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ler from Escherichia coli O103:H2 str. 12009

Victor ID 3767
Gene Name ler from Escherichia coli O103:H2 str. 12009
Sequence Strain (Species/Organism) Escherichia coli O103:H2 str. 12009
NCBI Gene ID 8474199
NCBI Protein GI 260845717
Locus Tag ECO103_3638
Protein Accession YP_003223495.1
Other Database IDs UniProtKB-ID: C8TWP9_ECO10
UniRef100: UniRef100_Q9AJ33
UniRef90: UniRef90_C7BUR5
UniRef50: UniRef50_Q8VTF2
UniParc: UPI000005D12E
EMBL: AP010958
EMBL-CDS: BAI32361.1
RefSeq_NT: NC_013353.1
EnsemblGenome: EBESCG00000175802.
EnsemblGenome_TRS: EBESCT00000177783
EnsemblGenome_PRO: EBESCP00000167555
GenomeReviews: AP010958_GR
KEGG: eoh:ECO103_3638
ProtClustDB: CLSK334877
Taxonomy ID 585395
Gene Starting Position 3709698
Gene Ending Position 3710087
Gene Strand (Orientation) -
Protein Name transcription regulator Ler
DNA Sequence 
>gi|260842239:3709698-3710087 Escherichia coli O103:H2 str. 12009, complete genome
GTTAAATATTTTTCAGCGGTATTATTTCGTCTTCGGTGTCCTTCACAAGAAAATCTTCTTTCTTCATTCC
ATTCAACAGTGCTTCTTTAAGCCAGCGTGGCTGTCGGCCAACTCCCGACCAGGTCTGCCCTTCTTCATTG
CGATAATAAACTCCTTTCGATGAGTTCCGGCGAGCAAGGCCATCATCAGGCACATTAGTATATCCCAGCT
CTTGTAGGGTTATATTGTAATAAGTAATCTGCTTTTGAATCGACTCAATTACACTTTGAATTTCCTGCTC
TCGCAGTCGCTTTGCTTCCTGTTGTAACACTTCAATTTGCTCAATAAGCTGAATGTATGGGCTTGTTGTG
TGCGAATTAGTTTCCATATTCATAATAAATAATCTCCGCA
Protein Sequence 
>gi|260845717|ref|YP_003223495.1| transcription regulator Ler [Escherichia coli O103:H2 str. 12009] MRRLFIMNMETNSHTTSPYIQLIEQIEVLQQEAKRLREQEIQSVIESIQKQITYYNITLQELGYTNVPDDGLARRNSSKGVYYRNEEGQTWSGVGRQPRWLKEALLNGMKKEDFLVKDTEDEIIPLKNI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ler mutants had less adhesion to HeLa cells, ler is a regulator of many virulence genes in the LEE PAI which are needed for adherence (Torres et al., 2008).
COG COG2916R, under R: General function prediction only
References
Torres et al., 2008: Torres AG, Slater TM, Patel SD, Popov VL, Arenas-Hernández MM. Contribution of the Ler- and H-NS-regulated long polar fimbriae of Escherichia coli O157:H7 during binding to tissue-cultured cells. Infection and immunity. 2008; 76(11); 5062-5071. [PubMed: 18794291].