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escN from Escherichia coli O103:H2 str. 12009

Victor ID 3766
Gene Name escN from Escherichia coli O103:H2 str. 12009
Sequence Strain (Species/Organism) Escherichia coli O103:H2 str. 12009
NCBI Gene ID 8474193
NCBI Protein GI 260845697
Locus Tag ECO103_3618
Protein Accession YP_003223475.1
Other Database IDs UniProtKB-ID: C8TWM9_ECO10
UniRef100: UniRef100_Q5K5P2
UniRef90: UniRef90_O85632
UniRef50: UniRef50_O85632
UniParc: UPI00004B4E38
EMBL: AP010958
EMBL-CDS: BAI32341.1
RefSeq_NT: NC_013353.1
EnsemblGenome: EBESCG00000178823.
EnsemblGenome_TRS: EBESCT00000180362
EnsemblGenome_PRO: EBESCP00000169375
GenomeReviews: AP010958_GR
KEGG: eoh:ECO103_3618
ProtClustDB: CLSK334788
Taxonomy ID 585395
Gene Starting Position 3695602
Gene Ending Position 3696942
Gene Strand (Orientation) -
Protein Name translocator EscN
DNA Sequence 
>gi|260842239:3695602-3696942 Escherichia coli O103:H2 str. 12009, complete genome
TTCAGGCAACCACTTTGAATAGGCTTTCAATCGTTTTTTCGTAACTACTGATATCTTTGGTGCTTTGTTG
TATAAAGCTCTGAATTGCTTTCCTGTTTTTTATTGCCTTATCCGCTTCAGGATCTTGCCCCATCGTGTAC
TCACCAATACGAATAAGCAGCTCAATATTTTTATAGGTTGCGATAAGCTTTTTGCATTCTGCCGCCGCAC
GCAAATGCTCCGATGTAACAACATTATGCATAACACGACTGGCGCTTAAACCAATATCAATTGCAGGAAA
ATGATTTTCCTCTGCAAGTTCTCGGGTAAGCACAATGTGCCCATCAAGAATAGAGCGGACTTCATCACCA
ATGGGATCATTAACATTATCGCTTTCTAACAACACCGTATAAATCGCGGTTATTGAGCCTTTTGGCGCAG
GCCCCGCACGCTCTAATAATTTGGGTAACGAGGAAAAAACACTCGGAGGGAATCCCCCCCTTACATCAGG
CTCTCCCGATGCAAGCCCAACATCACGCGCGGCTCGGGCATAACGAGTTACGGAATCCATCATTAATAAT
ACATTTTTGCCCTGATCCCGGAAGAACTCTGCAATGGTTGTCGCCGTAAATGCGGCCTTCATTCTTTCCA
GCGCGGGACGGTCTGACGTTGTGACGACCAGTACACATTTAGAAAGCGTGGATTGAGGTAAAAGCGCGAG
GAATTCATTTACTTCGCGACCACGCTCGCCGATAAGGGCAAGGACAATAATATCCGCGGATGCGCCATTA
CAAATCATTCCCAAAAGCGTACTTTTACCAACGCCGGACCCCGCGAAAATACCGATACGTTGCCCAATAC
CGCAAGTAAGTAAACCATCTATTGCCCTGACGCCAAGCGTAAATGGCTGATCAATAACCTGCCTTAATAA
AGGATCGGGGGGTTCAGCATACAAACTGCGTTCAAACGGAAGATAAGGTGCAGTAATATTGCTCCCCATT
GGTCTGCCTATACCATCAACCAGTCGCCCAAGGAGTTCGTCCCCAACACGAATCTTGAACTCATCCCCCT
GATAACTTAGCCACTGGCCACAATACATGCCGGAAATATGCTCAAAAGGCAGCAGGAAAACCTCATCTTC
ATCAATAGCGATCACCTCAGCTAAACGTTGACTGGGTTCTATCCTGTAAAAGGCGCCAATACGCGCTTTT
GGTAAACGCGCCTTGATAATCGTCCCGCCGATATTGGTAATCTTGCCTTCATATCTGGTAGACGAATTTA
ATGATAATGTCGGCACAGTGCTATTGAGCACTCTCTGGATACGTGGGTATCTTTCCAATACAAAATCATG
CTCTGAAATCA
Protein Sequence 
>gi|260845697|ref|YP_003223475.1| translocator EscN [Escherichia coli O103:H2 str. 12009] MISEHDFVLERYPRIQRVLNSTVPTLSLNSSTRYEGKITNIGGTIIKARLPKARIGAFYRIEPSQRLAEVIAIDEDEVFLLPFEHISGMYCGQWLSYQGDEFKIRVGDELLGRLVDGIGRPMGSNITAPYLPFERSLYAEPPDPLLRQVIDQPFTLGVRAIDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGASADIIVLALIGERGREVNEFLALLPQSTLSKCVLVVTTSDRPALERMKAAFTATTIAEFFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFSSLPKLLERAGPAPKGSITAIYTVLLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLRAAAECKKLIATYKNIELLIRIGEYTMGQDPEADKAIKNRKAIQSFIQQSTKDISSYEKTIESLFKVVA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: deletion of escN abolished pathogenicity in infant rabbits compared to wild-type EHEC (Ritchie and Waldor, 2005).
COG COG1157NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Ritchie and Waldor, 2005: Ritchie JM, Waldor MK. The locus of enterocyte effacement-encoded effector proteins all promote enterohemorrhagic Escherichia coli pathogenicity in infant rabbits. Infection and immunity. 2005; 73(3); 1466-1474. [PubMed: 15731044].