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espD from Escherichia coli O103:H2 str. 12009

Victor ID 3774
Gene Name espD from Escherichia coli O103:H2 str. 12009
Sequence Strain (Species/Organism) Escherichia coli O103:H2 str. 12009
NCBI Gene ID 8475188
NCBI Protein GI 260845684
Locus Tag ECO103_3605
Protein Accession YP_003223462.1
Other Database IDs UniProtKB-ID: C8TWL6_ECO10
UniRef100: UniRef100_C8TWL6
UniRef90: UniRef90_O88127
UniRef50: UniRef50_P71215
UniParc: UPI0001B5B2BB
EMBL: AP010958
EMBL-CDS: BAI32328.1
RefSeq_NT: NC_013353.1
EnsemblGenome: EBESCG00000176453.
EnsemblGenome_TRS: EBESCT00000177687
EnsemblGenome_PRO: EBESCP00000165513
GenomeReviews: AP010958_GR
KEGG: eoh:ECO103_3605
ProtClustDB: CLSK334861
Taxonomy ID 585395
Gene Starting Position 3681891
Gene Ending Position 3683033
Gene Strand (Orientation) -
Protein Name translocon EspD
DNA Sequence 
>gi|260842239:3681891-3683033 Escherichia coli O103:H2 str. 12009, complete genome
ATTAAACTCGACCACTAACAATACGGCTATTTACTCGTGCTGAGTCGGATATTAACTGAGAAGCATTTTG
TAAATAGCTTGCCTGGTTTCGCAACTCGGCTGCAGCTTTATCCAGCTCAACCTTCGCACTCTCACCCAGG
TTTTCACTCTGTCGAGTTAAGTTTTGCACCGCGTAAGCAGATAACTGAGCCAATATGCTGTATTGCGCAG
AATCATTATTCAGCACAGTTGTCCCAATAGAACGTGCAGAGGTCGTAAATCCATTTGCCGTTGCCGCAAC
TTTTGAAACAACGTTCTCAACAAATACATCGGCCAGTTTAGTAACTGTTTTCACGATGTTTGAACCAACT
TTGTTAGCGACATCGCCAACTTTAGACATAAGTGAAGACACCCCGCCAATGCCGGCTGTCAGAATACTTG
CAGCAATAGATACTCCGCCAAAGACTTGCGCTGCTGTCTTTAACGCCTGCGGGGCCTTATCGCCCATTAC
ATCAACTGCAGTTTGCAGTGCCATTGCTGTTGCGCTAACGGCAACAACAGCCCAGAGTGCCGGGTTAAAA
AAAGCTGCAATAGCAGTTACCGCGACGCCCAACCAACCAAAGACCTGACCAACAATTTTACTTTTTTGTG
CTTTCTCTTCGGCTTTCTGTTGTTCTTCGAGCTGCTTTTTAAACTCCAGCGTTTTATTATCCAGCGCCTT
ATTTTGCCCATCCGTGTAGATCTCGTTGGAGTTTTTCATACTCGCAACTTTCTGCGCTGAAGCATCCAGG
GATAACAGGGTGACCATCATCATCATGGCCTGAGGGTCAACGTTATTCACCTGAGAAAGATAAGGATAGC
CAGAGCTTGCATTCTGAGTGCTGCGCTGTGGTTCGGTTCCCTCTGTTCGACTCCTAACTTCACCACTAAT
ACCACCAAACAGTTTACTCAGGACATCCTCAGCAGCAGAGGGCGTCACTAATGAGTGGCCTGCCGGTGGC
GTTGGTAAAGCGGTACTTTCTGTCCAACTTGCTGATGGGGCCGTGGATTTAACCAGTTGTAAATCCAGCG
CGGAAGTCACTTCAGGCTGATTAATACCTGAAGTAGCCGTAGCAGCGCTGGCCCCAGACCTCATCGACTG
GATATCGCTATTTACATTGAGCA
Protein Sequence 
>gi|260845684|ref|YP_003223462.1| translocon EspD [Escherichia coli O103:H2 str. 12009] MLNVNSDIQSMRSGASAATATSGINQPEVTSALDLQLVKSTAPSASWTESTALPTPPAGHSLVTPSAAEDVLSKLFGGISGEVRSRTEGTEPQRSTQNASSGYPYLSQVNNVDPQAMMMMVTLLSLDASAQKVASMKNSNEIYTDGQNKALDNKTLEFKKQLEEQQKAEEKAQKSKIVGQVFGWLGVAVTAIAAFFNPALWAVVAVSATAMALQTAVDVMGDKAPQALKTAAQVFGGVSIAASILTAGIGGVSSLMSKVGDVANKVGSNIVKTVTKLADVFVENVVSKVAATANGFTTSARSIGTTVLNNDSAQYSILAQLSAYAVQNLTRQSENLGESAKVELDKAAAELRNQASYLQNASQLISDSARVNSRIVSGRV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: espD deletion mutant of the enterohemorrhagic E. coli (EHEC) strain EDL933 had impaired attachment to HeLa cells (Kresse et al., 1999).
COG COG5613S, under S: Function unknown
References
Kresse et al., 1999: Kresse AU, Rohde M, Guzmán CA. The EspD protein of enterohemorrhagic Escherichia coli is required for the formation of bacterial surface appendages and is incorporated in the cytoplasmic membranes of target cells. Infection and immunity. 1999; 67(9); 4834-4842. [PubMed: 10456938].