Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

espA from Escherichia coli O103:H2 str. 12009

Victor ID 3775
Gene Name espA from Escherichia coli O103:H2 str. 12009
Sequence Strain (Species/Organism) Escherichia coli O103:H2 str. 12009
NCBI Gene ID 8475189
NCBI Protein GI 260845685
Locus Tag ECO103_3606
Protein Accession YP_003223463.1
Other Database IDs UniProtKB-ID: C8TWL7_ECO10
UniRef100: UniRef100_Q5K5Q4
UniRef90: UniRef90_O33976
UniRef50: UniRef50_O87743
UniParc: UPI00004B4E31
EMBL: AP010958
EMBL-CDS: BAI32329.1
RefSeq_NT: NC_013353.1
EnsemblGenome: EBESCG00000176410.
EnsemblGenome_TRS: EBESCT00000178301
EnsemblGenome_PRO: EBESCP00000167081
GenomeReviews: AP010958_GR
KEGG: eoh:ECO103_3606
ProtClustDB: CLSK701598
Taxonomy ID 585395
Gene Starting Position 3683046
Gene Ending Position 3683624
Gene Strand (Orientation) -
Protein Name translocon EspA
DNA Sequence 
>gi|260842239:3683046-3683624 Escherichia coli O103:H2 str. 12009, complete genome
GTTATTTACCAAGGGATATTGCTGAAATAGTTCTGTATTGCAGTGACTGAATATCAGCACGTGCACTCGT
TAATAAGTTTAACGTATTTGACATTTGCTGTATTTCAAGCTGGCTATTATTCACTACCGTGGTCAAGTTA
TTCGATTTGGCCGAAATAGCTGCCTTCACCGTTTGCAAATCACCAGCGCCTAATTCAACAGTAATGTCTT
TTACATCACTGACCGTAATGCCATTACGAGGATCTTTTATATAGTCGATCACTTCTTGAGGAAGTTTGGC
TTTCGCATCCTTGTTAGAACTGCTCTGAACCTCAGCAATTTTAGCATCCACAAGATTAGCCATTTTTTGG
GCAGTGGTTGACTCCTTAGATGCCTCATTCATATCAGCAAACTTTGCAATCGACAGATCGCTTTGTGCCT
GATACATATAGGCAAACATGAGAAGCGCAGCCTGAAAAACACCGACTTCATTAAATAGCTGAACTACTTC
GTCTTTCGACATGCTGCCTAAGTCATAGACTGTCGATGTCGAAGTACTCGCGTTCGCACTGGCAACTGAT
GTTGCAGTTGATGTATCCA
Protein Sequence 
>gi|260845685|ref|YP_003223463.1| translocon EspA [Escherichia coli O103:H2 str. 12009] MDTSTATSVASANASTSTSTVYDLGSMSKDEVVQLFNEVGVFQAALLMFAYMYQAQSDLSIAKFADMNEASKESTTAQKMANLVDAKIAEVQSSSNKDAKAKLPQEVIDYIKDPRNGITVSDVKDITVELGAGDLQTVKAAISAKSNNLTTVVNNSQLEIQQMSNTLNLLTSARADIQSLQYRTISAISLGK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion of espA in STEC abolished ability to attach to HeLa cells and induce actin rearrangements (Ebel et al., 1998).
References
Ebel et al., 1998: Ebel F, Podzadel T, Rohde M, Kresse AU, Krämer S, Deibel C, Guzmán CA, Chakraborty T. Initial binding of Shiga toxin-producing Escherichia coli to host cells and subsequent induction of actin rearrangements depend on filamentous EspA-containing surface appendages. Molecular microbiology. 1998; 30(1); 147-161. [PubMed: 9786192].