCCGTTGTCCGGACGAGTGCCGATGGTGTGTGCGTCACCGATGTTGTTGGTCCACTGGTAT
TCCAGACGGGTAGCGATTTCAGGAGTGATCGCGTACTCAACACCGCCAGCGAAGACCGGAGAAACGCCGG
TGTCGTGGTTTTTACCATAAACGTTGGATTTAGTGTCTGCACGCCATACCATACCACCCAGACGAGTGTA
GATGTCCAGGTCGTCAGTGATTGGGTAACCCAGTTTAGCGGTCAGTTGAACGCCCTGAGCTTTGTATGCA
CCGTTTTCAACGCTGCCTTTGTACGGCATACGACCTAACCAGTCGTAACCCATTTCAAAGCCAACATACG
GGTTAACCTGGTAACCACCAAAAGCACCAGCGCCCAGTTGGTTTTCATGGGTCGGGCCATTGTTGTTGAT
GAAACCAGTGTCATGGTACTGGGACCAGCCCAGTTTAGCACCAGTGTACCAGGTGTTATCTTTCGGAGCG
GCCTGCGCTACGGTAGCGAAACCAGCCAGTGCCACTGCAATCGCGATAGCTGTCTTTTTCA
Protein Sequence 
>gi|260843206|ref|YP_003220984.1| outer membrane protein A [Escherichia coli O103:H2 str. 12009] MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIKDVVTQPQA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: OmpA− strains are unable to cause actin condensation needed for invasion of brain epithelial cells (Prasadarao et al., 1999).
COG COG2885M, under M: Cell wall/membrane/envelope biogenesis
References
Prasadarao et al., 1999: Prasadarao NV, Wass CA, Stins MF, Shimada H, Kim KS. Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infection and immunity. 1999; 67(11); 5775-5783. [PubMed: 10531228].